补肾疏肝活血调周法治疗多囊卵巢综合征的临床观察

发布时间：2018-10-05 09:38

【摘要】：目的:本研究主要观察补肾疏肝活血调周法治疗肾虚肝郁型多囊卵巢综合征患者的临床疗效,并对其治疗效果做出科学评价,以丰富本病的临床治疗方法,为多囊卵巢综合征的临床治疗提供参考。方法:选取符合本课题标准的PCOS患者32例,用补肾疏肝活血调周法治疗三个月经周期,分别于治疗前和疗程结束后观察患者临床症状(多毛、痤疮、月经不调、肥胖)、妊娠情况、中医证候积分、性激素水平及B超(卵巢多囊样改变)的变化情况,并根据临床综合疗效判定标准评估补肾疏肝活血调周法治疗肾虚肝郁型PCOS的总疗效。结果:补肾疏肝活血调周法治疗PCOS取得以下结果:1.痊愈7例,显效10例,9例有效,6例无效,总有效率达到81.2%。2.治疗后患者临床症状得到明显改善:月经周期缩短,治疗前后差异具有显著性(P0.05),闭经者11例,5例治愈,治愈率达45.5%;治疗后患者痤疮症状明显改善,治疗前后差异具有显著性;多毛18例,无患者治愈,但多毛评分等级有不同程度的下降;治疗后10例不孕患者有3例怀孕;治疗后肥胖患者的BMI较治疗前下降,差异有统计学意义。3.对中医证候积分的影响:中医证候积分治疗后明显降低,治疗前后差异具有显著性。4.对血清性激素水平的影响:治疗后LH、LH/FSH、T的水平较治疗前明显下降,差异具有统计学意义;治疗后FSH变化不明显,无统计学意义。5.卵巢多囊样人数的改变:治疗后卵巢多囊样改变患者的例数降低,治疗前双侧卵巢多囊样改变的患者有17例,单侧卵巢多囊样改变的患者有9例;治疗后双侧卵巢多囊样改变的患者降至11例,单侧卵巢多囊样改变的患者降至6例,治疗前后差异具有显著性。结论:补肾疏肝活血调周法治疗肾虚肝郁型PCOS患者疗效确切,可改善患者月经不调、多毛、痤疮、肥胖等症状,降低中医证候评分,调节PCOS患者内分泌紊乱的状态,改善患者卵巢多囊情况,同时有助于改善患者妊娠。研究证明,补肾疏肝活血调周法值得进一步推广应用。
[Abstract]:Objective: to observe the clinical effect of tonifying kidney, dispersing liver and activating blood circulation and regulating weeks in treating polycystic ovary syndrome with kidney deficiency and liver depression, and to make a scientific evaluation of its therapeutic effect, so as to enrich the clinical treatment methods of this disease. To provide a reference for the clinical treatment of polycystic ovary syndrome. Methods: 32 patients with PCOS who met the standard of this subject were treated with the method of tonifying the kidney, soothing the liver and activating blood circulation for three menstrual cycles. The clinical symptoms of the patients were observed before and after the course of treatment (hirsutism, acne, irregular menstruation). Obesity), pregnancy, TCM syndrome score, sex hormone level and B-ultrasound (ovarian polycystic changes), and according to the clinical comprehensive efficacy criteria to evaluate the treatment of kidney deficiency and liver stagnation of PCOS treatment of the total efficacy of the method of tonifying the kidney, dispersing the liver, activating blood circulation and regulating the week. Results: the treatment of PCOS by tonifying kidney, dispersing liver, activating blood circulation and regulating weeks has obtained the following results: 1: 1. 7 cases were cured, 9 cases were effective and 6 cases were ineffective, the total effective rate was 81.2%. After treatment, the clinical symptoms of the patients were obviously improved: the menstrual cycle was shortened, the difference before and after treatment was significant (P0.05), 11 cases of amenorrhea were cured in 5 cases, the cure rate was up to 45.5%, the symptoms of acne were obviously improved after treatment, and the difference was significant before and after treatment. There were 18 cases of hirsutism, none of them cured, but the score of hirsutism decreased to some extent; after treatment, 3 cases of infertile patients were pregnant; the BMI of obese patients was lower than that of before treatment, the difference was statistically significant. 3. The effect on TCM syndrome integral: TCM syndrome integral significantly decreased after treatment, the difference before and after treatment was significant. 4. Effect on serum sex hormone level: after treatment, the level of LH,LH/FSH,T decreased significantly compared with before treatment, the difference was statistically significant; after treatment, the change of FSH was not obvious, there was no statistical significance. 5. The number of patients with ovarian polycystic changes decreased after treatment, 17 patients with bilateral ovarian polycystic changes and 9 patients with unilateral ovarian polycystic changes before treatment. After treatment, the number of patients with bilateral ovarian polycystic changes decreased to 11 cases, and that of unilateral ovarian polycystic changes decreased to 6 cases. There was significant difference before and after treatment. Conclusion: the therapy of tonifying kidney, dispersing liver and activating blood circulation and regulating weeks is effective in treating PCOS patients with kidney deficiency and liver depression. It can improve the symptoms of irregular menstruation, hirsutism, acne and obesity, reduce the score of TCM syndromes and regulate the state of endocrine disorder in patients with PCOS. Improve the patient's ovarian polycystic condition, at the same time help to improve the patient's pregnancy. The study proved that the method of tonifying kidney, dispersing liver and activating blood circulation is worth further popularizing.
【学位授予单位】：湖北民族学院
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R271.9

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