柴胡加龙骨牡蛎汤加减方治疗痰热内扰证失眠症的短期疗效观察

发布时间：2019-01-02 15:23

【摘要】：目的:观察柴胡加龙骨牡蛎汤加减方治疗痰热内扰型失眠症的短期疗效。方法:选择100例失眠痰热内扰证患者,随机分为治疗组(柴胡加龙骨牡蛎汤加减方)51例、对照组(唑吡坦)49例。两组均采用匹兹堡睡眠质量指数(PSQI)、中医证候总分评定疗效,疗程为2周。结果:治疗组的总有效率90.20%,优于对照组的81.63%(P0.05),其PSQI总分、中医证候总分在治疗1周后,2周后均明显低于对照组(P0.01),"寐而易醒""多梦""心烦""胸闷""口苦""头晕"6个症状积分低于对照组(P0.05);不良反应发生率差异无统计学意义,但治疗组起效时间晚于对照组(P0.01)。结论:柴胡加龙骨牡蛎汤加减方治疗痰热内扰型失眠症的短期疗效确切,不良反应少,值得推广。
[Abstract]:Objective: to observe the short-term curative effect of chaihu plus Longgu oyster decoction in treating phlegm-heat internal disturbance insomnia. Methods: 100 patients with internal disturbance of insomnia and phlegm heat were randomly divided into treatment group (51 cases) and control group (49 cases). The two groups were treated with Pittsburgh Sleep quality Index (PSQI),) for 2 weeks. Results: the total effective rate of the treatment group was 90.20%, which was better than that of the control group (81.63%, P0.05). The total score of PSQI and TCM syndromes in the treatment group was significantly lower than that in the control group after 1 week treatment and 2 weeks after treatment (P0.01). The scores of 6 symptoms of "sleep and easy waking", "more dreams", "upset", "chest tightness", "bitter mouth" and "dizziness" were lower than those in the control group (P0.05). There was no significant difference in the incidence of adverse reactions, but the effective time in the treatment group was later than that in the control group (P 0.01). Conclusion: the short-term curative effect of chaihu plus Longgu oyster decoction in treating phlegm-heat internal disturbance insomnia is definite, the adverse reaction is few, and it is worth popularizing.
【作者单位】：北京中医药大学东方医院康复科;北京中医药大学东方医院脑病二科;
【基金】：北京市科技计划课题(No.Z13110200680000) 北京中医药大学东方医院人才培养计划项目(东方新星)(No.DFRC2014C01)~~
【分类号】：R256.23

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