108例成人斯蒂尔病患者中医证型研究

发布时间：2019-01-04 16:24

【摘要】：目的:探讨成人斯蒂尔病(AOSD)的中医证型分布与患者一般情况、服用糖皮质激素时间及C-反应蛋白(CRP)、血清铁蛋白(SF)的相关性。方法:回顾性纳入2011年1月至2015年12月住院确诊的AOSD患者108例,频数表描述证型分布,SPSS19.0统计分析各影响因素与证型相关性。结果:108例AOSD患者67.59%在春夏发病,出现频率大于50%的症状有发热、皮疹、咽痛、关节痛、肌痛、瘰疬肿痛、乏力,证型分布为气阴两虚兼湿热痹阻证(25.93%)、湿热痹阻证(21.30%)、阴虚内热证(17.59%)、气营两燔证(15.74%)、气阴两虚证(10.19%)、卫气同病证(9.26%);病程及服用激素时间长短、CRP、SF均影响证型分布。结论:AOSD多见中青年女性,典型症状为发热、皮疹、咽痛、关节痛,中医证型以虚实夹杂的复合证型气阴两虚兼湿热痹阻证最常见,卫气同病证最少见,病程、服用激素时间、CRP、SF与证型有明显相关性,即病程及服用激素时间越长表现为虚证越明显,CRP、SF越高病程越短则实证越明显。
[Abstract]:Objective: to investigate the relationship between the distribution of TCM syndromes of adult Steele disease (AOSD) and the general condition of patients, the time of taking glucocorticoid and the serum ferritin (SF) (SF) of C-reactive protein (CRP),). Methods: 108 AOSD patients who were hospitalized from January 2011 to December 2015 were retrospectively included. The distribution of syndromes was described by frequency table, and the correlation between the influencing factors and syndrome type was analyzed statistically by SPSS19.0. Results: 67.59% of the patients with AOSD developed in spring and summer. The symptoms with frequency greater than 50% were fever, rash, pharynx, arthralgia, myalgia, scrofula swelling and fatigue. The syndrome type was deficiency of qi and yin and dampness and heat obstruction (25.93%). Damp-heat obstruction syndrome (21.30%), Yin deficiency internal heat syndrome (17.59%), Qi Ying two burnt syndrome (15.74%), qi and yin deficiency syndrome (10.19%), Wei Qi syndromes (9.26%); Course of disease, duration of taking hormone and CRP,SF all affected the distribution of syndromes. Conclusion: the typical symptoms of AOSD are fever, rash, pharynx, arthralgia. The syndrome of deficiency and deficiency of qi and yin combined with damp-heat obstruction is the most common type of TCM syndrome, the disease of Wei Qi is the rarest, the course of disease, the time of taking hormone. There was a significant correlation between CRP,SF and syndromes, that is, the longer the course of disease and the time of taking hormone, the more obvious the deficiency syndrome, the shorter the course of CRP,SF, the more obvious the evidence was.
【作者单位】：中国中医科学院望京医院风湿病科;
【基金】：中国中医科学院名医名家传承项目(CM2014GD1011)-胡荫奇学术思想与临床经验传承研究
【分类号】：R259

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