蒙药十三味红花密诀丸治疗过敏性鼻炎的临床疗效观察

发布时间：2018-08-16 19:17

【摘要】：目的根据治疗前后鼻炎患者症状评分以及血液中IgE数值的变化程度,观察蒙药十三味红花密诀丸治疗过敏性鼻炎的临床疗效。方法将62例患者病程1年以上过敏性鼻炎患者,按入组时间先后顺序,随机分为蒙药组(治疗组)与中药组(对照组),蒙药组32例,中药组30例。蒙药组患者口服十三味红花密诀丸,每日2次,一次10粒,中药组患者口服千柏鼻炎片,每日3次,一次4片,蒙药组与中药组均服药4周。建立患者资料调查表与症状积分表,记录患者治疗前与服药满一周后的症状积分,记录患者治疗前后血液中IgE数值。将原始数据录入Excel,对所有数据进行整理。用SPSS13.0统计软件对数据进行处理分析,评价疗效。结果在症状评分方面,两组患者治疗后症状评分较治疗前症状评分,有明显下降,有极为显著差异(P0.01),说明两种药物均能够有效改善过敏性鼻炎患者的临床症状;组间对比,蒙药组患者在第1周服药后,与服药前的症状积分差值明显大于中药组,统计学有极显著差异(P0.01),第2周与第3周两组患者症状积分差值没有统计学差异(P0.05),第4周蒙药组患者症状积分差值较中药组患者有显著差异(P0.05);在血液IgE方面,两组患者治疗后IgE数值与治疗前相比,有一定程度下降,有极为显著差异(P0.01),说明两种药物均能有效降低血液中IgE数值;蒙药组治疗前后血液IgE差值与中药组IgE差值进行比较,无差异(P0.05),说明两种药物在降低血液IgE数值方面无差异。结论两种药物均能够有效降低过敏性鼻炎患者的临床症状,但十三味红花密诀丸能够更好的改善过敏性鼻炎患者的典型症状;在影响过敏性鼻炎患者体内血液IgE数值方面,两种药物均有疗效,无明显差异(P0.05)。蒙药十三味红花密诀丸不但能改善过敏性鼻炎的典型症状,也能降低患者血清总IgE水平,从而达到治疗过敏性鼻炎,可以在临床上推广使用。
[Abstract]:Objective to observe the clinical effect of 13 kinds of Mongolian medicine on allergic rhinitis according to the change of symptom score and IgE value of rhinitis patients before and after treatment. Methods 62 patients with allergic rhinitis were randomly divided into Mongolian medicine group (treatment group) and Chinese medicine group (control group), Mongolian medicine group (32 cases) and Chinese medicine group (30 cases). The patients in the Mongolian medicine group were given 13 kinds of safflower secret pills twice a day, 10 tablets once a day, and the patients in the traditional Chinese medicine group took Qianbai rhinitis tablets 3 times a day, 4 tablets once a day, and both the Mongolian medicine group and the Chinese medicine group took medicine for 4 weeks. The symptom scores before and after treatment were recorded and the IgE values of blood were recorded before and after treatment. Input raw data into Excel and organize all data. SPSS13.0 statistical software was used to analyze the data and evaluate the curative effect. Results in the aspect of symptom score, the symptom score of the two groups after treatment was significantly lower than that before treatment (P0.01), indicating that the two drugs can effectively improve the clinical symptoms of patients with allergic rhinitis. The difference of symptom score between the Mongolian medicine group and the pre-medication group was significantly higher than that in the traditional Chinese medicine group after the first week of medication. There was very significant difference in statistics (P0.01). There was no significant difference between the two groups in symptom score difference between the second week and the third week (P0.05). At the 4th week, there was significant difference between the Mongolian medicine group and the traditional Chinese medicine group (P0.05); in blood IgE, there was no significant difference between the two groups (P0.05). Compared with before and after treatment, the IgE value of the two groups decreased to a certain extent, and there was a significant difference (P0.01), indicating that the two drugs can effectively reduce the value of IgE in the blood, and the difference of blood IgE between the Mongolian medicine group and the traditional Chinese medicine group before and after treatment was compared with that of the traditional Chinese medicine group. There was no difference (P0.05), indicating that there was no difference between the two drugs in reducing blood IgE values. Conclusion both drugs can effectively reduce the clinical symptoms of patients with allergic rhinitis, but Shiwei Honghua Mi Pill can improve the typical symptoms of allergic rhinitis patients, and affect the IgE value of blood in allergic rhinitis patients. There was no significant difference between the two drugs (P0.05). The Mongolian medicine Thirteen Red Flower Milk Pill can not only improve the typical symptoms of allergic rhinitis, but also reduce the serum total IgE level of the patients, so as to achieve the treatment of allergic rhinitis, and can be popularized in clinical use.
【学位授予单位】：内蒙古医科大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R29

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