334例大肠癌中医证候及其相关因素的回顾性研究
发布时间：2018-11-19 07:41
【摘要】：目的:通过回顾性研究,总结大肠癌临床特点分布情况,探索大肠癌中医证候分布规律,并进一步探讨大肠癌与相关因素的相关性,加强对大肠癌的认识,为大肠癌辨证论治提供理论依据,指导临床治疗。方法:首先设计大肠癌临床信息采集表,收集符合纳入标准的334例大肠癌患者的临床资料,对其进行中医辨证,整理信息采集表,建立数据库,运用统计学方法描述大肠癌临床资料的分布情况,总结大肠癌中医证候的分布规律,探索大肠癌与个人一般情况、临床特点、肿瘤生物特性、治疗情况等资料之间的关系。结果:1、在334例病例中,平均年龄为62.46±12.740,50岁以上84.4%;男女比例为1.32:1;广西籍79.6%;汉族58.7%,壮族29.6%,其他少数民族11.7%;中学文化程度近50%;离退休及无业合计超过50%;饮酒者超过50%,吸烟者达到40%。2、肿瘤病灶位于直肠者占45.2%;管状腺癌占80.8%,中分化有62.6%;Ⅲ期与Ⅳ期总患病率和Ⅰ期与Ⅱ期总患病率有统计学差异(P0.05);肿瘤转移者占60.2%,远处转移中,肝转移者53.6%。3、从治疗情况来看,接受化疗者占34.1%,接受手术者占50%。4、从临床特点来看,最短病程为1天,最长病程达17年,中位病程为6个月。入院主诉中腹痛、便血、大便习性改变共占60.8%,体征中腹部疤痕、腹部包块、腹部压痛均占50%以上。有177例患者合并他病,其中胃肠息肉占43.0%。5、从证型分布情况看,6种证型构成比依次是湿热蕴结证(26.6%)脾肾阳虚证(16.8%)瘀毒内阻证(16.6%)脾胃虚弱证(14.7%)气血亏虚证(14.1%)肝肾阴虚证(11.4%),经统计学分析,湿热蕴结证是临床最常见的证型(P0.05)。其余5种证型分布无显著性差异(P0.05)。6、大肠癌证型与性别、年龄、婚姻、文化程度、职业、合并他病、肿瘤部位、病理类型、分化程度无明显相关性(P0.05),与病理分期、肿瘤转移、手术、化疗、病例来源、病程存在相关性(P0.05)。结论:1、大肠癌发病以老年患者为主,男性多于女性;籍贯以广西籍为主,民族以汉族多见,其次是壮族;文化程度集中在中学;职业以离退休为主;吸烟者与饮酒者均占较大比例。2、肿瘤发病部位以直肠最常见;管状腺癌在病理类型中最多见,其分化程度集中在中分化;就病理分期、肿瘤转移情况而言,我院收治患者以中晚期为主。3、手术仍是大肠癌最主要的治疗方式。4、腹痛、便血、大便习惯改变、腹内包块是大肠癌的主要辨病依据。合并疾病中胃肠息肉最多见。5、最常见的证型是湿热蕴结证,脾肾阳虚证也占较高比例。6、大肠癌患者的性别、年龄、婚姻、文化程度、职业、合并他病、肿瘤部位、病理类型、分化程度不会影响大肠癌证型的分布,病理分期、肿瘤转移、手术、化疗、病例来源、病程等会影响大肠癌证型的分布。
[Abstract]:Objective: to summarize the distribution of clinical characteristics of colorectal cancer, explore the distribution of TCM syndromes of colorectal cancer, and further explore the correlation between colorectal cancer and related factors, and strengthen the understanding of colorectal cancer. To provide a theoretical basis for the treatment of colorectal cancer based on syndrome differentiation, guiding clinical treatment. Methods: first of all, we designed the clinical information collection table of colorectal cancer, collected the clinical data of 334 patients with colorectal cancer according to the inclusion criteria, differentiated the symptoms and signs of TCM, sorted out the information collection table, and established a database. The distribution of clinical data of colorectal cancer was described by statistical method. The distribution of TCM syndromes of colorectal cancer was summarized, and the relationship between colorectal cancer and individual general situation, clinical characteristics, tumor biological characteristics and treatment was explored. Results: (1) in 334 cases, the average age was 62.46 卤12.740 ~ 50 years old, the ratio of male to female was 1.32: 1, the nationality of Guangxi was 79.66.The Han nationality was 58.7%, the Zhuang nationality was 29.6 and the other minorities were 11.775. The total number of alcohol drinkers was more than 50, the smokers reached 40.2, the tumors were located in the rectum 45.2, the tubular adenocarcinoma was 80.8, the middle differentiation was 62.6; The total prevalence of stage 鈪，
本文编号：2341586
[Abstract]:Objective: to summarize the distribution of clinical characteristics of colorectal cancer, explore the distribution of TCM syndromes of colorectal cancer, and further explore the correlation between colorectal cancer and related factors, and strengthen the understanding of colorectal cancer. To provide a theoretical basis for the treatment of colorectal cancer based on syndrome differentiation, guiding clinical treatment. Methods: first of all, we designed the clinical information collection table of colorectal cancer, collected the clinical data of 334 patients with colorectal cancer according to the inclusion criteria, differentiated the symptoms and signs of TCM, sorted out the information collection table, and established a database. The distribution of clinical data of colorectal cancer was described by statistical method. The distribution of TCM syndromes of colorectal cancer was summarized, and the relationship between colorectal cancer and individual general situation, clinical characteristics, tumor biological characteristics and treatment was explored. Results: (1) in 334 cases, the average age was 62.46 卤12.740 ~ 50 years old, the ratio of male to female was 1.32: 1, the nationality of Guangxi was 79.66.The Han nationality was 58.7%, the Zhuang nationality was 29.6 and the other minorities were 11.775. The total number of alcohol drinkers was more than 50, the smokers reached 40.2, the tumors were located in the rectum 45.2, the tubular adenocarcinoma was 80.8, the middle differentiation was 62.6; The total prevalence of stage 鈪，
本文编号：2341586
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