穴位埋线配合隔姜灸治疗脾肾阳虚型慢性疲劳综合征的疗效分析及其对T淋巴细胞亚群和NK细胞活性的影响

发布时间：2018-11-27 12:07

【摘要】：目的:观察穴位埋线配合隔姜灸与常规针刺对比治疗脾肾阳虚型慢性疲劳综合征的临床疗效差异及其对T淋巴细胞亚群和自然杀伤细胞(NK)细胞活性的影响。方法:将60例脾肾阳虚型慢性疲劳综合征患者随机分为埋线隔姜灸组与常规针刺组,每组30例。埋线隔姜灸组采用穴位埋线配合隔姜灸治疗,穴位埋线穴取关元、肾俞、脾俞、足三里、气海,每周治疗1次;隔姜灸穴取关元、气海、足三里,每3天治疗1次,均连续1个月。常规针刺组采用常规针刺,穴取关元、肾俞、脾俞、足三里、气海,每天治疗1次,每周治疗6次,休息1 d,连续1个月。观察两组患者治疗前后的临床症状积分、疲劳量表-14积分、疲劳评定量表积分、实验室指标及临床疗效。结果:(1)两组治疗后临床症状积分、疲劳量表-14积分和疲劳评定量表积分均较本组治疗前降低,差异均有统计学意义(均P0.05);治疗后,埋线隔姜灸组临床症状积分、疲劳量表-14积分和疲劳评定量表积分均低于常规针刺组,差异均有统计学意义(均P0.05);(2)两组治疗后血清CD_4~+/CD_8~+、NK%、CD_3~+%、CD_4~+%均高于治疗前,差异均有统计学意义(均P0.05);治疗后埋线隔姜灸组血清CD_4~+/CD_8~+、CD_3~+%、CD_4~+%均高于常规针刺组,差异均有统计学意义(均P0.05);(3)治疗后,埋线隔姜灸组总有效率为96.7%(29/30),常规针刺组总有效率为93.3%(28/30),差异无统计学意义(P0.05)。结论:穴位埋线配合隔姜灸能够有效改善症状,调节脾肾阳虚型慢性疲劳综合征患者T淋巴细胞亚群水平及NK细胞活性,是治疗脾肾阳虚型慢性疲劳综合征的有效方法。
[Abstract]:Objective: to observe the difference of clinical effect of acupoint embedding with ginger separated moxibustion and routine acupuncture in treating chronic fatigue syndrome with deficiency of spleen and kidney yang and its effect on T lymphocyte subsets and (NK) cell activity of natural killer cells. Methods: 60 cases of chronic fatigue syndrome with deficiency of spleen and kidney yang were randomly divided into two groups: moxibustion group and routine acupuncture group, 30 cases in each group. The ginger-separated moxibustion group was treated with acupoint embedding combined with ginger-separated moxibustion, and the acupoint embedding points were treated once a week, including Guanyuan, Shenshu, Pi Yu, Zusanli and Qihai. Ginger-separated moxibustion points take Guan Yuan, Qi Hai, Zusanli, treated once every 3 days, continuously for 1 month. The routine acupuncture group was treated with routine acupuncture, the points were collected from Guan Yuan, Shen Yu, Pi Yu, Zusanli, Qi Hai, treated once a day, 6 times a week, rest for 1 day for 1 month. The clinical symptom score, fatigue scale-14 integral, fatigue rating scale score, laboratory index and clinical efficacy were observed before and after treatment. Results: (1) the scores of clinical symptoms, fatigue scale-14 and fatigue rating scale were significantly lower in the two groups than before treatment (P0.05). After treatment, the clinical symptom score, fatigue scale-14 integral and fatigue assessment scale integral in the ginger-separated moxibustion group were lower than those in the routine acupuncture group, the differences were statistically significant (P0.05). (2) the ratio of serum CD_4~ / CD_8~, NK%,CD_3~% and CD_4~% in two groups were significantly higher than that before treatment (P0.05). After treatment, the serum CD_4~ / CD_8~, CD_3~% and CD_4~% in the ginger-separated moxibustion group were significantly higher than those in the routine acupuncture group (P0.05). (3) after treatment, the total effective rate was 96.7% (29 / 30) in moxibustion group and 93.3% (28 / 30) in routine acupuncture group, the difference was not statistically significant (P0.05). Conclusion: catgut embedding at acupoints combined with ginger-separated moxibustion can effectively improve the symptoms, regulate the level of T lymphocyte subsets and the activity of NK cells in patients with chronic fatigue syndrome of spleen and kidney yang deficiency, and is an effective method for treating chronic fatigue syndrome with deficiency of spleen and kidney yang.
【作者单位】：日照市中医医院针灸推拿二科;
【分类号】：R246.9

【相似文献】