针药结合对血虚风燥型特应性皮炎生活质量影响分析

发布时间：2019-03-08 16:30

【摘要】：目的：.研究遵循随机对照的原则,观察针刺联合中药治疗血虚风燥型特应性皮炎的临床研究,评价该疗法的临床疗效和对患者生活质量的影响,推广一项有明确疗效的,能造福于患者的疗法——针刺疗法。方法：对纳入研究的66例血虚风燥型特应性皮炎的病例随机分为两组,分别是：针刺联合中药组(治疗组)和单纯中药组(对照组)。4周为1个疗程,共治疗3个疗程。于治疗前、治疗4周后、治疗8周后、治疗12周后和随访4周五个观察点分别观察并记录患者的SCORAD评分、特应性皮炎症状量、生活质量指数等数据,结果将根据疗效标准,分析统计患者的评分情况,从而得出结论。结果：1 SCORAD评分两组患者在治疗后各观察时点SCORAD均有下降趋向,在疗后4周时点两组之间对比差异没有统计学意义(P=0.4090.05,),但在疗后8周、12周及随访4周时其余各时点两组之间对比,差别均有统计学意义(P=0.045、0.001、0.0000.05),；提示在疗后8周、12周及随访4周里治疗组疗效较对照组好。表明针药结合明显改善血虚风燥型AD特应性皮炎皮肤情况、而且在缓解瘙痒程度方面均较对照组有疗效,并且结果显示针药结合能帮助改善睡眠质量。2 特应性皮炎症状量表两组结果提示治疗后各观察时点均有下降趋向,在疗后4周时点两组之间对比差别没有统计学意义(P=0.5370.05),,但在疗后8周、12周及随访4周时的其余各时点进行两组之间比较,差别均有统计学意义(P=0.045、0.003、0.0480.05)；提示在疗后8周、12周及随访4周里治疗组对AD患者症状改善疗效较对照组好且明显。说明,针药治疗不但具有很好的近期疗效,起效较快,而且具有更好的远期疗效,同时,针药结合更全面的缓解患者的症状。3生活质量量表两组结果提示治疗前及治疗后4周、8周、12周两组生活质量比较,在疗后12周及随访4周治疗组评分下降幅度较大,两组比较,差异有统计学意义(P=0.001、0.0140.05)。而其中感觉/症状(P0.05)、日常活动(P0.05)、休闲(P0.05)、工作/学习/假期(P0.05)、人际关系(P0.05)治疗影响(P0.05)这六个方面,其中人际关系及治疗影响这两方面无统计学意义外(P＞0.05),其余四方面在治疗前后均有差异,均有统计学意义(P0.05)。说明针药结合能更好地提高患者的生活质量。4 SCORAD评分、特应性皮炎症状量表及生活质量之间的相关性将两组三个量表进行分析后发现,三者之前具存在正相关(0r《+1,P0.05),,其中AD患者症状与生活质量相关程度较高(相关系数0.5＜r＜0.8,)；而症状与SCORAD程中度相关(相关系数0.5r0.8,)：生活质量评分与SCORAD相关程度较低(相关系数r0.5)。。由于患者长期受皮损等症状的影响,对于患者的生活质量来说肯定是有影响的,且随着皮损及症状严重程度加重,生活质量下降。结论：1 针刺联合中药治疗对血虚风燥型AD患者的临床疗效及临床显效水平较中药组高,且起效较快。2 针刺联合中药可以显著的改善AD患者皮肤皮损情况、而且在改善瘙痒等皮肤症状、方面均优于对照组、同时能有效地缓解由于疾病导致的各种症状,并提高生活质量。
[Abstract]:Purpose:. The clinical curative effect and the effect on the quality of life of the patients were evaluated according to the principle of randomized control, and the effect of the treatment on the quality of life of the patients was evaluated. Methods:66 cases of dry type atopic dermatitis, which were included in the study, were randomly divided into two groups: acupuncture combined with traditional Chinese medicine group (treatment group) and simple traditional Chinese medicine group (control group). Before and after treatment for 4 weeks, the SCORAD score of the patient, the symptom of atopic dermatitis, and the quality index of life were recorded and recorded for 8 weeks after the treatment for 4 weeks. The results will be based on the efficacy criteria, and the scores of the patients will be analyzed. So as to draw a conclusion. Results: There was no significant difference (P = 0.4090.05, P = 0.4090.05, P = 0.4090.05, P = 0.4090.05) between the two groups at 4 weeks after the treatment, but between the two groups at 8 weeks,12 weeks and 4 weeks after the treatment, there was no significant difference between the two groups (P = 0.4090.05). The difference was statistically significant (P = 0.045, 0.001, 0.0005), and the curative effect of the treatment group was better in the treatment group at 8 weeks,12 weeks and follow-up 4 weeks after the treatment. It is shown that the combination of the acupuncture and the medicine obviously improves the skin condition of the blood-deficiency wind-dry type AD atopic dermatitis, and has the curative effect on the control group in the aspect of relieving the itching degree of the blood, The results showed that the binding energy of the acupuncture was helpful to improve the sleep quality. The two groups of the symptoms of the symptoms of the atopic dermatitis showed a tendency to decrease in the observation time, and the contrast between the two groups was not statistically significant at the 4-week point after the treatment (P = 0.537.05). However, compared between the two groups at 8,12 and 4 weeks after the treatment, the difference was statistically significant (P = 0.045, 0.003, 0.0480.05), and the improvement of the symptoms of AD in the treatment group at 8,12 and 4 weeks after the treatment was better than that of the control group. The results of the two groups showed that the quality of life in the two groups before and after treatment,8 and 12 weeks before and after treatment. There was a significant difference in the score of the treatment group at 12 weeks after the treatment and the 4-week follow-up, and the difference was statistically significant (P = 0.001, 0.0140.05). There were no significant differences between the two aspects, such as the feeling/ symptom (P0.05), the day-to-day activity (P0.05), the leisure (P0.05), the work/ study/ leave (P0.05), the interpersonal relationship (P0.05), and the relationship between the two aspects (P> 0.05). The remaining four aspects were different before and after treatment (P0.05). It was found that the binding energy of the needle was better to improve the quality of life of the patients. The correlation between the SCORD score, the symptom scale of the atopic dermatitis and the quality of life of the two groups showed that there was positive correlation between the two groups (0r <+ 1, P0.05). There was a high correlation between the symptoms of AD and the quality of life (the correlation coefficient was 0.5 【学位授予单位】：广州中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R246.7

【相似文献】