滋肾增水汤联合针刺治疗月经过少的临床研究

发布时间：2019-01-09 16:36

【摘要】：目的:观察滋肾增水汤联合针刺治疗月经过少的临床疗效并初步探讨其机理。方法:根据入选及排除标准随机选取2015年1月~2015年12月就诊于广西中医药大学第一附属医院妇科门诊或住院部的肾阴虚型月经过少患者60例。按随机数字表法分治疗组及对照组两组,各组分别纳入30名。治疗组患者予口服中药方并联合针刺治疗,对照组口服西药补佳乐联合黄体酮序贯治疗,3个月经周期后观察两组患者月经量的恢复、中医症候的改善情况及对子宫内膜的影响,通过统计学方法处理。结果:治疗前通过对两组患者临床症状评分、月经量、子宫内膜厚度比较,两组差异无统计学意义(P0.05),具有可比性。经治疗3个月经周期后,两组患者各项观察指标均较疗前有所改善。其中治疗组月经情况特别是月经色、质、量的改善以及伴随中医症候的改善明显优于对照组,疗效具有统计学差异(P0.05)。两组患者治疗3个月经周期后月经晚期(月经周期第21~24天)子宫内膜厚度均增加,但组间比较无统计学差异(P0.05)。本研究治疗组30例患者的月经量疗效好转2例,显效9例,治愈17例,总有效率为93.32%,对照组为好转7例,显效5例,治愈10例,总有效率为73.32%,治疗组优于对照组。治疗组与对照组的中医症候总疗效均有改善,治疗组中医临床症状总有效率为90%,对照组为66.66%,并且治疗组中医临床各症状改善率明显优于对照组,差异具有统计学差异(P0.05)。治疗期间,两组均未发生无不良反应及并发症。结论:滋肾增水汤联合针刺治疗肾阴虚型月经过少临床疗效确切,可明显增加患者的月经量并且改善伴随中医临床症候,疗效优于雌孕激素序贯治疗,且用药安全,无明显不良反应。
[Abstract]:Objective: to observe the clinical effect of Zishen Zengshui decoction combined with acupuncture on menorrhagia and explore its mechanism. Methods: according to the criteria of inclusion and exclusion, 60 patients with menorrhagia due to deficiency of kidney yin were randomly selected from January 2015 to December 2015 in gynecological outpatient or inpatient department of the first affiliated Hospital of Guangxi University of traditional Chinese Medicine. According to the random digital table method, the treatment group and the control group were divided into two groups. The patients in the treatment group were treated with traditional Chinese medicine combined with acupuncture, while the patients in the control group were treated with western medicine Bujialue combined with progesterone. The menstrual volume of the two groups was observed after three menstrual cycles. The improvement of TCM symptoms and its influence on endometrium are dealt with by statistical method. Results: there was no significant difference between the two groups in clinical symptom score, menstrual volume and endometrial thickness before treatment (P0.05). After 3 menstrual cycles, the observation indexes of the two groups were improved. The treatment group especially menstrual color, quality, quantity improvement and accompanied with the improvement of TCM symptoms were significantly better than the control group, the curative effect was statistically different (P0.05). The endometrial thickness of the two groups increased after 3 menstrual cycles (21 ~ 24 days of menstrual cycle), but there was no significant difference between the two groups (P0.05). In the study group, there were 2 cases of menorrhagia improvement, 9 cases of remarkable effect, 17 cases of cure and 93.32% of total effective rate, while 7 cases of improvement, 5 cases of remarkable effect, 10 cases of cure, and 73.32% of total effective rate in the control group. The treatment group was superior to the control group. The total curative effect of TCM symptoms in the treatment group and the control group were improved. The total effective rate of TCM clinical symptoms in the treatment group was 90 and that in the control group was 66.66.The improvement rate of the TCM symptoms in the treatment group was obviously better than that in the control group. The difference was statistically significant (P0.05). During the treatment, no adverse reactions and complications occurred in both groups. Conclusion: Zishen Zengshui decoction combined with acupuncture is effective in the treatment of excessive menstruation of kidney yin deficiency type. It can obviously increase the menstrual volume of the patients and improve the clinical symptoms of TCM. The curative effect is superior to the sequential treatment of estrogen and progesterone, and the medication is safe. There was no obvious adverse reaction.
【学位授予单位】：广西中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R271.11

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