RPH-4联合消痔灵注射治疗中度直肠内脱垂的临床疗效观察

发布时间：2019-01-02 17:57

【摘要】：目的:观察RPH-4联合消痔灵注射治疗中度直肠内脱垂的临床疗效。材料与方法:选取2014年12月至2016年12月在辽宁省肛肠医院收入院的82例中度直肠内脱垂患者,随机分为治疗组和对照组,每组41例。治疗组采用RPH-4联合消痔灵注射的手术方式,对照组采用传统结扎的手术方式,观测症状、直肠内脱垂程度、术后疼痛、术后出血、手术时间、伤口愈合时间,判定疗效。采用SPSS17.0进行统计分析,计量资料均用均值±标准差(`x±s)表示,符合正态性分布即用t检验,非正态性分布即用非参数检验。计数资料用卡方检验。等级资料用秩和检验。P0.05时无差异,无统计学意义;P0.05时有差异,有统计学意义;P0.01时有显著性差异。结果:1.治疗组、对照组治疗后均能改善中度直肠内脱垂患者的症状,P0.05;治疗后治疗组改善症状情况优于对照组,P0.01。2.治疗后治疗组改善中度直肠内脱垂的脱垂程度优于对照组,P0.01。3.治疗组总有效率97.56%、治愈率24.39%,对照组总有效率95.12%、治愈率9.72%,治疗组临床疗效优于对照组,P0.01。4.治疗组术后疼痛较对照组明显减轻,P0.01;治疗组术后出血发生率较对照组低,P0.05;治疗组手术时间、伤口愈合时间明显较对照组缩短,P0.01。结论:1.RPH-4联合消痔灵注射与传统结扎手术均能改善中度直肠内脱垂患者症状,但RPH-4联合消痔灵注射对改善中度直肠内脱垂患者的症状优于传统结扎手术。2.RPH-4联合消痔灵注射对改善中度直肠内脱垂的脱垂程度优于传统结扎手术。3.RPH-4联合消痔灵注射治疗中度直肠内脱垂总有效率97.56%、治愈率24.39%,临床疗效优于对照组。4.RPH-4联合消痔灵注射与传统结扎手术相比,患者术后痛苦小、术后出血发生率低、手术时间短、术后伤口愈合快。
[Abstract]:Objective: to observe the clinical effect of RPH-4 combined with Xiaozhiling injection in the treatment of moderate rectal prolapse. Materials and methods: from December 2014 to December 2016, 82 patients with moderate rectal prolapse were randomly divided into treatment group (n = 41) and control group (n = 41). The treatment group was treated with RPH-4 combined with Xiaozhiling injection, the control group was treated with traditional ligation, the symptoms, the degree of rectal prolapse, postoperative pain, postoperative bleeding, operation time, wound healing time were observed and the curative effect was evaluated. The statistical analysis is carried out by SPSS17.0. The measured data are expressed as mean 卤standard deviation (`x 卤s). The normal distribution is measured by t test, and the non-normal distribution by nonparametric test. The counting data are checked by chi-square. Grade data with rank sum test. P0.05 when there was no difference, no statistical significance; P0.05 there was difference, there was statistical significance; P0.01 had significant difference. Results: 1. Treatment group, control group can improve the symptoms of patients with moderate rectal prolapse after treatment, P0.05, treatment group after treatment is better than the control group, P0.01.2. After treatment, the degree of moderate rectal prolapse in the treatment group was better than that in the control group (P 0.01.3). The total effective rate of the treatment group was 97.56 and the cure rate was 24.39. The total effective rate of the control group was 95.12 and the cure rate was 9.72. The clinical efficacy of the treatment group was better than that of the control group (P0.01.4). The incidence of postoperative bleeding in the treatment group was lower than that in the control group (P0.05). The operation time and wound healing time in the treatment group were significantly shorter than that in the control group (P0.01). Conclusion: 1.RPH-4 combined with Xiaozhiling injection and traditional ligation can improve the symptoms of patients with moderate rectal prolapse. However, RPH-4 combined with Xiaozhiling injection was superior to traditional ligation in improving the symptoms of patients with moderate rectal prolapse, and 2.RPH-4 combined with Xiaozhiling injection was superior to traditional ligation surgery in improving the degree of prolapse of moderate rectal prolapse. The total effective rate of 3.RPH-4 combined with Xiaozhiling injection in the treatment of moderate rectal prolapse was 97.56. The cure rate was 24.39 and the clinical curative effect was better than that in the control group. Compared with the traditional ligation operation, 4.RPH-4 combined with Xiaozhiling injection had less postoperative pain, lower incidence of postoperative bleeding, shorter operative time and faster wound healing.
【学位授予单位】：辽宁中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R266

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