加味炙甘草汤治疗气阴两虚型稳定型心绞痛临床观察

发布时间：2019-01-18 19:12

【摘要】：目的:观察加味炙甘草汤治疗气阴两虚型稳定型心绞痛的临床疗效。方法:搜集30位符合标准的气阴两虚型稳定型心绞痛门诊患者,给予炙甘草汤治疗,并依据临床症状,辩证进行适当加味。每天一付汤药,早饭前、晚饭后半小时温服,连续服用6周。观察治疗前和治疗后的临床症状积分变化,硝酸甘油减停率及缺血性心电图变化,同时应用SPSS19.0进行统计学分析、处理。结果:1.中医症状总积分比较:治疗前总积分为15.57 ± 3.69,治疗后总积分为 7.67±3.37,平均降低 7.90 ± 0.32,P 值0.05。2.中医症状单项积分比较:治疗前后主症各项单项积分P值均0.01,治疗前后次症各项单项积分中面色晦滞,神疲懒言P值0.05,其余次症单项积分P值均0.05。3.硝酸甘油减停率疗效比较:停药患者6名(20.00%),减量患者13名(43.33%),不变患者5名(16.67%),总减停率为63.33%。4.心电图疗效比较:显效患者4名(13.33%),有效患者14名(46.67%),无效患者12名(40.00%),总有效率为60.00%。5.总有效率:30位患者的疗效包括显效8名(26.67%),有效17名(56.67%),无效 5 位(16.66%),总有效率 83.33%。结论:1.本论文所采用的加味炙甘草汤方剂对于气阴两虚型稳定型心绞痛患者,可降低其中医症候积分,降低其硝酸甘油减停率,改善其临床症状。2.加味炙甘草汤方剂可以改善气阴两虚型稳定型心绞痛患者的缺血性心电图。
[Abstract]:Objective: to observe the clinical effect of modified Zhigancao decoction on stable angina pectoris with deficiency of Qi and Yin. Methods: thirty outpatients with stable angina pectoris of Qi and Yin deficiency type were collected and treated with Zhigancao decoction. A daily soup medicine, before breakfast, half an hour after supper, take 6 weeks. The changes of clinical symptom score, nitroglycerin reduction rate and ischemic electrocardiogram were observed before and after treatment. SPSS19.0 was used for statistical analysis and treatment. Results: 1. Comparison of the total score of TCM symptom: the total integral before treatment was 15.57 卤3.69, the total score after treatment was 7.67 卤3.37, the average decrease was 7.90 卤0.32 (P = 0.05.2). Comparison of the single score of TCM symptom: P value of each item integral of main symptom before and after treatment was 0.01, in every single integral of secondary symptom before and after treatment, the face was dull, the P value was 0.05, and the other symptoms were all 0.05.3. Comparison of the therapeutic effects of nitroglycerin: 6 patients (20.00%), 13 patients (43.33%), 5 patients (16.67%), 63.33.4. Electrocardiogram (ECG) efficacy was compared in 4 patients (13.33%), 14 patients (46.67%) and 12 patients (40.00%). The total effective rate was 60.00.5. The total effective rate of 30 patients included 8 patients (26.67%), 17 patients (56.67%), 5 ineffective patients (16.66%). The total effective rate was 83.33%. Conclusion: 1. In this paper, the prescription of modified Gancao decoction for stable angina pectoris with deficiency of both qi and yin can reduce the integral of TCM symptoms, reduce the stopping rate of nitroglycerin, and improve its clinical symptoms. 2. Modified Zhigancao decoction can improve the ischemic electrocardiogram of stable angina pectoris with deficiency of Qi and Yin.
【学位授予单位】：黑龙江中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R259

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