慢性阻塞性肺疾病气虚证患者血瘀征象的临床研究

发布时间：2018-09-09 20:49

【摘要】：目的:本研究通过对慢阻肺气虚证患者血瘀症状分布规律及血瘀严重程度进行研究分析,探讨慢阻肺血瘀的出现和肺、脾、肾三脏气虚的关系,期指导临床正确认识气虚型慢阻肺患者的血瘀情况,为该病的精确辨治提供依据.方法:收集入住山东中医药大学附属医院的慢阻肺患者,记录其一般信息(性别、年龄、吸烟史、职业、病程)和中医四诊资料,进行辨证分型,选取符合“肺气虚”、“肺脾气虚”、“肺肾气虚”证患者,记录其血常规、D-二聚体、凝血四项等实验室指标,并对患者血瘀症状进行积分。将一般信息、实验室指标、血瘀症状等数据整理后用SPSS统计软件进行统计学分析。结果:本研究共纳入患者100例,其中肺气虚型患者22例、肺脾气虚型患者35例、肺肾气虚型患者43例。经检验,三组证型患者的平均年龄有差异、平均病程有结论:通过研究发现,从肺气虚到肺脾气虚再到肺肾气虚,病情严重程度逐渐增加,血瘀症状逐渐加重,血液粘稠度也逐渐增大,出现血栓的风险也在逐渐增加。血瘀症状积分以及实验室指标能够证实这种差异。
[Abstract]:Objective: to study and analyze the distribution of blood stasis symptoms and the severity of blood stasis in patients with chronic obstructive lung qi deficiency, and to explore the relationship between the occurrence of blood stasis and deficiency of lung, spleen and kidney. To guide the clinical correct understanding of blood stasis in patients with chronic obstructive lung syndrome of qi deficiency, and to provide the basis for accurate differentiation and treatment of the disease. Methods: the patients with COPD admitted to the affiliated Hospital of Shandong University of traditional Chinese Medicine were collected and their general information (sex, age, smoking history, occupation, course of disease) and the four diagnoses of TCM were recorded. In the patients with "deficiency of lung and spleen qi" and "deficiency of lung and kidney qi", the laboratory indexes of blood routine such as D-dimer and coagulation were recorded, and the symptoms of blood stasis were integrated. The data of general information, laboratory indexes and blood stasis were analyzed by SPSS software. Results: a total of 100 patients were included in this study, including 22 patients with deficiency of lung qi, 35 patients with deficiency of lung and spleen qi, 43 patients with deficiency of lung and kidney qi. After examination, the average age of the three syndrome types was different, and the average course of disease was concluded: from deficiency of lung qi to deficiency of lung and spleen qi and then to deficiency of lung and kidney qi, the severity of the disease gradually increased, and the symptoms of blood stasis gradually aggravated. Blood viscosity is also increasing, and the risk of thrombosis is increasing. Blood stasis symptom scores and laboratory indicators can confirm this difference.
【学位授予单位】：山东中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R259

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