中药治疗阴道病研究进展
发布时间：2018-09-05 06:10
【摘要】：阴道病又名阴道炎症,是妇科门诊多见和频繁发生的病症,具体指阴道黏膜及黏膜下相关组织的炎症。细菌性阴道病(bacterial vaginosis,BV)和假丝酵母菌性阴道病(candidal vaginitis,CV)是2种常见的阴道疾病,对女性的日常生活和学习造成了极大的影响。目前,对于BV和CV的治疗方法有了一定的改进和提升,从原来的西药或者抗生素治疗变为如今的完全中药方剂及中西药结合方剂治疗,并且在预防BV和CV方面也有了不错的发展。与西药或抗生素相比,中药可辨证论治,疗效稳定且较好、副作用极少,患者易接受。恢复正常的阴道微生物生态环境是治愈阴道病的根本,中药对阴道病的治疗恰好从这个目的出发,但可用于治疗BV和CV的中药材种类繁多且治疗机制复杂,本文通过查阅近年来的权威数据库中中英文文献,对BV和CV的发病机制、用于治疗BV和CV的常见中药以及中药治疗BV和CV的治疗机制进行阐述,以期为反复发作的BV和CV的治疗和新药研发提供新的思路。文章总结了BV的3种发病机制和CV发病机制的5个过程。通过统计,能够治疗BV的主要中药有123种,能够治疗CV的主要中药有133种,能够治疗这两种病的主要中药有84种,且治疗BV和CV的主要药用成分有生物碱、苷类、酚类、挥发油、绿原酸、黄酮类、色素、香豆素等。中药治疗BV和CV的机制:体外抑菌实验、其他抗菌药物渗透率增加、细胞内溶物外漏、机体免疫力提高、中西医结合治疗。文章最后对中药治疗BV和CV过程中存在的问题提出了相应的可行性建议。
[Abstract]:Vaginosis, also known as vaginitis, is a common and frequent disease in gynecological clinic, specifically refers to inflammation of vaginal mucosa and submucous tissue. Bacterial vaginosis (bacterial vaginosis,BV) and Candida vaginalis (candidal vaginitis,CV) are two common vaginal diseases, which have a great impact on women's daily life and study. At present, the treatment methods for BV and CV have been improved and upgraded, from the original western medicine or antibiotic treatment to the complete traditional Chinese medicine prescription and the combination of Chinese and western medicine prescription treatment. And in the prevention of BV and CV has a good development. Compared with western medicine or antibiotics, traditional Chinese medicine can be dialectically treated, with stable and better curative effect, few side effects and easy acceptance by patients. Restoring the normal ecological environment of vaginal microorganism is the fundamental to cure vaginosis. The treatment of vaginosis by traditional Chinese medicine is based on this purpose, but there are many kinds of traditional Chinese medicines used to treat BV and CV and the mechanism of treatment is complicated. In this paper, the pathogenesis of BV and CV, the common Chinese medicine for BV and CV, and the therapeutic mechanism of Chinese medicine for BV and CV are expounded by consulting the English literature in the authoritative database in recent years. In order to provide new ideas for the treatment of recurrent BV and CV and the development of new drugs. In this paper, three kinds of pathogenesis of BV and five processes of pathogenesis of CV were summarized. According to statistics, there are 123 kinds of main Chinese medicines that can treat BV, 133 kinds of main Chinese medicines that can treat CV, 84 kinds of main Chinese medicines that can treat these two diseases, and the main medicinal components of treating BV and CV are alkaloids, glycosides, phenols. Volatile oil, Lv Yuan acid, flavonoids, pigment, coumarin, etc. The mechanism of traditional Chinese medicine in treating BV and CV: in vitro bacteriostatic experiment, other antimicrobial drug permeability increased, intracellular dissolution leakage, body immunity improved, integrated Chinese and western medicine treatment. Finally, some feasible suggestions are put forward for the treatment of BV and CV with traditional Chinese medicine.
【作者单位】： 陕西理工大学陕西省资源生物重点实验室;陕西理工大学生物科学与工程学院;青海大学农林科学院;汉中天然谷生物科技股份有限公司;
【基金】：陕西省科技厅社会发展项目(2014K13-23) 秦巴山区生物资源综合开发协同创新中心项目(QBXT-Z(Y)-15-2) 陕西理工大学研究生创新基金项目(SLGYCX1721)
【分类号】：R271.9
本文编号：2223427
[Abstract]:Vaginosis, also known as vaginitis, is a common and frequent disease in gynecological clinic, specifically refers to inflammation of vaginal mucosa and submucous tissue. Bacterial vaginosis (bacterial vaginosis,BV) and Candida vaginalis (candidal vaginitis,CV) are two common vaginal diseases, which have a great impact on women's daily life and study. At present, the treatment methods for BV and CV have been improved and upgraded, from the original western medicine or antibiotic treatment to the complete traditional Chinese medicine prescription and the combination of Chinese and western medicine prescription treatment. And in the prevention of BV and CV has a good development. Compared with western medicine or antibiotics, traditional Chinese medicine can be dialectically treated, with stable and better curative effect, few side effects and easy acceptance by patients. Restoring the normal ecological environment of vaginal microorganism is the fundamental to cure vaginosis. The treatment of vaginosis by traditional Chinese medicine is based on this purpose, but there are many kinds of traditional Chinese medicines used to treat BV and CV and the mechanism of treatment is complicated. In this paper, the pathogenesis of BV and CV, the common Chinese medicine for BV and CV, and the therapeutic mechanism of Chinese medicine for BV and CV are expounded by consulting the English literature in the authoritative database in recent years. In order to provide new ideas for the treatment of recurrent BV and CV and the development of new drugs. In this paper, three kinds of pathogenesis of BV and five processes of pathogenesis of CV were summarized. According to statistics, there are 123 kinds of main Chinese medicines that can treat BV, 133 kinds of main Chinese medicines that can treat CV, 84 kinds of main Chinese medicines that can treat these two diseases, and the main medicinal components of treating BV and CV are alkaloids, glycosides, phenols. Volatile oil, Lv Yuan acid, flavonoids, pigment, coumarin, etc. The mechanism of traditional Chinese medicine in treating BV and CV: in vitro bacteriostatic experiment, other antimicrobial drug permeability increased, intracellular dissolution leakage, body immunity improved, integrated Chinese and western medicine treatment. Finally, some feasible suggestions are put forward for the treatment of BV and CV with traditional Chinese medicine.
【作者单位】： 陕西理工大学陕西省资源生物重点实验室;陕西理工大学生物科学与工程学院;青海大学农林科学院;汉中天然谷生物科技股份有限公司;
【基金】：陕西省科技厅社会发展项目(2014K13-23) 秦巴山区生物资源综合开发协同创新中心项目(QBXT-Z(Y)-15-2) 陕西理工大学研究生创新基金项目(SLGYCX1721)
【分类号】：R271.9
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1 李风静,黄庆山;炎痒净洗液治疗阴道综合征200例观察[J];实用中医药杂志;1997年05期
2 罗霄山,许家骝;妇女清洗液治疗阴道综合症疗效观察[J];中药药理与临床;2000年06期
，本文编号：2223427
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