调和营卫法治疗慢性心力衰竭气虚血瘀证的临床研究

发布时间：2018-11-16 08:22

【摘要】：目的:观察调和营卫法治疗慢性心力衰竭气虚血瘀证的临床疗效,并对该病病因病机以及治法方药进行初步探讨。方法:病例选取来自山东省中医院心内科门诊和病房,参照2007年12月中华医学会心血管病学分会《慢性心力衰竭诊断治疗指南》,经诊断为慢性心力衰竭气虚血瘀证患者60例,采取简单随机方法,分为对照组和试验组,每组30例。两组均给予西药常规治疗,对照组予自拟益气活血方,试验组在服用自拟益气活血方的基础上加用调和营卫的桂枝汤。服药4周后,观察两组治疗前后Lee氏心力衰竭症状积分、心功能分级、中医证候积分、心率变异性(HRV)、左心室射血分数(LVEF)、实验室检查指标等的变化。结果:治疗4周后,治疗后两组在Lee氏心力衰竭症状积分、心功能分级、中医症候积分、心率变异性(HRV)、左心室射血分数(LVEF)、实验室指标等方面均能有效改善,经检验具有统计学差异(P0.01或0.05),且试验组显著优于对照组,差异具有统计学意义(P0.01或0.05)。结论:调和营卫法对慢性心力衰竭气虚血瘀证患者的病变治疗有确切的临床疗效,能有效改善患者的症状,提高患者的生活质量。
[Abstract]:Objective: to observe the clinical effect of tonifying Ying Wei method in treating chronic heart failure with qi deficiency and blood stasis, and to explore the etiology and pathogenesis of the disease and the prescription of treatment. Methods: 60 patients with chronic heart failure were selected from the outpatient department and ward of Department of Cardiology, Shandong traditional Chinese Medicine Hospital, according to the guidelines for the diagnosis and treatment of chronic Heart failure (CHF) in December 2007, which were diagnosed as Qi deficiency and Blood stasis Syndrome (CHF). A simple randomized method was adopted and divided into control group and experimental group with 30 cases in each group. Both groups were given routine treatment of western medicine, the control group was given self-prescription of Yiqi and Huoxue, and the experimental group was treated with Guizhi decoction of tonifying Ying-wei on the basis of taking self-prescribed prescription of Yiqi and Huoxue. After taking medicine for 4 weeks, the changes of Lee's heart failure symptom score, cardiac function grading, TCM syndrome score, left ventricular ejection fraction (LVEF),) of heart rate variability (HRV) were observed before and after treatment. Results: after 4 weeks of treatment, Lee's heart failure symptom score, cardiac function grading, TCM symptom score, left ventricular ejection fraction (LVEF),) laboratory index of heart rate variability (HRV) (HRV), were effectively improved in the two groups. The difference was statistically significant (P0.01 or 0.05), and the test group was significantly better than the control group (P0.01 or 0.05). Conclusion: the treatment of chronic heart failure with Qi-deficiency and blood-stasis syndrome by the method of reconciling Ying Wei has definite clinical curative effect, which can effectively improve the symptoms of the patients and improve the quality of life of the patients.
【学位授予单位】：山东中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R259

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