半夏秫米汤加减治疗湿热扰神型失眠的临床研究
发布时间：2019-04-29 18:22
【摘要】：目的:通过对半夏秫米汤加减治疗湿热扰神型失眠临床疗效指标的观察、统计分析,客观地评价半夏秫米汤加减治疗湿热扰神型失眠的临床疗效,对比中药与西药治疗失眠的优劣,为推广临床多用中医经方、验方加减治疗疾病奠定基础。材料与方法:本研究选取60例符合试验纳入标准的患者,运用随机数字表法平均分为治疗组和对照组,每组各30例。其中治疗组予以半夏秫米汤加减治疗,对照组予以佐匹克隆片治疗,7天为一个疗程,共3个疗程,并保证全程用药。统计治疗前后各患者匹兹堡睡眠质量指数(PSQI)积分和中医证候积分变化情况以及两组用药总有效率之间差异,并加以分析。结果:(1)治疗组和对照组治疗前后匹兹堡睡眠质量指数(PSQI)进行组内比较,统计分析结果:P0.05,有显著性差异;治疗组和对照组两组之间进行比较,统计分析结果:P0.05,无显著性差异,无统计学意义。(2)治疗组和对照组治疗前后中医证候积分进行组内比较,统计分析结果:P0.05,有显著性差异;治疗组和对照组两组之间进行比较,统计分析结果:P0.05,有显著性差异,具有统计学意义。(3)治疗组用药总有效率为86.7%,对照组用药总有效率为83.3%,治疗组与对照组总有效率大致相同,且统计分析结果:P0.05,无显著性差异,不具有统计学意义。结论:半夏秫米汤加减治疗湿热扰神型失眠有明确疗效,患者PSQI积分、中医证候积分均能够改善,且对于中医证候改善优于西药佐匹克隆,有一定的临床推广价值。以传统经方、验方进行加减化裁治疗疾病,能够在确保一定治疗效果的基础上更加优化治疗方案,更好的对患者进行治疗,提高临床疗效,降低临床风险。
[Abstract]:Objective: to evaluate objectively the clinical efficacy of Banxia sorghum rice decoction in the treatment of dampness-heat disturbance insomnia by observing and statistical analysis of the clinical curative effect of adding and decreasing Banxia sorghum rice decoction on damp-heat disturbing insomnia, and to evaluate objectively the clinical curative effect of Banxia sorghum rice decoction on damp-heat disturbance insomnia. To compare the advantages and disadvantages of traditional Chinese medicine (TCM) and western medicine in the treatment of insomnia, to lay a foundation for the promotion of clinical multi-use TCM prescriptions and the addition and subtractive treatment of diseases. Materials and methods: 60 patients were randomly divided into two groups: treatment group (n = 30) and control group (n = 30). The treatment group was treated with Banxia sorghum Millet decoction and the control group was treated with zopiclone tablets. The treatment group was treated with Zopiclone tablet for 7 days for a total of 3 courses, and the whole course of medication was guaranteed. The changes of Pittsburgh sleep quality index (PSQI) score and TCM syndrome score before and after treatment and the difference of total effective rate between the two groups were analyzed and analyzed. Results: (1) the Pittsburgh sleep quality index (PSQI) in the treatment group was compared with that in the control group before and after treatment. The statistical analysis showed that there was a significant difference between the treatment group and the control group (P 0.05). The results showed that there was no significant difference between the treatment group and the control group. (2) the TCM syndrome score of the treatment group was compared with that of the control group before and after treatment, and there was no significant difference between the treatment group and the control group. Statistical analysis results: P 0.05, there is a significant difference; (3) the total effective rate was 86.7% in the treatment group and 83.3% in the control group, and the total effective rate in the control group was 83.3%, and the total effective rate was 86.7% in the treatment group and 83.3% in the control group, the statistical analysis showed that there was significant difference between the treatment group and the control group. The total effective rate of the treatment group was the same as that of the control group, and the result of statistical analysis: P 0.05, there was no significant difference between the treatment group and the control group. Conclusion: Banxia sorghum rice decoction has definite curative effect in the treatment of dampness-heat disturbance insomnia. The PSQI score and TCM syndrome integral can be improved, and the improvement of TCM syndrome is better than that of Zopicone, which has a certain clinical value. The traditional prescription and the traditional prescription can optimize the treatment scheme, improve the clinical efficacy and reduce the clinical risk on the basis of ensuring a certain therapeutic effect on the basis of the treatment of the disease by the traditional prescription and the verification prescription.
【学位授予单位】：辽宁中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R256.23
，
本文编号：2468428
[Abstract]:Objective: to evaluate objectively the clinical efficacy of Banxia sorghum rice decoction in the treatment of dampness-heat disturbance insomnia by observing and statistical analysis of the clinical curative effect of adding and decreasing Banxia sorghum rice decoction on damp-heat disturbing insomnia, and to evaluate objectively the clinical curative effect of Banxia sorghum rice decoction on damp-heat disturbance insomnia. To compare the advantages and disadvantages of traditional Chinese medicine (TCM) and western medicine in the treatment of insomnia, to lay a foundation for the promotion of clinical multi-use TCM prescriptions and the addition and subtractive treatment of diseases. Materials and methods: 60 patients were randomly divided into two groups: treatment group (n = 30) and control group (n = 30). The treatment group was treated with Banxia sorghum Millet decoction and the control group was treated with zopiclone tablets. The treatment group was treated with Zopiclone tablet for 7 days for a total of 3 courses, and the whole course of medication was guaranteed. The changes of Pittsburgh sleep quality index (PSQI) score and TCM syndrome score before and after treatment and the difference of total effective rate between the two groups were analyzed and analyzed. Results: (1) the Pittsburgh sleep quality index (PSQI) in the treatment group was compared with that in the control group before and after treatment. The statistical analysis showed that there was a significant difference between the treatment group and the control group (P 0.05). The results showed that there was no significant difference between the treatment group and the control group. (2) the TCM syndrome score of the treatment group was compared with that of the control group before and after treatment, and there was no significant difference between the treatment group and the control group. Statistical analysis results: P 0.05, there is a significant difference; (3) the total effective rate was 86.7% in the treatment group and 83.3% in the control group, and the total effective rate in the control group was 83.3%, and the total effective rate was 86.7% in the treatment group and 83.3% in the control group, the statistical analysis showed that there was significant difference between the treatment group and the control group. The total effective rate of the treatment group was the same as that of the control group, and the result of statistical analysis: P 0.05, there was no significant difference between the treatment group and the control group. Conclusion: Banxia sorghum rice decoction has definite curative effect in the treatment of dampness-heat disturbance insomnia. The PSQI score and TCM syndrome integral can be improved, and the improvement of TCM syndrome is better than that of Zopicone, which has a certain clinical value. The traditional prescription and the traditional prescription can optimize the treatment scheme, improve the clinical efficacy and reduce the clinical risk on the basis of ensuring a certain therapeutic effect on the basis of the treatment of the disease by the traditional prescription and the verification prescription.
【学位授予单位】：辽宁中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R256.23
，
本文编号：2468428
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