热敏灸联合右归丸治疗脾肾阳虚型卵巢功能早衰的疗效分析

发布时间：2018-09-08 11:01

【摘要】：目的探讨热敏灸联合右归丸治疗脾肾阳虚型卵巢功能早衰(POF)的临床疗效及安全性。方法将142例脾肾阳虚型POF患者分为观察组和对照组,每组71例。观察组采用热敏灸联合右归丸治疗,对照组口服右归丸治疗,疗程均为12周。治疗结束后,比较两组患者临床疗效、Kupperman评分、相关激素[雌二醇(E2)、卵泡刺激素(FSH)、黄体生成素(LH)]水平变化及不良反应发生率。结果观察组总有效率为95.77%,对照组总有效率为77.46%,观察组明显优于对照组(P0.05);治疗前后两组患者的Kupperman评分、相关激素水平均有明显改善(P0.05),但观察组患者Kupperman评分、相关激素水平的改善程度均优于对照组(P0.05)。结论热敏灸联合右归丸治疗脾肾阳虚型POF可缓解临床症状,且安全性高,具有较高的临床应用价值。
[Abstract]:Objective to investigate the clinical efficacy and safety of heat sensitive moxibustion combined with Yougui pill in the treatment of premature ovarian failure with deficiency of spleen and kidney yang. Methods 142 POF patients with deficiency of spleen and kidney yang were divided into observation group and control group with 71 cases in each group. The observation group was treated with heat sensitive moxibustion combined with Yougui pill, and the control group was treated with Yougui pill for 12 weeks. At the end of the treatment, the Kupperman score, the levels of estradiol (E 2), follicle stimulating hormone (FSH),) luteinizing hormone (LH) and the incidence of adverse reactions were compared between the two groups. Results the total effective rate of observation group was 95.77g and the total effective rate of control group was 77.46. The observation group was obviously superior to the control group (P0.05), the Kupperman score and the related hormone level of the two groups were obviously improved before and after treatment (P0.05), but the Kupperman score of the patients in the observation group was better than that of the control group (P0.05). The improvement degree of related hormone level was better than that of control group (P0.05). Conclusion Thermosensitive moxibustion combined with Yougui Pill can relieve the clinical symptoms of POF with deficiency of spleen and kidney yang.
【作者单位】：安徽中医药高等专科学校康保系;安徽省芜湖市中医医院妇产科;
【基金】：2014年度安徽省高校自然科学重点研究基金资助项目(KJ2014A137)
【分类号】：R271.9

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