清化泄浊汤治疗慢性肾衰竭（湿热中阻证）的临床观察

发布时间：2019-04-16 17:10

【摘要】：目的:运用自拟方清化泄浊汤治疗慢性肾衰竭湿热中阻证患者,通过比较血肌酐、尿素氮下降水平、血红蛋白等实验室检查以及改善中医症状情况来验证清化泄浊汤的临床疗效及安全性。方法:将符合纳入标准的72例患者采用随机分组法(按1:1比例)分两组,两组均等例数,治疗组在基础对症治疗加服清化泄浊汤治疗,对照组在同样对症治疗基础上口服海昆肾喜胶囊治疗,8周为一疗程,观察一个疗程。观察两组病人治疗后血肌酐下降水平及改善中医临床症状体征情况的变化。结果:治疗后,两组临床总体疗效对比:治疗组36例中,显效5例,有效15例,稳定10例,无效6例,总有效率83.33%。对照组36例中,显效为5例,有效为11例,稳定12例,无效8例,总有效率77.77%。两组改善中医临床症状比较:治疗组显效例数为6例,有效例数为14例,稳定例数为11例,无效例数为5例,总有效率可达到86.11%;对照组显效9例,有效10例,稳定10例,无效7例,总有效率80.5%。结论:清化泄浊汤治疗慢性肾衰竭湿热中阻证有较好的临床疗效。在改善慢性肾衰竭湿热中阻证患者的中医症状、降低肌酐水平、延缓肾功能进展等方面有良好的作用。
[Abstract]:Objective: To study the clinical efficacy and safety of clearing away the turbid liquid by comparing the clinical symptoms of the patients with chronic renal failure and damp-heat with the self-prepared clear-away decoction for the treatment of chronic renal failure. Methods:72 patients who met the criteria of inclusion were divided into two groups according to the random grouping method (1:1 ratio). The number of the two groups was equal to that of the two groups. The treatment group was treated with a clear and clear decoction on the basis of symptomatic treatment, and the control group was treated by oral administration of the Shenxi capsule on the basis of the same symptomatic treatment, and the 8-week treatment course was a course of treatment. A course of treatment was observed. To observe the level of the reduction of the level of the blood and the sign of the clinical symptoms of the traditional Chinese medicine in the two groups. Results: The total effective rate was 83.33% in the treatment group,5 in the treatment group,15 in the effective,10 in the stable,6 in the treatment group and 83.33% in the total effective rate. In the control group,5 cases were effective,11 cases were effective,12 cases were stable,8 cases were ineffective, and the total effective rate was 77.77%. The two groups improved the clinical symptoms of the traditional Chinese medicine: the effective number of the treatment group is 6, the effective number is 14, the number of the stabilization is 11, the number of the invalid is 5, the total effective rate can reach 86.11%, the control group has the effect of 9 cases, the effective 10 cases, the stable 10 cases, the invalid 7 cases, the total effective rate is 80.5%. Conclusion: The treatment of damp-heat of chronic renal failure has good clinical curative effect in the treatment of chronic renal failure. Has good effect in improving the symptoms of the traditional Chinese medicine, reducing the level of the muscle and delaying the progression of the renal function, and the like in the damp-heat of the chronic renal failure.
【学位授予单位】：长春中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R277.5

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