助卵1号汤联合外治法治疗排卵障碍性不孕症肾虚肝郁证临床观察
发布时间：2018-11-18 21:30
【摘要】：目的:观察助卵1号汤联合外治法治疗排卵障碍性不孕症肾虚肝郁证月经表现、全身症状表现、基础体温、卵泡、内膜发育及妊娠情况,并探讨其作用机理。方法:收集排卵障碍性不孕症肾虚肝郁证患者60例,治疗组30例,予助卵1号汤联合推拿、拔罐、艾灸治疗;对照组30例,予氯米芬及人绒毛膜促性腺激素治疗。3个月经周期为一个疗程,连续治疗1-2个疗程,记录两组患者治疗前后临床症状、月经情况、基础体温、卵泡、内膜发育及妊娠情况。结果:治疗组总有效率为86.67%,排卵率为67.32%,妊娠率56.67%,对照组总有效率为73.33%,排卵率为69.27%,妊娠率30.00%,两组患者治疗后疗效比较差异有统计学意义(P0.05),排卵率比较差异无统计学意义(P0.05),妊娠率比较差异有统计学意义(P0.05),治疗组在总有效率、妊娠率方面优于对照组。治疗后两组患者中医证候总积分,两组比较有显著统计学意义(P0.01),两组在治疗前后的比较也有统计学意义(P0.01),治疗组优于对照组。治疗后两组患者月经症状总积分,治疗组和对照组相比有显著统计学意义(P0.05),两组在治疗前后的比较有显著统计学意义(P0.01),治疗组优于对照组。两组治疗后子宫内膜厚度比较差异有显著统计学意义(P0.01),治疗组优于对照组。两组治疗后最大优势卵泡直径比较差异无统计学意义(P0.05),两组在治疗前后的比较有显著统计学意义(P0.01)。两组治疗后基础体温比较差异无统计学意义(P0.05)。结论:助卵1号汤联合推拿、拔罐、艾灸是治疗排卵障碍性不孕症肾虚肝郁证的有效方法。治疗组和对照组均能通过增加排卵率和妊振率及改善临床症状和月经情况以达治疗目的,在增加患者妊振率、增加子宫内膜厚度、改善临床症状及总疗效方面的比较来看,治疗组的综合疗效均优于对照组。助卵1号汤联合推拿、拔罐、艾灸在治疗过程中未发现毒副作用及不良反应,安全可靠,值得临床推广应用。
[Abstract]:Objective: to observe the menstrual manifestations, systemic symptoms, basal body temperature, follicle, intimal development and pregnancy of ovulation disorder infertility treated by ZY-1 decoction combined with external treatment, and to explore its mechanism. Methods: 60 patients with kidney deficiency and liver depression were collected and 30 patients in treatment group were treated with ZY-1 decoction combined with massage, cupping and moxibustion. The control group (30 cases) was treated with clomiphene and human chorionic gonadotropin (HCG). Endometrial development and pregnancy. Results: the total effective rate, ovulation rate and pregnancy rate of the treatment group were 86.67 and 67.32, respectively. The total effective rate of the control group was 73.33, the ovulation rate was 69.27, and the pregnancy rate was 30.00. Two groups of patients after treatment were statistically significant difference in curative effect (P0.05), ovulation rate difference was not statistically significant (P0.05), pregnancy rate difference was statistically significant (P0.05), treatment group in the total effective rate, The pregnancy rate was better than that of the control group. After treatment, the total score of TCM syndromes in the two groups was statistically significant (P0.01), the comparison between the two groups before and after treatment was also statistically significant (P0.01), the treatment group was better than the control group. After treatment, the total score of menstrual symptoms in the two groups, treatment group and control group compared with significant statistical significance (P0.05), the two groups before and after treatment has significant statistical significance (P0.01), the treatment group is better than the control group. There was significant difference in endometrial thickness between the two groups after treatment (P0.01), the treatment group was superior to the control group. There was no significant difference in the diameter of the largest dominant follicle between the two groups after treatment (P0.05), and there was significant difference between the two groups before and after treatment (P0.01). There was no significant difference in basic body temperature between the two groups after treatment (P0.05). Conclusion: ZY-1 decoction combined with massage, cupping and moxibustion is an effective method to treat the syndrome of kidney deficiency and liver depression. Both the treatment group and the control group could increase ovulation rate and pregnancy induced vibration rate, and improve the clinical symptoms and menstrual conditions in order to achieve the purpose of the treatment, in increasing the pregnancy induced vibration rate, increasing the endometrial thickness, improving the clinical symptoms and overall curative effect. The comprehensive curative effect of the treatment group was better than that of the control group. No toxic side effects and adverse reactions were found in the treatment of ZY-1 decoction combined with massage, cupping and moxibustion. It is safe and reliable and worthy of clinical application.
【学位授予单位】：湖南中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R271.14
[Abstract]:Objective: to observe the menstrual manifestations, systemic symptoms, basal body temperature, follicle, intimal development and pregnancy of ovulation disorder infertility treated by ZY-1 decoction combined with external treatment, and to explore its mechanism. Methods: 60 patients with kidney deficiency and liver depression were collected and 30 patients in treatment group were treated with ZY-1 decoction combined with massage, cupping and moxibustion. The control group (30 cases) was treated with clomiphene and human chorionic gonadotropin (HCG). Endometrial development and pregnancy. Results: the total effective rate, ovulation rate and pregnancy rate of the treatment group were 86.67 and 67.32, respectively. The total effective rate of the control group was 73.33, the ovulation rate was 69.27, and the pregnancy rate was 30.00. Two groups of patients after treatment were statistically significant difference in curative effect (P0.05), ovulation rate difference was not statistically significant (P0.05), pregnancy rate difference was statistically significant (P0.05), treatment group in the total effective rate, The pregnancy rate was better than that of the control group. After treatment, the total score of TCM syndromes in the two groups was statistically significant (P0.01), the comparison between the two groups before and after treatment was also statistically significant (P0.01), the treatment group was better than the control group. After treatment, the total score of menstrual symptoms in the two groups, treatment group and control group compared with significant statistical significance (P0.05), the two groups before and after treatment has significant statistical significance (P0.01), the treatment group is better than the control group. There was significant difference in endometrial thickness between the two groups after treatment (P0.01), the treatment group was superior to the control group. There was no significant difference in the diameter of the largest dominant follicle between the two groups after treatment (P0.05), and there was significant difference between the two groups before and after treatment (P0.01). There was no significant difference in basic body temperature between the two groups after treatment (P0.05). Conclusion: ZY-1 decoction combined with massage, cupping and moxibustion is an effective method to treat the syndrome of kidney deficiency and liver depression. Both the treatment group and the control group could increase ovulation rate and pregnancy induced vibration rate, and improve the clinical symptoms and menstrual conditions in order to achieve the purpose of the treatment, in increasing the pregnancy induced vibration rate, increasing the endometrial thickness, improving the clinical symptoms and overall curative effect. The comprehensive curative effect of the treatment group was better than that of the control group. No toxic side effects and adverse reactions were found in the treatment of ZY-1 decoction combined with massage, cupping and moxibustion. It is safe and reliable and worthy of clinical application.
【学位授予单位】：湖南中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R271.14
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1 张娅;黄俊山;吴松鹰;李t熲，
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