王秀霞教授治疗围绝经期功血用药规律的研究

发布时间：2018-10-18 21:07

【摘要】：目的：本研究旨在探索名老中医王秀霞教授治疗围绝经期功血的用药规律,总结出王秀霞教授治疗本病的方法和经验,从而更深入地挖掘名老中医独到的学术思想,为传承名老中医诊治围绝经期功血的经验提供理论支持。方法：收集和整理王秀霞教授临床治疗围绝经期功血的处方。利用Microsoft Exce12007建立资料数据表。按出血期处方与非出血期处方分别将所选处方中的药物及其四气、五味、归经、功效分类分别录入,统计每种药物的使用频次、频率,总结常用药物。根据统计结果,分析王秀霞教授治疗围绝经期功血用药规律,总结治疗经验。结果：1.在出血期的89张处方中,共涉及药味55种,使用频次总计1148次,统计出高频用药11味,包括：龙骨88次,墨旱莲85次,牡蛎80次,白芍80次,苍术79次,地榆76次,阿胶75次,山茱萸68次,夏枯草68次,海螵蛸66次,续断65次。2.在非出血期的43张处方中,共涉及药味49种,使用频次总计488次,统计出高频用药11味,包括：覆盆子37次,杜仲36次,黄芪31次,阿胶29次,墨旱莲26次,苍术24次,白芍24次,夏枯草24次,女贞子24次,太子参22次,山茱萸22次。3.在出血期使用药物中,按药物四气分类频次统计：寒性药506次温性药385次平性药244次；按药物五味分类频次统计分析：甘味药625次苦味药494次酸味药353次涩味药317次；按药物归经分类频次统计：肝胆经928次肾膀胱经640次脾胃经382次；按药物功效分类频次统计：补虚药405次,其次为收涩药359次；补虚药中补血药占补虚药百分比为39.51%补阴药26.91%补阳药23.46%补气药10.12%。4.在非出血期使用药物中,按药物四气分类频次统计：温性药203次平性药132次寒性药124次；按药物五味分类频次统计分析：甘味药355次苦味药183次辛味药125次酸味药119次；按药物归经分类频次统计：肝胆经282次肾膀胱经257次脾胃经229次；按药物功效分类频次统计：补虚药258次,其次为收涩药88次；补虚药中补气药占补虚药百分比为30.62%补血药24.03%补阴药23.64%补阳药21.71%。结论：1.王秀霞教授治疗围绝经期功血出血期的常用药物有：龙骨墨旱莲、牡蛎、白芍、苍术、地榆、阿胶、山茱萸、夏枯草、海螵、续断；非出血期的常用药物有：覆盆子、杜仲、黄芪、阿胶、墨旱莲、苍术、白芍、夏枯草、女贞子、太子参、山茱萸。2.王秀霞教授治疗围绝经期功血的经验总结如下：(1)灵活运用塞流、澄源、复旧三法。(2)从肾肝脾论治。(3)围绝经期功血的主要病机为肝肾阴虚,热扰冲任；脾气虚弱,冲任不固。(4)出血期治疗以滋肾养肝,凉血固冲为主。(5)非出血期以健脾益肾,滋阴养血为主。
[Abstract]:Objective: the purpose of this study was to explore the rule of drug use of Professor Wang Xiuxia in the treatment of peri-menopausal dysfunctional blood, summarize the methods and experiences of Professor Wang Xiuxia in the treatment of this disease, and further explore the unique academic thoughts of famous old Chinese medicine. To provide theoretical support for inheriting the experience of old Chinese medicine in the diagnosis and treatment of peri-menopausal dysfunctional blood. Methods: to collect and arrange the prescriptions of Professor Wang Xiuxia for the treatment of peri-menopausal dysfunctional blood. Make use of Microsoft Exce12007 to build data table. According to the prescription of bleeding period and the prescription of non-bleeding period, the drugs and their four gases, five flavors, meridians and efficacy were recorded separately, the frequency and frequency of use of each drug were counted, and the common drugs were summarized. According to the statistical results, professor Wang Xiuxia in the treatment of perimenopausal dysfunctional blood use law, summed up the treatment experience. The result is 1: 1. In the 89 prescriptions of bleeding period, 55 kinds of medicinal taste were involved, and the total frequency of use was 1148 times. 11 kinds of high frequency drugs were obtained, including 88 keel times, 85 times of Herba hyacinth, 80 times of oyster, 80 times of white peony, 79 times of Atractylodes, 76 times of elm, 75 times of gelatin. Cornus officinalis 68, Prunella subtilis 68, Cuttlebone 66, Dipsacus 65. 2. Among the 43 prescriptions in non-bleeding period, 49 kinds of medicinal flavor were involved, and the frequency of use was 488 times. 11 kinds of high-frequency drugs were obtained, including: raspberry 37 times, Eucommia 36 times, astragalus 31 times, gelatin 29 times, Upland morifolium 26 times, Atractylodes 24 times. Radix Paeoniae Alba 24, Prunella subtilis 24, Ligustrum lucidum 24, Radix Pseudostellariae 22, Fructus Corni 22. 3. In the period of bleeding, according to the frequency statistics of four kinds of drugs: cold drugs 506 times temperature drugs 385 times flat drugs 244 times, according to drug five classification frequency statistical analysis: sweet flavor drugs 625 times bitter drugs 494 times acid drugs 353 times astringent drugs 317 times; According to drug classification frequency statistics: liver and gallbladder passage 928 kidney bladder 640 spleen stomach passage 382 times, according to the drug efficacy classification frequency statistics: tonifying drugs 405 times, followed by the collection of acerbity drugs 359 times; The percentage of blood tonifying drugs to tonifying deficiency drugs was 39.51%, 26.91% and 23.46% respectively. Among the drugs used in the non-bleeding period, according to the frequency statistics of four kinds of drugs: 203 times of mild drugs, 132 times of cold drugs, 124 times of cold drugs according to the five kinds of drugs: 355 times of sweet flavor drugs, 183 times of bitter drugs, 125 times of sour drugs, 119 times of sour drugs; According to the frequency statistics of drug classification, 282 times of liver and gallbladder, 257 times of kidney and bladder, 257 times of spleen and stomach, 258 times of tonifying drugs, 88 times of astringent drugs, according to the classification frequency of drug efficacy; The percentage of tonifying qi drugs in tonifying deficiency drugs was 30.62%, blood tonifying drugs 24.03%, tonifying yin drugs 23.64%, tonifying yang drugs 21.71%. Conclusion 1. Professor Wang Xiuxia's commonly used drugs for the treatment of peri-menopausal dysfunctional bleeding are: Artemisia koraiensis, oysters, white peony, Atractylodes, Ulmus elm, Ejiao, Cornus officinalis, Prunella subtilis, ladyfish, dipsacum, and non-bleeding drugs: raspberry, Eucommia ulmoides, Astragalus, Ejiao, Artemisia, Atractylodes, Radix Paeoniae Alba, Prunella subtilis, Ligustrum lucidum, Radix Pseudostellariae, Fructus Corni. 2. Professor Wang Xiuxia's experience in the treatment of peri-menopausal dysfunctional blood is summarized as follows: (1) flexible use of the three methods of blockage, Chengyuan, and reversion. (2) treatment from kidney, liver and spleen. (3) the main pathogenesis of peri-menopausal dysfunctional blood is liver and kidney yin deficiency, heat disturbance, weak temper, and weak temper. (4) the treatment of bleeding period is to nourish the kidney and nourish the liver, cool the blood to strengthen the liver, and (5) to invigorate the spleen and invigorate the kidney, nourish the yin and nourish the blood.
【学位授予单位】：黑龙江中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R249;R271.9

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