中药外用膏剂分期换药治疗肛周脓肿术后患者临床观察
发布时间：2018-09-11 07:57
【摘要】：目的:研究中药外用膏剂分期换药在促进低位肛周脓肿一期根治术术后患者创面愈合的疗效。材料与方法:本研究采用随机对照实验的设计方法。将40例于我院行肛周脓肿一期根治术的患者随机分为2组,每组20例。治疗组在常规治疗的基础上于术后第1d起用三种中药外用膏剂(水调膏、油调膏、一效膏)依次分期换药治疗。对照组在常规治疗的基础上于术后第1d用凡士林纱条联合雷夫奴尔纱条换药治疗。观察两组间创面的愈合情况及安全性指标,对术后第3d、7d、10d第一次换药时创面肉芽生长、疼痛、渗液及分泌物情况做量化积分并进行记录,并对创面愈合时间做记录。用SPSS17.0统计学软件对两组的创面肉芽生长、疼痛、渗液及分泌物积分及创面愈合时间进行统计分析。结果:1.治疗前两组间患者的性别、年龄、病程具有可比性(P0.05)。2.术后第3d,肉芽生长积分、疼痛积分、创面渗液及分泌物积分比较上差异没有统计学意义(P0.05)。3.术后第7d、10d,两组间肉芽生长积分比较有统计学意(P0.05),并且治疗组药物在促进肉芽生长方面优于对照组。术后第7d、10d,两组间疼痛积分比较没有统计学意义(P0.05),提示两组在缓解创面疼痛方面效果差异性不明显。术后第7d,两组间创面渗液及分泌物积分比较差异有统计学意义(P0.05),且治疗组创面渗液及分泌物量大于对照组。术后第10d,组间创面渗液及分泌物积分比较没有统计学意义(P0.05),提示两组在创面渗液及分泌物差异不明显。4.两组在创面愈合时间方面差异有统计学意义(P0.05),并且治疗组在促进创面愈合时间上快于对照组。5.两组在安全性指标观测中未发生不良反应。结论:1.两组换药法在促进低位肛周脓肿一期根治术术后患者创面愈合方面均有效。2.治疗组在创面肉芽生长、愈合时间方面优于对照组,在疼痛方面两组间无差异。提示中药外用膏剂分期换药对行低位肛周脓肿一期根治术患者的创面有促进愈合作用,但对缓解术后创面疼痛的疗效不明确。3.在术后第7d,治疗组创面的渗液及分泌物积分大于对照组,进一步验证了中医学“煨脓长肉”理论。4.中药外用膏剂分期换药在安全性指标观测中未发生不良反应,提示中药外用膏剂分期换药方案安全可靠。
[Abstract]:Objective: to study the effect of external Chinese medicine plaster on promoting wound healing of patients with low perianal abscess after one-stage radical operation. Materials and methods: a randomized controlled trial was used in this study. Forty patients undergoing one stage radical resection of perianal abscess in our hospital were randomly divided into 2 groups with 20 cases in each group. On the first day after operation, the treatment group was treated with three kinds of traditional Chinese medicine plaster (Shuijiao ointment, Youjiao ointment, Yixiao ointment). The control group was treated with vaseline gauze combined with Rayvnur gauze on the first day after operation on the basis of routine treatment. The wound healing and safety indexes were observed. The granulation growth, pain, exudation and secretion of the wound were quantified and recorded on the 3rd day, 7th day and 10th day after operation, and the healing time of the wound was recorded. The granulation growth, pain, exudation, secretion and wound healing time of the two groups were analyzed by SPSS17.0 software. The result is 1: 1. The sex, age and course of disease were comparable between the two groups before treatment (P0.05). On the 3rd day after operation, there was no significant difference in granulation growth score, pain score, wound exudate and secretion score (P0.05). The granulation growth score of the two groups was significantly higher than that of the control group on the 7th and 10th day after operation (P0.05), and the drug in the treatment group was superior to the control group in promoting the granulation growth. There was no significant difference in pain scores between the two groups on the 7th day after operation (P0.05), suggesting that there was no significant difference in pain relief between the two groups. On the 7th day after operation, the difference of wound exudate and secretion between the two groups was statistically significant (P0.05), and the amount of wound exudate and secretion in the treatment group was higher than that in the control group. On the 10th day after operation, there was no significant difference in the score of wound exudate and secretion between the two groups (P0.05), suggesting that there was no significant difference between the two groups in wound exudate and secretion. 4. The difference between the two groups in wound healing time was statistically significant (P0.05), and the treatment group in promoting wound healing time faster than the control group. 5. 5. There was no adverse reaction in the observation of safety index between the two groups. Conclusion 1. The two groups were effective in promoting the wound healing of patients with low perianal abscess after one stage radical operation. The granulation growth and healing time of the treatment group were better than that of the control group, but there was no difference in pain between the two groups. The results suggest that the external application of Chinese medicine plaster can promote wound healing in patients with low perianal abscess by stages, but the curative effect on relieving postoperative wound pain is not clear. 3. On the 7th day after operation, the score of exudation and secretion in the treatment group was higher than that in the control group, which further verified the theory of "simmering pus and long meat" in traditional Chinese medicine. There was no adverse reaction in the observation of safety index of external Chinese medicine plaster by stages, which suggested that the plan of Chinese traditional medicine external plaster change by stages was safe and reliable.
【学位授予单位】：辽宁中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R266
，
本文编号：2236082
[Abstract]:Objective: to study the effect of external Chinese medicine plaster on promoting wound healing of patients with low perianal abscess after one-stage radical operation. Materials and methods: a randomized controlled trial was used in this study. Forty patients undergoing one stage radical resection of perianal abscess in our hospital were randomly divided into 2 groups with 20 cases in each group. On the first day after operation, the treatment group was treated with three kinds of traditional Chinese medicine plaster (Shuijiao ointment, Youjiao ointment, Yixiao ointment). The control group was treated with vaseline gauze combined with Rayvnur gauze on the first day after operation on the basis of routine treatment. The wound healing and safety indexes were observed. The granulation growth, pain, exudation and secretion of the wound were quantified and recorded on the 3rd day, 7th day and 10th day after operation, and the healing time of the wound was recorded. The granulation growth, pain, exudation, secretion and wound healing time of the two groups were analyzed by SPSS17.0 software. The result is 1: 1. The sex, age and course of disease were comparable between the two groups before treatment (P0.05). On the 3rd day after operation, there was no significant difference in granulation growth score, pain score, wound exudate and secretion score (P0.05). The granulation growth score of the two groups was significantly higher than that of the control group on the 7th and 10th day after operation (P0.05), and the drug in the treatment group was superior to the control group in promoting the granulation growth. There was no significant difference in pain scores between the two groups on the 7th day after operation (P0.05), suggesting that there was no significant difference in pain relief between the two groups. On the 7th day after operation, the difference of wound exudate and secretion between the two groups was statistically significant (P0.05), and the amount of wound exudate and secretion in the treatment group was higher than that in the control group. On the 10th day after operation, there was no significant difference in the score of wound exudate and secretion between the two groups (P0.05), suggesting that there was no significant difference between the two groups in wound exudate and secretion. 4. The difference between the two groups in wound healing time was statistically significant (P0.05), and the treatment group in promoting wound healing time faster than the control group. 5. 5. There was no adverse reaction in the observation of safety index between the two groups. Conclusion 1. The two groups were effective in promoting the wound healing of patients with low perianal abscess after one stage radical operation. The granulation growth and healing time of the treatment group were better than that of the control group, but there was no difference in pain between the two groups. The results suggest that the external application of Chinese medicine plaster can promote wound healing in patients with low perianal abscess by stages, but the curative effect on relieving postoperative wound pain is not clear. 3. On the 7th day after operation, the score of exudation and secretion in the treatment group was higher than that in the control group, which further verified the theory of "simmering pus and long meat" in traditional Chinese medicine. There was no adverse reaction in the observation of safety index of external Chinese medicine plaster by stages, which suggested that the plan of Chinese traditional medicine external plaster change by stages was safe and reliable.
【学位授予单位】：辽宁中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R266
，
本文编号：2236082
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