活血生肌方干预糖尿病足溃疡的作用及机制

发布时间：2018-12-09 13:11

【摘要】：目的:探讨活血生肌方干预糖尿病足溃疡的临床疗效。方法:将本院自2014年1月—2015年10月收集的糖尿病足溃疡患者60例,随机分为治疗组和对照组,两组在降血糖、扩血管、抗感染、外科常规换药的基础上,治疗组口服加外用活血生肌方,治疗90 d后观察两组溃疡创面面积、分泌物、肉芽生长、愈合率。结果:治疗90 d后:(1)两组患者的溃疡创面大小、分泌物、肉芽生长状况与治疗前比较:各项疗效指标都有明显改善,差异有统计学意义(P0.05),但治疗组的疗效指标的改善优于对照组,差异有统计学意义(P0.05)。(2)溃疡面积:治疗组0 cm2,对照组0.9 cm2,有差异(P0.05)。(3)溃疡面愈合率:治疗组愈合率为96.43%,对照组愈合率为74.07%,有显著差异(P0.01),具有统计学意义。结论:活血生肌方有显著化瘀止痛、消肿生肌,促进糖尿病足溃疡愈合的作用。
[Abstract]:Objective: to investigate the clinical effect of Huoxue Shengji recipe on diabetic foot ulcer. Methods: from January 2014 to October 2015, 60 patients with diabetic foot ulcer were randomly divided into treatment group and control group. After 90 days of treatment, the wound area, secretion, granulation growth and healing rate of the two groups were observed. Results: 90 days after treatment: (1) the ulcer wound size, secretion, granulation growth status of the two groups were significantly improved compared with before treatment, the difference was statistically significant (P0.05). But the improvement of curative effect index in the treatment group was better than that in the control group, the difference was statistically significant (P0.05). (2) ulcer area: 0 cm2, in the treatment group, 0.9 cm2, in the control group. The healing rate of ulcer surface was 96.43 in the treatment group and 74.07 in the control group (P0.05). (3). Conclusion: Huoxue Shengji prescription has the effect of removing stasis and relieving pain, eliminating swelling and generating muscle, and promoting the healing of diabetic foot ulcer.
【作者单位】：河南省黄河科技学院;河南省中医药研究院附属医院;
【基金】：河南省科技厅重点科技攻关项目(152102310170)
【分类号】：R259

【相似文献】