糖尿病足中医辨证分型与病程、糖化血红蛋白、踝肱指数等的相关性分析

发布时间：2018-08-28 06:16

【摘要】：目的：对糖尿病足中医辨证分型与糖尿病病程、糖化血红蛋白(HbAlc)、踝肱比值(ABI)的相关性进行分析,为糖尿病足中医辨证分型提供部分客观依据。方法：采用回顾性住院病历资料调查统计方法,共收集2012年-2015年浏阳市中医医院(湖南中医药大学附属第二中西医结合医院)内分泌糖尿病科糖尿病足病例82例,采集一般资料(性别、年龄、糖尿病病程、糖尿病足病程、Wagner分级等)、中医症候以及实验室检查资料(空腹血糖(FPG)、HbAlc、ABI等),最后运用SPSS17.0统计软件对数据进行统计分析。结果：1.82例糖尿病足中,男性55例,女性27例,平均年龄(60.7±11.6)岁,82.4%的患者年龄50岁,平均糖尿病病程(10.0±6.3)年,77.5%的患者糖尿病病程在5年以上,88.5%的患者HbAlc6.5%。2.寒湿阻络证的糖化血红蛋白水平高于其他各证型,差异有统计学意义(P0.05)。3.热毒伤阴证的FPG水平明显高于其他各证型,差异有统计学意义(P0.05)。4.气血两虚证ABI指数较低,与其余各组比较差异具有统计学意义(P0.05)。5.糖尿病足病程中湿热毒盛型病程最短,与各证型间比较,差异具有统计学意义(p0.01)。结论：1.糖尿病足中医不同证型与糖化血红蛋白、空腹血糖、病程、踝肱指数有一定的相关性。2.较高水平的糖化血红蛋白和空腹血糖可分别作为糖尿病足寒湿阻络证和热毒伤阴证辨证的临床参考指标。3.较低水平的ABI指数可作为气血两虚型的临床客观指标。4.在糖尿病足早期以湿热毒盛证为主,随着糖尿病足时间延长,证型以寒湿阻络、气血两虚、血脉瘀阻为主。
[Abstract]:Objective: to analyze the correlation between TCM syndrome differentiation of diabetic foot and the course of diabetes and (ABI) of glycosylated hemoglobin (HbAlc), ankle-brachial ratio in order to provide some objective basis for TCM syndrome differentiation of diabetic foot. Methods: a total of 82 cases of diabetic foot with endocrine diabetes mellitus were collected from 2012 to 2015 in Liuyang traditional Chinese Medicine Hospital (the second affiliated Hospital of Integrated traditional Chinese and Western Medicine, Hunan University of traditional Chinese Medicine). General data (sex, age, course of diabetes, disease course of diabetic foot and Wagner grade), TCM symptoms and laboratory data (fasting blood glucose (FPG), HbAlcABI, etc.) were collected. Finally, the data were statistically analyzed by SPSS17.0 software. Results of the 1.82 diabetic feet, 55 were male and 27 were female. The average age of the patients was (60.7 卤11.6) years old (82.4%), the mean course of diabetes was (10.0 卤6.3) years (77.5%), the course of diabetes was more than 5 years (88.5%). The level of glycosylated hemoglobin in cold dampness blocking collaterals syndrome was higher than other syndrome types, the difference was statistically significant (P0.05). 3. The FPG level of heat toxin injury yin syndrome was significantly higher than other syndrome types, the difference was statistically significant (P0.05). 4. Qi and blood deficiency syndrome ABI index was lower, compared with the other groups, the difference was statistically significant (P0.05). 5. In the course of diabetic foot, the course of damp-heat toxin was the shortest, and the difference was statistically significant (p0.01). Conclusion 1. Different syndrome types of diabetic foot have certain correlation with glycosylated hemoglobin, fasting blood glucose, course of disease, ankle brachial index. The higher level of glycosylated hemoglobin and fasting blood glucose can be used as the clinical reference index of syndrome differentiation of cold dampness and collaterals of diabetic foot and heat toxin injury yin syndrome respectively. The lower level of ABI index can be used as a clinical objective index of qi and blood deficiency. 4. In the early stage of diabetic foot, damp-heat toxin was the main syndrome. With the prolongation of diabetic foot time, the syndrome type was cold dampness blocking collaterals, deficiency of qi and blood, and blood stasis.
【学位授予单位】：湖南中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R259

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