脑血疏口服液治疗气虚血瘀型急性脑梗死的临床研究

发布时间：2019-04-25 13:49

【摘要】：目的:探究脑血疏口服液治疗气虚血瘀型急性脑梗死的临床疗效,为临床广泛应用提供理论指导。方法:选取入住我院的78例气虚血瘀型急性脑梗死患者,对其进行随机对照分组。对照组38例患者应用常规西医治疗,治疗组40例患者在对照组治疗的基础上加用脑血疏口服液治疗,疗程14 d,观察对比两组患者的临床疗效、中医证候积分、NIHSS评分、ADL评分、凝血功能及不良反应发生率。结果:对照组患者的总有效率(81.57%)明显低于治疗组患者(92.50%,P0.05);两组患者治疗后的中医证候积分、NIHSS评分、ADL评分及凝血功能均较治疗前明显改善(P0.05),但治疗组患者的NIHSS评分、ADL评分及凝血功能显著优于对照组患者(P0.05);两组患者治疗期间均未出现严重的药物相关不良事件,无显著差异。结论:脑血疏口服液在治疗气虚血瘀型急性脑梗死方面具有较为显著的临床疗效,且毒副作用较小,值得临床推广应用。
[Abstract]:Objective: to explore the clinical efficacy of Naoxue Shu oral liquid in treating acute cerebral infarction of Qi deficiency and blood stasis type, and to provide theoretical guidance for clinical application. Methods: 78 patients with acute cerebral infarction of qi deficiency and blood stasis type were selected and randomly divided into control group. 38 patients in the control group were treated with routine western medicine, 40 patients in the treatment group were treated with Naoxue Shu oral liquid on the basis of the control group, the course of treatment was 14 days, the clinical curative effect, TCM syndrome integral and NIHSS score were observed and compared between the two groups. ADL score, coagulation function and incidence of adverse reactions. Results: the total effective rate of the control group (81.57%) was significantly lower than that of the treatment group (92.50%, P0.05). After treatment, the TCM syndrome score, NIHSS score, ADL score and coagulation function of the two groups were significantly improved (P0.05), but the NIHSS score, ADL score and coagulation function of the treatment group were significantly better than those of the control group (P0.05). No serious drug-related adverse events were found in the two groups during treatment, and there was no significant difference between the two groups. Conclusion: Naoxueshu oral liquid has obvious clinical curative effect in treating acute cerebral infarction of Qi deficiency and blood stasis type, and the toxicity and side effect are relatively small, so it is worthy of clinical popularization and application.
【作者单位】：河南中医药大学第一附属医院脑病一区;
【基金】：国家自然科学基金资助项目(81072799) 2015年河南省科技厅项目(152300410108)
【分类号】：R277.7

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