血管性痴呆中医证候与神经心理学指标相关性分析

发布时间：2018-08-07 19:46

【摘要】：目的:探讨血管性痴呆(VD)中医证候特点及与神经心理学指标相关性。方法:采集VD患者95例,依据中医辨证量表(SDSVD)进行中医辨证分型,统计各证候出现率,对证候积分与MMSE和ADL-R评分、与定向力、记忆力、计算力、回忆能力、语言能力评分进行相关分析。结果:VD患者证候出现率从大到小依次为:肾精亏虚证痰浊阻窍证瘀血阻络证腑滞浊留证气血亏虚证火热内盛证肝阳上亢证。VD患者的各证候积分与MMSE和ADL-R评分均未见显著相关性(R0.3,P0.05),肾精亏虚、气血亏虚证与记忆力呈显著负相关(P0.01,P0.05)。结论:VD的证候主要以肾精亏虚证、痰浊阻窍证、瘀血阻络证最为常见,并且肾精亏虚越重,记忆力就越差,提示在临床中应重视补肾、活血、化痰治法的运用,尤其补肾填精对改善记忆力尤为重要。
[Abstract]:Objective: to investigate the characteristics of TCM syndromes of vascular dementia (VD) and its correlation with neuropsychological indexes. Methods: 95 VD patients were collected and classified according to TCM syndrome differentiation scale (SDSVD). The occurrence rate of each syndrome was counted. The scores of syndromes, MMSE and ADL-R, and orientation, memory, calculation and recall ability were analyzed. Language ability score was analyzed. Results the occurrence rate of the syndrome in the patients with VW VD was as follows: the syndrome of deficiency of kidney essence, phlegm, turbidity, obstruction of resuscitation, blood stasis, stagnation of collaterals, retention of qi and blood deficiency, fire and heat, hyperactivity of liver-yang, and the scores of MMSE and ADL-R of the patients with hyperactivity of liver-yang. Significant correlation was found (P 0.05), deficiency of kidney essence, Deficiency of qi and blood was negatively correlated with memory (P 0.01 P 0.05). Conclusion the main syndromes of VW VD are deficiency of kidney essence, stagnation of phlegm and orifices, stagnation of collaterals by blood stasis, and the more serious deficiency of kidney essence, the worse memory. It is suggested that the application of the methods of tonifying the kidney, activating blood circulation and resolving phlegm should be paid more attention to in clinical practice. Especially tonifying kidney and filling essence is very important to improve memory.
【作者单位】：河北中医学院;河北省心脑血管病中医药防治重点实验室;河北医科大学;北京市海淀区北太平庄社区卫生服务中心;
【基金】：河北省自然科学基金项目(No.H2015423057) 河北省教育厅高等学校科学技术研究项目(No.Z2014061) 河北省中医药管理局资助课题(No.2013001)~~
【分类号】：R277.7

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