加味玉屏风散汤剂治疗老年2型糖尿病多汗症患者的临床观察

发布时间：2018-10-09 11:52

【摘要】：目的:观察加味玉屏风散汤剂治疗老年2型糖尿病多汗症患者的临床疗效及安全性。方法:选取2015年1月-2016年6月我院门诊诊治的老年2型糖尿病多汗症患者120例,按随机数字表法分为对照组和观察组,各60例。对照组患者给予糖尿病常规化学药物治疗;观察组患者在对照组基础上加用加味玉屏风散,以水煎制,每次300 mL,早晚各服150 mL,均于餐前1 h服用。两组患者疗程均为1个月。比较两组患者治疗前后的血糖指标[空腹血糖(FPG)、餐后2 h血糖(2 hPG)、糖化血红蛋白(HbA1c)]和中医症状评分,观察临床疗效和不良反应发生情况。结果:治疗前,两组患者的FPG、2 hPG、HbA1c和中医症状评分比较,差异均无统计学意义(P0.05)。治疗后,两组患者的FPG、2 hPG、HbA1c和中医症状评分均较治疗前明显降低,且观察组FPG、HbA1c和中医症状评分明显低于对照组,差异均有统计学意义(P0.05);但两组患者2 hPG比较,差异无统计学意义(P0.05)。观察组患者的总有效率(90.00%)明显高于对照组(70.00%),差异有统计学意义(P0.05)。两组患者均未见明显不良反应发生。结论:加味玉屏风散汤剂治疗老年2型糖尿病多汗症能有效改善患者临床症状,疗效较好且安全性较高。
[Abstract]:Objective: to observe the clinical efficacy and safety of Jiawei Yuping Feng Powder in treating senile type 2 diabetes hyperhidrosis. Methods: 120 elderly patients with type 2 diabetes hyperhidrosis from January 2015 to June 2016 were divided into control group (n = 60) and observation group (n = 60). The patients in the control group were treated with conventional chemical drugs for diabetes, and the patients in the observation group were treated with modified Yupingfeng powder on the basis of the control group, and the patients in the observation group were taken at 1 hour before meal in the morning and evening for 300 mL,. The course of treatment was 1 month in both groups. The blood glucose index [2 hPG), glycosylated hemoglobin (HbA1c)] and TCM symptom score before and after treatment were compared between the two groups [fasting blood glucose 2 h after (FPG), meal], and the clinical efficacy and adverse reactions were observed. Results: before treatment, there was no significant difference in FPG,2 hPG,HbA1c and TCM symptom score between the two groups (P0.05). After treatment, the FPG,2 hPG,HbA1c and TCM symptom scores of the two groups were significantly lower than those before treatment, and the FPG,HbA1c and TCM symptom scores in the observation group were significantly lower than those in the control group (P0.05), but there was no significant difference in 2 hPG between the two groups (P0.05). The total effective rate of the observation group (90.00%) was significantly higher than that of the control group (70.00%), the difference was statistically significant (P0.05). No significant adverse reactions occurred in both groups. Conclusion: Jiawei Yupingfeng Powder decoction can effectively improve the clinical symptoms of senile type 2 diabetes hyperhidrosis, and the efficacy is better and the safety is higher.
【作者单位】：连云港市第一人民医院内分泌科;
【分类号】：R259

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