从湿辨证论治糖尿病干眼症的临床研究

发布时间：2019-04-02 06:01

【摘要】：目的:探索从湿辨证论治糖尿病性干眼症的中医理论及其治疗原则,通过观察祛湿化浊、理气运脾法治疗湿浊中阻、气机不畅型糖尿病干眼症的临床效果,并通过临床案例分析,丰富中医对本病的认识,丰富中医治疗糖尿病干眼症的治疗方法和及治疗原则。方法:将收集到的糖尿病合并干眼症患者病例随机分为两组,治疗组30例,对照组30例。治疗组采用祛湿化浊、理气运脾法联合爱丽滴眼液治疗,对照组仅用爱丽滴眼液治疗,两组均以1个月为一个疗程,治疗两个疗程后观察治疗前以及治疗后患者双眼的主观症状(眼干涩、眼红、眼痒、异物感、视物疲劳、眼疼痛),以及眼部体征(泪液分泌量、泪膜破裂的时间、角膜染色的情况、角膜知觉),并进行疗效评估。结果:显示治疗组显效11例,有效15例,进步4例,无效0例;对照组显效0例,有效3例,进步27例,无效0例。治疗组各项观察指标都有明显改善,差异具有统计学意义(P0.05);对照组患者中眼红、眼痒、Schirmer I Test无统计学意义(P0.05),其它症状及体征差异均有统计学意义(P0.05)。应用祛湿化浊、理气运脾法可改善糖尿病干眼症湿浊中阻型患者的主观症状,增加泪液分泌量,还可以改善角膜情况。结论:祛湿化浊、理气运脾法可以明显改善糖尿病干眼症患者症状,疗效明显。从湿论治糖尿病干眼症可以为此病的中医诊治提供新方法,新思路。
[Abstract]:Objective: to explore the theory of traditional Chinese medicine (TCM) and its principle of treating diabetic xerophthalmia from the view of dampness differentiation and syndrome differentiation, and to observe the clinical effect of removing dampness and removing turbidity and regulating qi and regulating spleen in treating diabetic dry eye disease of type of dampness and stagnation of qi. Through the analysis of clinical cases, enrich the understanding of TCM to this disease, enrich the traditional Chinese medicine treatment of diabetes mellitus dry eye treatment methods and treatment principles. Methods: the patients with diabetes mellitus complicated with dry eye were randomly divided into two groups: treatment group (n = 30) and control group (n = 30). The treatment group was treated with removing dampness and removing turbidity, regulating qi and regulating spleen combined with Allie eye drops, while the control group was treated only with Ally eye drops, and both groups were treated with one month as a course of treatment. After two courses of treatment, the subjective symptoms of both eyes (dry eyes, red eyes, itchy eyes, foreign matter sensation, visual fatigue, eye pain), as well as eye signs (the amount of lacrimal secretion, the time of tear film rupture), were observed before and after treatment. Corneal staining, corneal perception) and evaluation of the efficacy. Results: there were 11 cases in the treatment group, 15 cases in the effective group, 4 cases in the improvement, 0 cases in the control group, 0 cases in the control group, 3 cases in the control group, 27 cases in the improvement and 0 cases in the control group. The observation indexes of the treatment group were obviously improved, the difference was statistically significant (P0.05). Control group patients with red eyes, itching, Schirmer I Test had no statistical significance (P0.05), other symptoms and signs were statistically significant differences (P0.05). The method of removing dampness and removing turbidity and regulating qi and regulating spleen can improve the subjective symptoms, increase the amount of tear secretion, and improve the corneal condition in patients with diabetic dry eye disease with dampness and turbidity. Conclusion: the method of removing dampness and removing turbidity and regulating qi and regulating spleen can obviously improve the symptoms of diabetic dry eye patients, and the curative effect is obvious. The treatment of diabetes dry eye from the view of dampness can provide new methods and new ideas for the diagnosis and treatment of this disease.
【学位授予单位】：山东中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R259;R276.7

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