归脾汤加减内外合治心脾两虚型失眠的临床研究
[Abstract]:The purpose of this study is to make a clinical observation on the deficiency type insomnia of the spleen and the spleen, which is combined with the addition and subtraction of the spleen and the stomach, in order to evaluate the clinical curative effect objectively, and to provide a new thought for the improvement of the curative effect of the internal and external combination of the traditional Chinese medicine for improving the curative effect of the insomnia in the future; The curative effect of the traditional Chinese medicine foot bath and the warm water foot bath in the treatment of insomnia is observed and compared, and the curative effect of the traditional Chinese medicine foot bath is further evaluated and the action mechanism of the traditional Chinese medicine foot bath is further evaluated, so that the clinical basis for improving the curative effect of the insomnia is provided for the traditional Chinese medicine foot bath method. The method of the study was to select the patients with two-deficiency type of heart and spleen in the outpatient department of Dongzhimen Hospital of Beijing University of Traditional Chinese Medicine. The patients were randomly assigned to the oral decoction group (group A), and the oral decoction was combined with the warm water foot bath group (group B), and the oral decoction was used to match the traditional Chinese medicine foot bath group (group C). Group A is prepared by the following steps of: adding and adding the spleen and the decoction for oral administration, and taking the day and evening as an agent, and taking the decoction in the morning and the evening. The B group was given to the spleen and soup for oral administration, and the warm water foot bath was used for every night. Group C was taken as the basis of the addition and subtraction of the decoction of the spleen and the decoction, and the decoction dregs were added to the foot bath for once every night. The three-group treatment course was 28 days. After the course of treatment, three groups of TCM syndrome and the change of PSQI score were observed, and the clinical curative effect was determined. Study Results 1. On the basis of the baseline data, 60 cases were enrolled in the study, of which 20 cases were taken orally and 20 cases of the warm water foot bath group (group B) were matched with the oral decoction, and 20 cases were matched with the traditional Chinese medicine foot bath group (group C). The sex, age, course, height, body weight, degree of culture, occupational distribution, symptom score and PSQI score of the three groups were not statistically significant (P0.05). After the end of the treatment, the symptoms and total score of the three groups decreased and the difference was statistically significant (P0.05). Among them, there were significant differences in the three groups (P0.05). In group B, group B was superior to group A (P0.05), and group C was better than that of group A and B (P0.05). There was no significant difference between group A and group B in group A and group B (P <0.05), but group C was better than that in group A and B (P <0.05). in group B, group B was better than that of group A and group B in group A and B in group B, and in group B, group B was better than group A. The scores of PSQI and the total score of PSQI in three groups were decreased and the difference was statistically significant (P0.05). Among the three groups, the sleep quality, time of sleep and total score were significantly different (P0.05). In group B, group B was superior to group A (P0.05), and group C was superior to group A and group B (P0.05). In terms of total score, group C was superior to group A and group B (P0.05), and there was no significant difference between group A and group B (P0.05). The results showed that group C was better than that of group A and group B in the aspects of reducing PSQI score and falling asleep time and daytime dysfunction, while group B was significantly better than group A in time of sleep and daytime dysfunction. After the treatment, the total effective rate of group A was 80.00%, the total effective rate of group B was 85%, and the total effective rate of C group was 90%. and there was a significant difference (P0.05). The effect of group A and group B was similar to that of group B (P0.05). The curative effect of group C was better than that of group A and group B (P0.05). The results showed that group A and group B were better than group A and group B, and group A and group B were similar to those in group B. The total effective rate of group A was 80.00%, the total effective rate of group B was 85% and the total effective rate of C group was 95%. and there was a significant difference (P0.05). The effect of group A and group B was similar to that of group B (P0.05), and the curative effect of group C was better than that of group A and group B (P0.05). The clinical effect of group A and group B was similar to that of group A and group B. The result of the study is that the combined therapy of the external and external combination treatment of the spleen decoction is superior to that of the pure oral decoction and the warm water foot bath in the aspect of reducing the PSQI score of the patient and improving the clinical symptoms of the traditional Chinese medicine, The symptoms such as the fatigue force of God and the cold limbs cold and other symptoms and the time of falling asleep and the day dysfunction are superior to the pure oral decoction. In general, the combination therapy for both internal and external treatment of the spleen and the stomach has a good clinical curative effect, and is worthy of being popularized and applied at the grass-roots level.
【学位授予单位】:北京中医药大学
【学位级别】:硕士
【学位授予年份】:2017
【分类号】:R256.23
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