关节穴位贴治疗筋脉瘀滞型骨性关节炎的随机对照研究

发布时间：2019-02-17 15:08

【摘要】：目的评价关节穴位贴治疗筋脉瘀滞型骨性关节炎的临床疗效及安全性。方法 108例筋脉瘀滞型骨性关节炎患者随机分为穴位关节贴组、天和骨通贴膏组、安慰剂敷贴组各36例。各组均予相应穴位敷贴治疗,敷贴时间为(12±2)h,各组均连续用药4周。比较患者治疗前后不同时间视觉模拟疼痛评分(VAS)、局部疼痛压力计分、中医证候评分、疼痛缓解起效时间及不良反应情况,并评价疼痛疗效。结果关节穴位贴组疼痛疗效总有效率为94.44%,优于天和骨通贴膏组74.29%和安慰剂组25.00%(P0.01)。各组治疗1、2、3、4周VAS评分、中医证候评分均较治疗前明显降低(P0.05);治疗3周关节穴位贴组、天和骨痛贴膏组VAS评分均明显低于安慰剂组(P0.05);治疗4周关节穴位贴组VAS评分最低(P0.05);治疗3、4周时关节穴位贴组、天和骨痛贴膏组中医证候评分均较安慰剂组明显降低(P0.05)。治疗后关节穴位贴组、天和骨痛贴膏组局部疼痛压力计分分别与安慰剂比较,差异均具有统计学意义(P0.05)。关节穴位贴组疼痛缓解时间最短(P0.05)。结论关节穴位贴治疗筋脉瘀滞型骨关节炎疗效确切,能缓解疼痛,起效快,安全性好。
[Abstract]:Objective to evaluate the clinical efficacy and safety of joint acupoint plaster in the treatment of osteoarthritis with stagnation of veins and veins. Methods 108 cases of osteoarthritis with blood stasis were randomly divided into three groups: acupoint joint sticking group, Tianhe Gutong plaster group and placebo application group. Each group was treated with corresponding acupoint application for (12 卤2) h, and each group was treated continuously for 4 weeks. The scores of (VAS), local pain pressure gauge, TCM syndrome score, onset time of pain relief and adverse reactions were compared before and after treatment, and the curative effect of pain was evaluated. Results the total effective rate of joint acupoint application group was 94.444.29%, which was better than that of Tianhe Gutong plaster group (74.29%) and placebo group (25.00%) (P0.01). The scores of VAS and TCM syndromes were significantly lower in each group than those before treatment (P0.05), the VAS scores of Tianhe Gutong paste group and Tianhe Gutong plaster group were significantly lower than those of placebo group after 3 weeks of treatment (P0.05), and that of Tianhe Gutong plaster group was significantly lower than that of placebo group (P0.05). After 4 weeks of treatment, the VAS score of the joint acupoint patch group was the lowest (P0.05), and the TCM syndrome score of the joint acupoint paste group and Tianhe Gutong paste group were significantly lower than that of the placebo group (P0.05). After treatment, there were significant differences in the scores of local pain pressure gauges and placebo between the joint acupoint sticking group and Tianhe Gutong paste group (P0.05). The time of pain relief was the shortest in the joint acupoint sticking group (P0.05). Conclusion the treatment of osteoarthritis by joint acupoint plaster is effective, effective and safe.
【作者单位】：天津中医药大学第一附属医院;
【基金】：国家自然科学基金(81673994) 天津市中医传承工作室
【分类号】：R246.9

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