冠心病慢性心力衰竭合并高血压患者证候要素和证候分布特点

发布时间：2019-01-22 17:11

【摘要】：目的比较合并高血压对冠心病慢性心力衰竭患者证候要素及应证组合是否产生影响,为冠心病慢性心力衰竭患者的辨证分型提供一定参考。方法通过多中心横断面研究,收集和分析14家临床协作单位252例冠心病慢性心力衰竭患者,根据是否合并高血压,将患者分为冠心病慢性心力衰竭合并高血压组和冠心病慢性心力衰竭不合并高血压组,比较2组患者的性别、年龄、心力衰竭类型、心功能等级、病性类证候要素、病位类证候要素及应证组合分布规律,完成统计分析并探讨其规律。结果 2组患者性别、年龄和心功能比较无差异;2组患者中出现频次最高的病性类证候要素均为气虚、血瘀、阴虚,但合并高血压组患者中气虚的出现频率低于不合并高血压组(P0.01);2组患者的主要病位类证候要素均为心,同时涉及到脾、肺、肾、肝,且2组间无显著差异(P0.05);2组患者的应证组合均以多个证候要素组合最为多见,但合并高血压组两证组合多于不合并高血压组(P0.05);气虚血瘀和气阴两虚兼血瘀是冠心病慢性心力衰竭合并高血压组最常见的证候类型。结论冠心病慢性心力衰竭患者合并高血压时,其病性证候要素中气虚比例减少,其应证组合中,多以两证组合为主,且气虚血瘀和气阴两虚兼血瘀是最常见的证候类型。
[Abstract]:Objective to compare the effects of hypertension on syndromes and syndromes in patients with coronary heart failure (CHD), and to provide reference for syndrome differentiation and classification of patients with CHF. Methods based on the multi-center cross-sectional study, 252 patients with chronic heart failure of coronary heart disease in 14 clinical collaborating units were collected and analyzed according to whether they were complicated with hypertension. The patients were divided into two groups: coronary heart disease with chronic heart failure combined with hypertension and coronary heart failure without hypertension. The sex, age, type of heart failure, cardiac function grade, factors of disease syndromes were compared between the two groups. The distribution of syndromes and syndromes were analyzed statistically and discussed. Results there was no difference in sex, age and cardiac function between the two groups. In the two groups, the most frequent symptoms were qi deficiency, blood stasis and yin deficiency, but the frequency of qi deficiency in patients with hypertension was lower than that in patients without hypertension (P0.01). The main syndromes of the two groups were heart, involving spleen, lung, kidney and liver, and there was no significant difference between the two groups (P0.05). The combination of multiple syndromes was the most common in the two groups, but the combination of two syndromes in the combined hypertension group was more than that in the non-hypertension group (P0.05). Qi deficiency and blood stasis and deficiency of qi and yin combined with blood stasis are the most common syndromes in patients with coronary heart disease and chronic heart failure combined with hypertension. Conclusion when coronary heart disease patients with chronic heart failure are complicated with hypertension, the proportion of qi deficiency in the essential factors of disease syndromes is decreased. The most common syndromes are qi deficiency and blood stasis and qi deficiency and yin deficiency combined with blood stasis.
【作者单位】：北京中医药大学中医学院;首都医科大学中医药学院;湖北省武汉市中医院心内科;
【基金】：国家中医药管理局中医药行业科研专项资助项目(No.200807007) 教育部新世纪优秀人才支持计划(No.NCET-13-0692) 北京中医药大学杰出青年人才项目(No.2015-JYB-XYQ002);北京中医药大学创新团队(No.2011-CXTD-06) 国家自然科学基金资助项目(No.81470191,No.81503400)~~
【分类号】：R259

【相似文献】