健脾降糖汤治疗肥胖型2型糖尿病痰瘀气虚证临床研究

发布时间：2018-09-14 08:25

【摘要】：目的:观察健脾降糖汤治疗肥胖型2型糖尿病痰瘀气虚证的临床疗效。方法:136例肥胖型2型糖尿病痰瘀气虚证患者随机分为对照组68例,观察组68例。对照组患者采用常规西药治疗,观察组在对照组治疗基础上应用健脾降糖汤治疗。比较两组治疗前后糖化血红蛋白(glycosylated hemoglobin,Hb A1c)、餐后2小时血糖(2 hours postprandial blood glucose,2h PG)、三酰甘油(triglyceride,TG)、空腹血糖(fasting plasma glucose,FPG)、总胆固醇(Total cholesterol,TC)水平、体质量指数及临床症状的变化情况,并评价两组临床疗效。结果:观察组有率为94.12%(64/68),明显高于对照组80.88%(55/68),差异有统计学意义(P0.05)。与治疗前比较,治疗后两组患者Hb A1c、2h PG、FPG、TG、TC水平、体质量指数及中医证候积分均显著降低;且观察组各项观察指标显著低于对照组,差异均有统计学意义(P0.05)。结论:健脾降糖汤治疗肥胖型2型糖尿病痰瘀气虚证患者临床疗效显著,可缓解临床症状,改善血糖、血脂水平,降低体质量指数,提高生存质量。
[Abstract]:Objective: to observe the clinical effect of Jianpi Jiangtang decoction in treating obesity type 2 diabetes mellitus with deficiency of phlegm and qi. Methods 136 cases of obesity type 2 diabetes mellitus were randomly divided into control group (n = 68) and observation group (n = 68). The patients in the control group were treated with routine western medicine, and the patients in the observation group were treated with Jianpi Jiangtang decoction on the basis of the treatment of the control group. The changes of glycosylated hemoglobin (glycosylated hemoglobin,Hb A1c), 2 hours postprandial blood glucose,2h PG), triglyceride (triglyceride,TG), fasting blood glucose (fasting plasma glucose,FPG), total cholesterol (Total cholesterol,TC), body mass index (BMI) and clinical symptoms before and after treatment were compared between the two groups. Results: the rate of the observation group was 94.12% (64 / 68), which was significantly higher than that of the control group (80.88% (55 / 68), P0.05). Compared with before treatment, the levels of Hb A1cU 2 h PG,FPG,TG,TC, body mass index and TCM syndrome score were significantly decreased in the two groups after treatment, and the observed indexes in the observation group were significantly lower than those in the control group, the differences were statistically significant (P0.05). Conclusion: Jianpi Jiangtang decoction is effective in treating obese type 2 diabetes patients with deficiency of phlegm and blood stasis qi, which can relieve clinical symptoms, improve blood glucose, blood lipid level, decrease body mass index and improve quality of life.
【作者单位】：河南大学第一附属医院;
【基金】：国家中医药管理局资助项目(JDZX2012006)
【分类号】：R259

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