滋阴通淋一贯煎合二至丸加减方治疗尿道综合征临床观察

发布时间：2018-09-07 16:47

【摘要】：目的:探讨一贯煎合二至丸加减方治疗更年期尿道综合征的临床疗效。方法:120例患者随机分为两组。中药治疗组60例,给予一贯煎合二至丸加减方治疗,对照组60例,给予尼尔雌醇口服治疗,两组疗程均为12周。观察两组患者症状积分、临床疗效、免疫功能及性激素的变化,观察药物不良反应。结果:治疗12周后,中药治疗组症状积分显著低于对照组(P0.01);中药治疗组总有效率78.33%,显著高于对照组55.0%(P0.01);中药治疗组Ig A、Ig G、Ig M含量均明显高于对照组(P0.01,P0.05);两组患者治疗前后E2、FSH水平比较均无统计学差异(P0.05);两组患者均无明显不良反应。结论:一贯煎合二至丸加减方治疗更年期尿道综合征,能够有效减轻临床症状,提高临床疗效,增强免疫功能,同时还具有类似雌激素的作用,安全性良好,值得推广。
[Abstract]:Objective: to investigate the clinical effect of Yijianhe Erzhi Pill in treating climacteric urethral syndrome. Methods 120 patients were randomly divided into two groups. 60 cases in the traditional Chinese medicine treatment group were treated with Yijianhe Erzhi pills plus or minus prescription, and 60 cases in the control group were treated with nilestriol orally. The course of treatment in both groups was 12 weeks. Symptom score, clinical efficacy, immune function and sex hormone were observed in both groups. Adverse drug reactions were observed. Results: after 12 weeks of treatment, The symptom score of the Chinese medicine treatment group was significantly lower than that of the control group (P0.01), the total effective rate of the Chinese medicine treatment group was 78.33, which was significantly higher than that of the control group (55.0%), the content of Ig Ag G G G M in the Chinese medicine treatment group was significantly higher than that in the control group (P 0.01), and there was no significant difference between the two groups in the level of E2FSH before and after treatment. There was no significant adverse reaction between the two groups (P0.05). Conclusion: the treatment of climacteric urethral syndrome with the decoction of Yijian-Erzhi Pill can effectively relieve the clinical symptoms, improve the clinical efficacy and enhance the immune function. At the same time, it also has the similar effect of estrogen, which is safe and worth popularizing.
【作者单位】：上海市浦东新区公利医院;上海交通大学医学院;
【基金】：上海市卫生局中西医融合发展基金资助项(ZY3-CCCX-3-7001)
【分类号】：R277.5

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