血必净注射液治疗急性胰腺炎临床观察

发布时间：2019-05-11 06:10

【摘要】：目的:本文通过血必净注射液治疗瘀热互结型急性胰腺炎的临床实验,探讨血必净注射液对瘀热互结型急性胰腺炎的作用机制及临床应用价值。资料与方法:使用前瞻性设计方法,随机选取2013年1月至2015年12月辽宁中医药大学附属医院普外科60例住院患者,随机分成血必净治疗组及常规治疗组两组,每组30例。两组均给予禁食水,胃肠减压,补液,预防感染,营养支持,胰酶抑制剂等常规西医治疗。血必净治疗组在常规西医治疗的基础上追加血必净注射液50ml+0.9%氯化钠注射液100ml,2次/日静滴。观察入院时、治疗3天及7天后疼痛程度,疼痛程度以疼痛数字评分计量表(NRS)计分来表示,腹痛消失时间,入院时、3天及7天后血尿淀粉酶水平及平均住院天数。7天1疗程。结果:血必净治疗组患者腹部疼痛缓解程度,血尿淀粉酶水平恢复正常时间,腹痛消失时间,平均住院天数与常规治疗组患者比较,P0.05,差异具有统计学意义。故血必净组疼痛程度缓解、血尿淀粉酶恢复时间、症状消失时间及平均住院天数均优于常规治疗组。结论:1.血必净注射液能够有效缓解患者治疗过程中腹痛程度,缩短血、尿淀粉酶恢复时间及住院时间。2.常规西医疗法与血必净注射液联合应用,具有良好的协同作用。3.血必净注射液联合常规西医疗法治疗急性胰腺炎疗效满意,整个治疗过程中无严重不良反应及副作用发生,此法值得在临床上推广应用。
[Abstract]:Objective: to explore the mechanism and clinical application value of Xuebijing injection in the treatment of acute pancreatitis caused by heat stasis and heat stasis through the clinical experiment of Xuebijing injection in the treatment of acute pancreatitis with heat stasis and heat stasis. Materials and methods: from January 2013 to December 2015, 60 inpatients in the Department of General surgery, affiliated Hospital of Liaoning University of traditional Chinese Medicine were randomly divided into two groups: Xuebijing treatment group (n = 30) and routine treatment group (n = 30). Both groups were treated with fasting water, gastrointestinal decompression, fluid replacement, infection prevention, nutritional support, trypsin inhibitor and other routine western medicine treatment. Xuebijing treatment group was supplemented with Xuebijing injection 50ml 0.9% sodium chloride injection 100ml twice a day on the basis of routine western medicine. The degree of pain was observed on admission, 3 days after treatment and 7 days after treatment. The degree of pain was expressed by the pain score scale (NRS). The time of disappearance of abdominal pain and the time of admission. Serum and urine amylase levels and average hospitalization days after 3 and 7 days. 7 days a course of treatment. Results: the degree of abdominal pain relief, the recovery time of serum and urine amylase level, the disappearance time of abdominal pain and the average hospitalization days in Xuebijing treatment group were significantly different from those in routine treatment group (P0.05). Therefore, the pain degree, blood and urine amylase recovery time, symptom disappearance time and average hospitalization days in Xuebijing group were better than those in routine treatment group. Conclusion: 1. Xuebijing injection can effectively alleviate the degree of abdominal pain and shorten the recovery time and hospitalization time of blood and urine amylase. 2. The combination of conventional western medicine therapy and Xuebijing injection has a good synergistic effect. 3. Xuebijing injection combined with conventional western medicine is effective in the treatment of acute pancreatitis, and there are no serious adverse reactions and side effects in the whole treatment process. This method is worth popularizing and applying in clinic.
【学位授予单位】：辽宁中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R259

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