揿针配合加味三仁汤治疗复发性阿弗他溃疡（湿热蕴脾证）的临床疗效观察

发布时间：2018-09-06 08:31

【摘要】：目的：通过对揿针配合加味三仁汤治疗复发性阿弗他溃疡(湿热蕴脾证)的临床观察,初步探讨揿针治疗RAU的增效作用及安全性。方法：60例复发性阿弗他溃疡患者全部来自成都中医药大学附属医院口腔科门诊,所有人均符合复发性阿弗他溃疡的中医、西医诊断标准,同时符合中医湿热蕴脾的辨证标准。根据随机分组原理把患者分为治疗组和对照组各30例。对照组予以口服加味三仁汤,治疗组在对照组基础上加用揿针,设定7天为一个疗程。疗程结束后比较两组治疗前后西医局部病损临床疗效(包括愈合时间、溃疡VAS评分、溃疡面积、溃疡个数)、总有效率、及两组使用揿针的不良反应,并在此次治疗结束后进行3个月随访,观察两组患者口腔溃疡的复发情况。最后统计收集到的资料与数据,并采用SPSS17.0作相应分析。结果：(1)治疗前后组内局部症状比较：两组在愈合时间、治疗后第3天、第7天的局部症状(包括溃疡VAS评分、溃疡个数)均比治疗前明显好转(P0.05)；而溃疡面积方面,治疗组在治疗后第3天、第7天均比治疗前明显好转(P0.05)对照组仅在治疗后第7天比治疗前明显好转(P0.05)。(2)治疗后组间局部症状比较：仅在治疗后第7天溃疡VAS评分方面,治疗组明显优于对照组(P0.05)；其他局部症状改善无明显差异(P0.05)。(3)治疗后局部症状改善总有效率比较,两组无明显差异(P0.05)。(4)治疗组和对照组均未见不良反应。(5)3个月复发率比较,治疗组低于对照组。结论：揿针配合加味三仁汤能明显改善复发性阿弗他溃疡(湿热蕴脾证)患者的口腔局部症状,特别是在治疗后第7天对溃疡疼痛的减轻上具有较大优势,并且具有延长复发时间的效果,证明了揿针针刺体穴治疗复发性阿弗他溃疡的确有一定的增效作用,是治疗该病有效的辅助手段。
[Abstract]:Objective: to investigate the efficacy and safety of pressure-acupuncture combined with modified Sanren decoction in the treatment of recurrent aphthous ulcer (dampness and heat accumulation spleen syndrome). Methods Sixty patients with recurrent aphthous ulcer were all from the outpatient department of stomatology department of Chengdu University of traditional Chinese Medicine. All of them were in accordance with the diagnostic criteria of TCM and Western medicine and the standard of syndrome differentiation of dampness and heat accumulation spleen in traditional Chinese medicine. According to the principle of random grouping, the patients were divided into treatment group (n = 30) and control group (n = 30). The control group was given orally modified Sanren decoction, and the treatment group was treated with press needle on the basis of the control group and set 7 days as a course of treatment. After the course of treatment, the clinical efficacy (including healing time, ulcer VAS score, ulcer area, number of ulcers), the total effective rate and the adverse reactions of the two groups were compared before and after treatment. The recurrence of oral ulcer in the two groups was observed after 3 months follow-up. Finally, the collected data and data were collected and analyzed by SPSS17.0. Results: (1) comparison of local symptoms before and after treatment: the local symptoms (including ulcer VAS score, number of ulcers) in the two groups were significantly better than those before and after treatment (P0.05), and the area of ulcer in the two groups was better than that before treatment (P0.05). The treatment group was significantly improved on the 3rd and 7th day after treatment (P0.05). The control group only improved significantly on the 7th day after treatment (P0.05). (2). The local symptoms of the treatment group were compared only in the VAS score of ulcer on the 7th day after treatment. The treatment group was significantly better than the control group (P0.05), other local symptoms improvement had no significant difference (P0.05). (3) after treatment, there was no significant difference between the two groups (P0.05). (4) the treatment group and the control group had no adverse reactions. (5) the recurrence rate of 3 months was higher than that of the control group. The treatment group was lower than the control group. Conclusion: the combination of press acupuncture and modified Sanren decoction can obviously improve the local symptoms of oral cavity in patients with recurrent aphthous ulcer (dampness and heat accumulation spleen syndrome), especially in the relief of ulcer pain on the 7th day after treatment. It also has the effect of prolonging the time of recurrence, which proves that acupuncture at body point has a certain synergistic effect in the treatment of recurrent aphthous ulcer, and it is an effective auxiliary method for the treatment of the disease.
【学位授予单位】：成都中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R276.8

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