水调散联合克痹骨泰片治疗湿热蕴结型痛风性关节炎的临床疗效观察

发布时间：2019-03-14 20:14

【摘要】：目的:观察水调散联合克痹骨泰片治疗痛风性关节炎急性发作期的治疗效果。通过治疗前后的血尿酸及症状体征评分的差异,探究水调散及克痹骨泰片在痛风性关节炎急性发作期治疗中的机理。材料与方法:通过辽宁中医药大学附属医院慢病二科门诊收集32例湿热蕴结型痛风性关节炎急性发作期的患者,予水调散联合克痹骨泰片治疗,以7天为一个观察周期,观察并记录其治疗前后血尿酸指标并对其治疗前后的症状体征进行评分。结果:1.经治疗后,总有效率为93.75%。说明本方案对痛风性关节炎急性发作期患者的病情有效。2.患者症状体征评分较治疗前有显著差异(P0.05),具有统计学意义。可见,本方案在对于急性期的治疗有效果,可以减轻患者痛苦。其中,对于红肿情况的改善效果最为明显。3.患者在治疗前后SUA水平比较无明显差异(P0.05),无统计学意义。故水调散联合克痹骨泰片的治疗方案降血尿酸效果不佳。结论:水调散联合克痹骨泰片对于湿热蕴结型痛风性关节炎急性发作期的治疗方案在缓解急性痛风性关节炎的临床症状及体征方面效果显著,可以帮助患者有效缓解急性期病情,为接下来的缓解期降尿酸治疗打好基础。且本治疗方案相比西药治疗副作用少,推荐临床使用。
[Abstract]:Objective: to observe the therapeutic effect of Shuixiao Powder combined with Kebi Gutai tablet on acute onset of gouty arthritis. According to the difference of serum uric acid and symptom and sign score before and after treatment, the mechanism of ShuijiaoSan and Kebi Gutai tablets in the treatment of gouty arthritis in acute attack stage was explored. Materials and methods: 32 patients with acute gouty arthritis of damp-heat accumulation type were collected from the second Department of chronic Diseases, affiliated Hospital of Liaoning University of traditional Chinese Medicine, and treated with Shuixiao Powder combined with Kepi Gutai tablet for 7 days as an observation period. The indexes of uric acid before and after treatment were observed and recorded, and the symptoms and signs before and after treatment were evaluated. Results: 1. After treatment, the total effective rate was 93.75%. It is indicated that this scheme is effective in the treatment of acute gouty arthritis patients. 2. The scores of symptoms and signs of the patients were significantly different from those before treatment (P0.05), with statistical significance. Visible, this program in the acute phase of the treatment has an effect, can alleviate the pain of the patient. Among them, the improvement effect of redness is the most obvious. 3. There was no significant difference in SUA level before and after treatment (P0.05), there was no statistical significance. Therefore, the treatment scheme of water dispelling powder combined with Kebi Gutai tablet is not effective in lowering blood uric acid. Conclusion: the combination of Shuixiao Powder and Kebi Gutai tablet is effective in relieving the clinical symptoms and signs of acute gouty arthritis in the acute stage of onset of gouty arthritis caused by damp-heat accumulation, and the therapeutic regimen is effective in relieving the clinical symptoms and signs of acute gouty arthritis. It can help the patients to relieve the acute phase effectively, and lay a good foundation for the treatment of uric acid reduction in the subsequent remission period. Compared with western medicine, this treatment scheme has fewer side effects, and it is recommended for clinical use.
【学位授予单位】：辽宁中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R259

【相似文献】