针刺联合中药治疗外伤性视神经萎缩临床研究

发布时间：2018-09-01 13:47

【摘要】：目的:观察针刺联合中药治疗外伤性视神经萎缩的临床疗效方法:采用平行随机对照研究的方法,选择符合纳入标准的外伤性视神经萎缩患者40例(46只眼),随机分为治疗组和对照组,对照组予以甲钴胺口服,治疗组在对照组的基础上予以针刺配合逍遥四物汤口服。各组均以30天为一个疗程进行观察,随访一个月。观察入组时、疗程结束后视力、视野、F-VEP、OCT及评分的改变。结果:观察最终病例数为40人(46只眼),实验组及对照组各20人(23只眼)。(1)两组基线资料比较分析:性别、年龄、眼别、病程、及各项检查与评分之间均无差异(p0.05)。(2)各项主要指标治疗前后两组组内比较:治疗前后治疗组的视力、视野改善(p0.01),对照组无显著差异(p0.05)。治疗后治疗组在头痛、眼痛、失眠减轻(p0.01);对照组头痛、眼痛减轻(p0.05)。治疗后两组P波潜伏期缩短,振幅升高(p0.05)。治疗前后平均RNFL值,治疗组无显著性差异(p0.05),对照组下降(p0.01)。结论:1.针刺联合中药逍遥四物汤口服能够改善外伤性视神经萎缩患者视力、视野,使P波潜伏期缩短、振幅升高,减缓损伤进展速度,并能缓解其头痛、眼痛、失眠症状,改善其气滞血瘀情况,与单纯使用甲钴胺口服相比较,疗效更为理想。2.针刺联合中药逍遥四物汤口服安全性良好。
[Abstract]:Objective: to observe the clinical efficacy of acupuncture combined with traditional Chinese medicine in the treatment of traumatic optic atrophy. Forty patients (46 eyes) with traumatic optic atrophy were randomly divided into treatment group and control group. The control group was given megalomide orally, and the treatment group was treated with acupuncture combined with Xiaoyaowu decoction on the basis of the control group. All groups were observed 30 days as a course of treatment and followed up for one month. Visual acuity, visual field and F-VEP Oct were observed at the end of the course of treatment. Results: there were 40 cases (46 eyes), 20 cases (23 eyes,). (1) in the experimental group and 20 cases in the control group. The baseline data of the two groups were compared and analyzed: sex, age, eye type, course of disease, and so on. There was no difference between the two groups before and after treatment (p0. 05). (2). The visual acuity and visual field were improved before and after treatment (p0. 01), but there was no significant difference in the control group (p0. 05). After treatment, headache, eye pain and insomnia were alleviated in the treatment group (p0.01), and headache and eye pain in the control group (p0.05). After treatment, P wave latency was shortened and amplitude increased in both groups (p0.05). There was no significant difference in average RNFL before and after treatment in the treatment group and the control group (p 0.01). Conclusion 1. Acupuncture combined with Xiaoyao Siwu decoction can improve the visual acuity and visual field of the patients with traumatic optic atrophy, shorten the latency of P wave, increase the amplitude, slow down the progress of injury, and alleviate the symptoms of headache, eye pain and insomnia. The effect of improving qi stagnation and blood stasis was better than that of mecoamin alone. Acupuncture combined with Chinese medicine Xiaoyao Siwu decoction oral safety is good.
【学位授予单位】：云南中医学院
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R276.7

【参考文献】