活血返聪汤干预老年性耳聋的临床研究

发布时间：2018-10-16 20:17

【摘要】：目的:本论文对著名老中医耿鉴庭教授名方活血返聪汤治疗老年性耳聋进行了临床研究,以杞菊地黄丸为对照组,明确其临床疗效,从而为老年性耳聋的临床辨证和选方用药提供更全面的依据和指导原则,为进一步提高老年性耳聋患者的临床疗效作出有益的探讨。方法:将满足纳入标准的60例老年性耳聋患者,随机分成治疗组和对照组,各30例。治疗组口服活血返聪汤治疗,对照组口服杞菊地黄丸,连续治疗四周。治疗结束后观察治疗前后患者的症状体征变化,通过统计学方法比较两组的治疗效果。从而明确活血返聪汤的临床疗效。结果:通过对60例老年性耳聋患者的临床观察,治疗组的治愈率为0%,显效率30%,有效率46.6%,总有效率为76.6%;对照组的治愈率为0%,显效率6.6%,有效率40%,总有效率为46.6%。经统计学分析,两组有显著统计学差异(p=0.0170.05),治疗组临床总体疗效明显优于对照组。结论:活血返聪汤在补肾填精基础上重视活血及开窍药物的使用,符合老年性耳聋的生理病理特点,其治疗老年性耳聋的临床疗效优于临床常用药杞菊地黄丸,能够更有效的缓解和治疗老年性耳聋的常见症状,延缓老年性耳聋病人的听觉衰老过程,提高老年性耳聋病人的生活质量。其组方配伍体现出补肾活血、开窍聪耳是治疗老年性耳聋的有效治法,值得我们进一步探讨。
[Abstract]:Objective: to study the clinical effect of famous old Chinese medicine professor Geng Jianting on the treatment of presbycusis with Huoxue Huicong decoction, taking Qiju Dihuang Pill as the control group. It provides more comprehensive basis and guiding principle for clinical syndrome differentiation and prescription selection of presbycusis, and makes a beneficial discussion for further improving the clinical curative effect of presbycusis patients. Methods: 60 cases of presbycusis were randomly divided into treatment group and control group, 30 cases in each group. The treatment group was treated with Huoxue Huicong decoction and the control group with Qiju Dihuang pills for four weeks. The changes of symptoms and signs before and after treatment were observed, and the therapeutic effects of the two groups were compared by statistical method. So as to determine the clinical efficacy of Huoxue Huicong decoction. Results: through the clinical observation of 60 cases of presbycusis, the cure rate of the treatment group was 0, the markedly effective rate was 30, the effective rate was 46.6, and the total effective rate was 76.6.The cure rate of the control group was 0, the markedly effective rate was 6.6, the effective rate was 400.The total effective rate was 46.6. Statistical analysis showed that there was a significant difference between the two groups (p0.0170.05). The overall clinical efficacy of the treatment group was significantly better than that of the control group. Conclusion: Huoxue Huucong decoction attaches importance to the use of drugs for activating blood circulation and resuscitation on the basis of invigorating kidney and filling essence, which accords with the physiological and pathological characteristics of presbycusis. The clinical effect of Huoxue Huicong decoction in the treatment of presbycusis is better than that of Qiju Dihuang pills, which is a common clinical drug. It can effectively relieve and treat the common symptoms of presbycusis, delay the process of hearing senescence and improve the quality of life of presbycusis patients. The combination of its prescription reflects tonifying the kidney and activating blood circulation, and opening the orifices and ears is an effective method for the treatment of presbycusis, which is worthy of further discussion.
【学位授予单位】：山东中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R276.1

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