透刺法治疗脑卒中后抑郁的临床研究

发布时间：2018-09-12 15:08

【摘要】：目的:观察透刺法治疗脑卒中后抑郁的临床疗效,评定其对神经功能恢复的影响。方法:将72例来自长春中医药大学第一附属医院针灸疗区、脑病疗区及脑病康复中心的PSD患者,采用随机数字表随机为治疗组和对照组,每组各36例。两组患者皆服用神经内科常规药物为基础治疗。治疗组给予透刺法治疗,对照组给予口服盐酸氟西汀胶囊,疗程均为4周。治疗前后以及3个月后随访时分别用汉密尔顿抑郁量表(HAMD-24项)对两组患者的抑郁症状评定、用美国国立卫生院卒中量表(NIHSS)对患者神经功能缺损情况进行评定。结合量表分值之间的相关性研究以及不同时间的量表分值变化,探讨透刺法治疗PSD的疗效。获取的数据皆采用SPSS19.0统计软件进行数据分析。结果:1.两组患者在年龄、性别、卒中性质、病程方面经统计学处理分析显示均具有可比性。2.治疗前评定患者HAMD评分与NIHSS评分关系提示:患者的抑郁程度和其神经功能情况呈正相关性。3.两种治疗方法皆可以改善脑卒中后患者的抑郁症状及神经功能缺损情况,其中治疗组总有效率为87.88%,对照组总有效率为83.87%,经统计学分析后显示有显著性差异(P0.05),治疗组疗效优于对照组。4.随访时,治疗组在改善患者抑郁症状及神经功能缺损方面远期疗效优于对照组。结论:透刺法在改善脑卒中后抑郁患者的抑郁症状及神经功能缺损情况疗效优于口服盐酸氟西汀胶囊,且远期疗效良好,具有临床推广价值。
[Abstract]:Aim: to observe the clinical effect of penetrating acupuncture on post-stroke depression and to evaluate its effect on recovery of nerve function. Methods: 72 PSD patients from acupuncture and moxibustion treatment area, encephalopathy treatment area and encephalopathy rehabilitation center in the first affiliated Hospital of Changchun University of traditional Chinese Medicine were randomly divided into treatment group (n = 36) and control group (n = 36). The patients in both groups were treated with routine drugs in neurology department. The treatment group was treated with penetration and the control group was given fluoxetine hydrochloride capsule for 4 weeks. The depression symptoms of the two groups were evaluated by Hamilton Depression scale (HAMD-24) before and after treatment and 3 months after follow-up. The neurological impairment was assessed by the stroke scale (NIHSS) of the National Institutes of Health of the United States of America. According to the correlation between the scale scores and the changes of the scale scores at different time, the therapeutic effect of puncture therapy on PSD was discussed. All the acquired data are analyzed by SPSS19.0 statistical software. The result is 1: 1. Two groups of patients in age, sex, nature of stroke, the course of statistical analysis showed that there was comparability. 2. 2. The relationship between HAMD score and NIHSS score before treatment indicated that the degree of depression was positively correlated with the neurological function. Both methods can improve the depressive symptoms and neurological deficit in patients with cerebral apoplexy. The total effective rate of the treatment group was 87.88 and the total effective rate of the control group was 83.87. After statistical analysis, there was significant difference (P0.05). The curative effect of the treatment group was better than that of the control group. 4. At follow-up, the treatment group was superior to the control group in improving depressive symptoms and neurological deficit. Conclusion: the therapeutic effect of penetrating acupuncture on improving depression symptoms and neurological function defects in patients with post-stroke depression is better than that of oral fluoxetine hydrochloride capsule, and it has a good long-term effect and has clinical popularization value.
【学位授予单位】：长春中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R246.6

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