养心通脉膏干预胸痹心痛的临床疗效观察
发布时间：2019-04-24 15:22
【摘要】：目的:探讨养心通脉膏以“益气和血、调补阴阳”法治疗胸痹心痛(稳定型心绞痛)的临床疗效,并分析其临床应用的作用机制。方法:病例均来源于2015年1月-2016年1月期间辽宁中医药大学附属第二医院心一科门诊患者,通过对44例符合纳入标准的胸痹心痛(稳定型心绞痛)患者进行前瞻性观察,对其流行病学资料、用药前后的中医症状积分的变化、西雅图心绞痛量表等进行统计分析,来评估养心通脉膏以“益气和血、调补阴阳”法治疗胸痹心痛(稳定型心绞痛)的临床疗效,并探讨胸痹心痛(稳定型心绞痛)的发病特点及机制。统计方法应用SPSS19.0统计软件,计数资料采用X2检验,计量资料采用T检验,等级资料采用秩和检验。结果:1养心通脉膏服用4周后,44例胸痹心痛(稳定型心绞痛)患者的中医症状均有所改善,其中胸闷、痛,心悸气短,倦怠乏力,畏寒肢冷,自汗及心烦、不寐多梦等症状改善较明显,差异有统计学意义(P0.05);而腰膝酸软、头晕耳鸣诸症治疗后较治疗前比,虽有改善,但差异无统计学意义(P0.05)。2服用养心通脉膏4周后,44例胸痹心痛(稳定型心绞痛)患者的SAQ量表评分显著高于治疗前,躯体活动受限程度、心绞痛稳定状态、心绞痛发作情况、治疗满意程度、疾病认知程度等各个维度的积分用药后较用药前比均有增加,且P0.05或0.01,差异具有统计学意义。结论:依托中医“治未病”的基础理论,以“衡”为期,自拟具有“益气和血、调补阴阳”之功效的养心通脉膏,可以改善胸痹心痛(稳定型心绞痛)患者的中医症状,提高胸痹心痛(稳定型心绞痛)患者的生活质量,从而改善胸痹心痛(稳定型心绞痛)患者的预后。
[Abstract]:Objective: to explore the clinical curative effect of Yangxin Tongmai ointment on chest arthralgia (stable angina pectoris) treated by "benefiting Qi and Blood, regulating Yin and Yang", and analyzing the mechanism of its clinical application. Methods: from January 2015 to January 2016, 44 patients with chest arthralgia (stable angina pectoris) were prospectively observed in the outpatient department of the second affiliated Hospital of Liaoning University of traditional Chinese Medicine. The epidemiological data, changes of TCM symptom score before and after medication, Seattle angina scale and so on were statistically analyzed to evaluate Yangxin Tongmai paste to "benefit qi and blood," The clinical effect of tonifying yin and yang on chest arthralgia (stable angina pectoris) and the pathogenesis of chest arthralgia (stable angina pectoris) were discussed. SPSS19.0 software was used for statistics, X2 test was used for counting data, T test was used for measuring data, and rank sum test was used for grade data. Results: 1After taking Yangxin Tongmai ointment for 4 weeks, the TCM symptoms of 44 patients with chest arthralgia (stable angina pectoris) were improved, including chest tightness, pain, palpitation short breath, burnout and fatigue, fear of cold limbs, self-sweating and annoyance. Insomnia and dreams and other symptoms were significantly improved, the difference was statistically significant (P0.05); But the waist and knee soft, dizziness and earsong symptoms after treatment than before treatment, although improved, but there was no significant difference (P0.05) .2After 4 weeks of Yangxin Tongmai ointment, there was no significant difference (P0.05). The scores of SAQ scale in 44 patients with chest arthralgia (stable angina pectoris) were significantly higher than those before treatment, the degree of physical activity restriction, the stable state of angina pectoris, the attack of angina pectoris, and the satisfactory degree of treatment. The scores of each dimension, such as cognitive degree of disease, were significantly higher than those before treatment, and the difference was statistically significant (P0.05 or 0.01). Conclusion: relying on the basic theory of "treating no disease" in traditional Chinese medicine and taking "Heng" for a period of time, the Yangxin Tongmai paste, which has the effect of "invigorating qi and blood, regulating yin and yang", can improve the TCM symptoms of patients with chest arthralgia (stable angina pectoris). To improve the quality of life of patients with chest arthralgia (stable angina pectoris) so as to improve the prognosis of patients with chest arthralgia (stable angina pectoris).
【学位授予单位】：辽宁中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R256.22
，
本文编号：2464555
[Abstract]:Objective: to explore the clinical curative effect of Yangxin Tongmai ointment on chest arthralgia (stable angina pectoris) treated by "benefiting Qi and Blood, regulating Yin and Yang", and analyzing the mechanism of its clinical application. Methods: from January 2015 to January 2016, 44 patients with chest arthralgia (stable angina pectoris) were prospectively observed in the outpatient department of the second affiliated Hospital of Liaoning University of traditional Chinese Medicine. The epidemiological data, changes of TCM symptom score before and after medication, Seattle angina scale and so on were statistically analyzed to evaluate Yangxin Tongmai paste to "benefit qi and blood," The clinical effect of tonifying yin and yang on chest arthralgia (stable angina pectoris) and the pathogenesis of chest arthralgia (stable angina pectoris) were discussed. SPSS19.0 software was used for statistics, X2 test was used for counting data, T test was used for measuring data, and rank sum test was used for grade data. Results: 1After taking Yangxin Tongmai ointment for 4 weeks, the TCM symptoms of 44 patients with chest arthralgia (stable angina pectoris) were improved, including chest tightness, pain, palpitation short breath, burnout and fatigue, fear of cold limbs, self-sweating and annoyance. Insomnia and dreams and other symptoms were significantly improved, the difference was statistically significant (P0.05); But the waist and knee soft, dizziness and earsong symptoms after treatment than before treatment, although improved, but there was no significant difference (P0.05) .2After 4 weeks of Yangxin Tongmai ointment, there was no significant difference (P0.05). The scores of SAQ scale in 44 patients with chest arthralgia (stable angina pectoris) were significantly higher than those before treatment, the degree of physical activity restriction, the stable state of angina pectoris, the attack of angina pectoris, and the satisfactory degree of treatment. The scores of each dimension, such as cognitive degree of disease, were significantly higher than those before treatment, and the difference was statistically significant (P0.05 or 0.01). Conclusion: relying on the basic theory of "treating no disease" in traditional Chinese medicine and taking "Heng" for a period of time, the Yangxin Tongmai paste, which has the effect of "invigorating qi and blood, regulating yin and yang", can improve the TCM symptoms of patients with chest arthralgia (stable angina pectoris). To improve the quality of life of patients with chest arthralgia (stable angina pectoris) so as to improve the prognosis of patients with chest arthralgia (stable angina pectoris).
【学位授予单位】：辽宁中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R256.22
，
本文编号：2464555
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