基于中医体质因素对海南地区特应性皮炎的相关临床研究

发布时间：2018-11-17 20:08

【摘要】：目的:研究中医体质类型与海南地区特应性皮炎发病的相关性以及不同中医证候、性别、年龄、病情程度等与特应性皮炎患者中医体质类型的相关性,初步探讨中医体质理论在海南地区特应性皮炎防治中的作用。方法:参照权威文献,并结合导师、专家意见制定《知情同意书》、《临床观察表》、《SCORAD评分系统表》和《特应性皮炎中医体质调查表》,对患者进行体质类型和相关体质因素的调查。并对测评所得结果分别根据性别、年龄、病情程度、中医证型等进行统计,分析各种体质类型和体质因素与特应性皮炎发病的关系,提出海南地区特应性皮炎的防治原则。结果:1、共收集特应性皮炎病例90例,其中女性患者41例,占45.6%;男性患者49例,占54.4%,年龄最小1岁,最大29岁,病程最短为2年,最长26年,平均病程8.26±6.583年,其中病程中位数为6年;2、海南地区特应性皮炎患者中医体质调查中,特禀质、阴虚质、阳虚质、气虚质、痰湿质、湿热质、血瘀质、气郁质、平和质分别占30.8%、16.8%、8.1%、5.9%、5.9%、5.4%、2.2%、6.5%、18.4%;3、90例特应性皮炎患者中,单一体质有44例,占总病例数的49%,平均年龄在9.98±6.267岁;兼夹体质46例,占总病例数的51%,平均年龄在12.47±7.282岁;4、海南地区特应性皮炎患者中,阳虚质、血瘀质气郁质、平和质在男性特应性皮炎患者中分别占6.1%、2%、47%,在女性患者中分别占29.3%、36.6%、26.8%;阳虚质、血瘀质气郁质在女性特应性皮炎患者中的百分比较男性分别增加23.2%、34.6%,平和质在男性特应性皮炎患者中的百分比较女性增加20.2%,并且均具有统计学意义;5、海南地区特应性皮炎8岁以下患儿单一体质占58.5%,两种兼夹体质占29.8%;中医体质类型调查中以特禀质、平和质、阴虚质居多,分别占34.8%、27.3%及21.2%;阳虚质、气虚质、湿热质血瘀质气郁质在青春期及成人期特应性皮炎患者中的比例明显高于婴幼儿及儿童期,并且具有统计学意义;6、90例特应性皮炎患者中,轻中度患者71例,占38.4%;重度患者114例,占61.6%;7、90例特应性皮炎患者中,中医证属风湿蕴肤58例,占64%,血虚风燥32例,占36%。结论:1、海南地区特应性皮炎患者中医体质类型出现的频率依次为特禀质平和质阴虚质阳虚质气郁质气虚质=痰湿质湿热质血瘀质。2、海南地区特应性皮炎发病率较高,多幼年即发病,持续时间长,年龄及病程跨度大,平均病程长。在3-11岁年龄段内临床症状表现得尤为突出。3、随着年龄的增长,特应性皮炎患者单一体质逐渐减少,兼夹体质逐渐增多。4、海南地区特应性皮炎女性患者血瘀体质、阳虚体质、气郁体质明显多于男性,而男性平和质远高于女性。儿童体质较为单纯,以特禀质最多,平和质其次。随着年龄增长,平和质逐渐减少。5、在病情程度、中医证型与中医体质类型的分析中,经统计学研究,差异均不具有统计学意义,不能认为不同程度内、不同中医证型内各种体质类型的分布是不同的。6、海南地区独特的地理和人文环境与患者中医体质类型的形成有着密切关系。
[Abstract]:Objective: To study the correlation between the type of TCM constitution and the incidence of atopic dermatitis in Hainan, and the correlation between the symptoms, sex, age, degree of disease of TCM and the type of TCM constitution in the patients with atopic dermatitis. The effect of the traditional Chinese medicine constitution theory in the prevention and treatment of atopic dermatitis in Hainan area is discussed. Methods: With reference to the authoritative literature, and in combination with the tutor, the expert's opinion, the "Informed Consent Form>, the , the and the <. The relationship between physical and physical factors and the pathogenesis of atopic dermatitis was analyzed according to the sex, age, degree of disease and the type of TCM, and the prevention and treatment of atopic dermatitis in Hainan area were put forward. Results: A total of 90 cases of atopic dermatitis were collected. Among them, 41 cases (45.6%) were female (54. 4%), the youngest was 1, the maximum was 29, the course of the course was 2 years, the longest was 26 years, the average course was 8.26 to 6.583 years, and the median course of the course was 6 years; 2. In the investigation of TCM constitution of the patients with atopic dermatitis in the region of Hainan, the intrinsic quality, yin deficiency, yang-yang, qi-deficiency, phlegm-dampness, heat and heat, blood stasis, qi-stagnation, and peace were 30.8%, 16. 8%, 80.1%, 5.9%, 5.9%, 5.4%, 2.2%, 6.5% and 18.4%, respectively. In the patients with atopic dermatitis, 44 of the 90 patients with atopic dermatitis accounted for 49% of the total number of cases, the average age was 9.98%, the average age was 9.98%, and the average age was in the range of 12. 47 to 7.282; and 4. In the patients with atopic dermatitis in Hainan, yang-yang and blood-stasis and qi-stagnation were found in the patients with atopic dermatitis. The percentage of mild and moderate in the patients with atopic dermatitis was 60.1%, 2%, and 47%, respectively, in the female patients, the percentage of male and female patients increased by 2.3%, 36. 6%, 26. 8%, respectively. The percentage of the patients with yang-deficiency, blood-stasis and qi-stagnation in the patients with atopic dermatitis increased by 2.3. 2%, 34.6%, respectively. The percentage of mild and moderate in the patients with atopic dermatitis increased by 20. 2%, and all of them had statistical significance; 5. The single body constitution of the children under the age of 8 was 58. 5% in the area of Hainan, 29. 8% of the two cases, and the intrinsic quality, the peace and the quality were found in the constitution type investigation of the traditional Chinese medicine. The majority of yin-deficiency, accounting for 34.8%, 27.3% and 25.2%, respectively; the proportion of yang-yang, qi-deficiency, damp-heat and blood-stasis and qi-stagnation in the patients with adolescent and adult-related atopic dermatitis was significantly higher than that of infants and children, and it was of statistical significance; in 6, 90 patients with atopic dermatitis, Among the patients with mild and moderate, 71 cases (38. 4%), 114 (61.6%) of severe patients (60.6%), and 7 (90) patients with atopic dermatitis (TCM), 58 cases (64%) and 32 (36%) of blood-deficiency wind. Conclusion: 1. The frequency of TCM constitution type in the patients with atopic dermatitis in Hainan area is of the intrinsic quality, the quality of Qi and Qi, and the blood stasis of the damp-heat of the phlegm-wet type. The incidence of atopic dermatitis in the area of Hainan is high, the onset and the duration of the disease in Hainan are long. The age and duration of the disease are long, and the average course of the disease is long. in that 3-11-year-old age group, the clinical symptoms are particularly prominent. 3, with the increase of age, the single body constitution of the patients with atopic dermatitis is gradually decrease, and the body constitution is gradually increasing. Men's peace is much higher than that of women. The physical constitution of children is simple, and the most important and peaceful nature of the children is the second. with the increase of age and the gradual decrease of the quality of the traditional Chinese medicine, 5, in the analysis of the degree of disease, the syndrome of the Chinese medicine and the type of the constitution of the traditional Chinese medicine, the statistical study and the difference have no statistical significance. The unique geographical and human environment in Hainan is closely related to the formation of Chinese traditional Chinese medicine.
【学位授予单位】：湖南中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R275.9

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