搜风通络汤对PTED术后神经根症状恢复疗效分析

发布时间：2019-01-09 08:10

【摘要】：目的:分析搜风通络汤对腰椎间盘突出症经皮椎间孔镜技术(PTED)术后神经根症状恢复情况的影响,并与肌松药盐酸乙哌立松功效作比较。方法:选择腰椎间盘突出症PTED术后患者60例,随机分成基础组、实验组、对照组各20例,基础组予地塞米松5mg静滴qd抗炎止痛+20%甘露醇250m1静滴脱水治疗,实验组基础治疗+搜风通络汤口服,对照组基础治疗+盐酸乙哌立松50mg 口服tid,分别在术后3天、术后1周、术后4周三个时间点用腰椎JOA评分和视觉疼痛评分VAS评价三组治疗效果。结果:术后4周时三组JOA评分显效率分别为:基础组40%,治疗组85%,对照组75%;术后3天,三组JOA评分分别为:基础组17.40±1.88,治疗组18.70±2.25,对照组18.05±2.19,VAS评分分别为:基础组4.0(2.0),治疗组4.0(1.0),对照组3.5(1.0),三组之间JOA及VAS评分较术前明显改善,但此时组间没有明显差别(P0.05);术后1周,三组JOA评分分别为:基础组19.55±1.10,治疗组21.45±1.97,对照组20.85±2.52,VAS评分分别为:基础组3.0(1.0),治疗组2.0(1.0),对照组2.0(1.0),三组JOA评分和VAS评分较术后3天改善明显,治疗组和对照组疗效优于基础组;术后4周,三组JOA评分分别为:基础组19.80± 1.54,治疗组25.15±2.03,对照组23.85±2.25,VAS评分分别为:基础组1.0(1.0),治疗组0.5(1.0),对照组1.0(0.0),三组临床疗效较术后1周有所改善,治疗组和对照组优于基础组,且治疗组优于对照组。结论:搜风通络汤对腰椎间盘突出症PTED术后遗留神经根症状有持续改善效果,并且临床疗效优于盐酸乙哌立松。
[Abstract]:Objective: to analyze the effect of Soufeng Tongluo decoction on the recovery of nerve root symptoms after percutaneous intervertebral foramen technique (PTED) in lumbar disc herniation and compare with the effect of muscle relaxant Epiperidone hydrochloride. Methods: sixty patients with lumbar disc herniation after PTED were randomly divided into basic group (n = 20), experimental group (n = 20) and control group (n = 20). The basic group was treated with dexamethasone 5mg intravenous drip of qd for anti-inflammatory and analgesic 20% mannitol 250m1 dehydration. The experimental group was treated by oral administration of Soufeng Tongluo decoction, while the control group was treated with 50mg on 3 days and 1 week after operation, respectively. The three groups were evaluated with lumbar JOA score and visual pain score (VAS) at 4 weeks after operation. Results: at 4 weeks after operation, the effective rates of JOA scores in the three groups were as follows: 40 in the basic group, 85 in the treatment group and 75 in the control group; 3 days after operation, the JOA scores of the three groups were 17.40 卤1.88 in the basic group, 18.70 卤2.25 in the treatment group, and 18.05 卤2.19 in the control group, respectively: 4.0 (2.0) in the basic group and 4.0 (1.0) in the treatment group. In the control group (3.5 (1.0), the scores of JOA and VAS in the three groups were significantly improved compared with those before operation, but there was no significant difference between the three groups at this time (P0.05). 1 week after operation, the JOA scores of the three groups were 19.55 卤1.10 in the basic group, 21.45 卤1.97 in the treatment group and 20.85 卤2.52 in the control group, respectively. In the control group (2.0), the JOA score and VAS score of the three groups were significantly improved compared with the 3 days after operation. The curative effect of the treatment group and the control group was better than that of the basic group. 4 weeks after operation, the JOA scores of the three groups were 19.80 卤1.54 in the basic group, 25.15 卤2.03 in the treatment group and 23.85 卤2.25 in the control group, respectively. In control group 1.0 (0.0), the clinical efficacy of the three groups was improved 1 week after operation, the treatment group and the control group were superior to the basic group, and the treatment group was better than the control group. Conclusion: Soufeng Tongluo decoction can improve the nerve root symptom of lumbar intervertebral disc herniation after PTED, and the clinical effect is better than Epipraxone hydrochloride.
【学位授予单位】：南京中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R274.9

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