益坤饮配合心理干预及八段锦功法改善围绝经期患者抑郁症状的临床疗效观察

发布时间：2018-08-21 07:32

【摘要】：目的：通过观察益坤饮配合心理干预及八段锦功法锻炼改善围绝经期患者抑郁症状的临床疗效,为今后从多途径入手,改善围绝经期患者抑郁症状提供理论指导。方法：采用益坤饮联合心理干预及八段锦运动功法治疗肾虚肝郁型围绝经期抑郁症状患者20例,对照组也选取20例,对照组仅予口服益坤饮。观察两组患者治疗前、治疗后的汉密尔顿抑郁量表(HAMD)评分、中医证候半定量积分、改良Kupperman评分情况。结果：两组患者改良Kupperman评分、中医症状积分、HAMD量表评分,三者在治疗前没有统计学差异。治疗后三项积分均较治疗前明显下降(P0.05),组内与组间比较均具有统计学差异。在临床疗效上治疗组比对照组高,但没有统计学差异。经治疗后,两组患者的激素水平均较治疗前有所改善,但组间比较没有统计学差异。相关性分析：患者经历负性生活事件、对围绝经期相关知识匮乏、平素缺乏运动、无家人的陪伴均为围绝经期抑郁症状产生的高危因素。治疗过程中无不良反应。结论：患者经历负性生活事件、对围绝经期相关知识匮乏、平素缺乏运动、无家人的陪伴均为围绝经期抑郁症状产生的高危因素。益坤饮改善肾虚肝郁型围绝经期抑郁症状临床疗效显著,应用中药的基础上配合心理干预和八段锦功法锻炼效果更佳。
[Abstract]:Objective: to observe the clinical effect of Yikun Yin in combination with psychological intervention and Baduanjin exercises to improve the depressive symptoms of peri-menopausal patients, and to provide theoretical guidance for improving the depressive symptoms of peri-menopausal patients in the future. Methods: 20 patients with peri-menopausal depression of kidney deficiency and liver-depression type were treated with Yikun Yin combined with psychological intervention and Baduanjin exercise skill method. 20 patients in the control group were also selected and the control group was only given Yikun Yin orally. The (HAMD) score of Hamilton Depression scale, the semi quantitative score of TCM syndrome and the improved Kupperman score were observed before and after treatment. Results: there was no statistical difference between the two groups before treatment with modified Kupperman score, TCM symptom score and Hamd scale. After treatment, the three scores were significantly lower than those before treatment (P0.05), there were statistical differences between the group and the group. The clinical effect of the treatment group was higher than that of the control group, but there was no statistical difference. After treatment, the hormone levels of the two groups were improved compared with those before treatment, but there was no statistical difference between the two groups. Correlation analysis: patients experienced negative life events, lack of knowledge about perimenopausal period, lack of exercise, lack of family members were the high risk factors of depression symptoms in perimenopausal period. There were no adverse reactions during the treatment. Conclusion: the negative life events lack of knowledge about perimenopausal period lack of exercise and absence of family members are the high risk factors of depression in perimenopausal period. Yikun Yin improved the symptoms of depression in perimenopausal period of kidney deficiency and liver-depression type, and the effect of Chinese medicine combined with psychological intervention and Baduanjin method was better than that of traditional Chinese medicine.
【学位授予单位】：南京中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R277.7

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