中药熏蒸治疗失眠的系统评价

发布时间：2018-11-07 21:37

【摘要】：目的:系统评价中药熏蒸治疗失眠的有效性及安全性。方法:按Cochrane系统评价方法,计算机检索Cochrane Library、MEDLINE、EMBASE、Pub Med、中国生物医学文献数据库(CBM)、万方资源知识服务平台(WF)、中国知网(CNKI)、维普期刊资源整合服务平台(VIP)等数据库中有关中药熏蒸治疗失眠的随机对照试验,按照纳入和排除标准筛选文献、提取资料并评价所纳入的研究,运用Rev Man 5.2软件进行系统分析。结果:5篇研究满足纳入标准,共计436例受试者。结果显示中药熏蒸治疗失眠在总有效率方面优于对照组(RR=1.25,95%CI 1.11~1.42);在缩短睡眠潜伏期方面,治疗组优于对照组(MD=-14.02,95%CI-17.49~-10.56);改善睡眠时间方面,治疗组优于对照组(MD=79,95%CI 64.49~93.50);改善睡眠效率方面,治疗组优于对照组(MD=27.53,95%CI25.02~30.04)。结论:中药熏蒸治疗失眠具有较好的疗效,但鉴于纳入的研究质量较低,仍需要更多设计合理的、随机方法正确的、多中心的、大样本的、高质量的随机对照临床试验予以进一步验证。
[Abstract]:Objective: to evaluate the efficacy and safety of traditional Chinese medicine fumigation for insomnia. Methods: according to the evaluation method of Cochrane system, the Cochrane Library,MEDLINE,EMBASE,Pub Med, Chinese biomedical literature database, (CBM), Wanfang resource knowledge service platform, (WF), China knowledge Network (CNKI), was searched by computer. A randomized controlled trial of traditional Chinese medicine fumigation for insomnia was conducted in the database of (VIP) and other databases. The literature was screened according to the criteria of inclusion and exclusion, and the data were extracted and evaluated. System analysis was carried out by using Rev Man 5.2 software. Results: a total of 436 subjects met the inclusion criteria in 5 studies. The results showed that the total effective rate of TCM fumigation was better than that of the control group (RR=1.25,95%CI 1.111.42), and the treatment group was superior to the control group (MD=-14.02,95%CI-17.49~-10.56) in shortening the sleep latency. In improving sleep time, the treatment group was superior to the control group (MD=79,95%CI 64.49 ~ 93.50), and the treatment group was superior to the control group (MD=27.53,95%CI25.02~30.04) in improving sleep efficiency. Conclusion: traditional Chinese medicine fumigation has a better curative effect on insomnia, but in view of the low quality of the studies involved, it is still necessary to design more reasonable, random, multicenter and large sample methods. High-quality randomized controlled clinical trials were further validated.
【作者单位】：宁波市中医院;
【基金】：国家中医药管理局科研基金项目(SATCM-2015-BZ(334)
【分类号】：R256.23

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