防己黄芪汤合真武汤加减治疗气虚血瘀型慢性心力衰竭患者临床观察

发布时间：2019-05-13 08:40

【摘要】：目的:观察防己黄芪汤合真武汤加减治疗慢性心力衰竭气虚血瘀型患者的临床疗效。方法:将符合纳入标准的80例慢性心力衰竭(气虚血瘀型)患者,随机分为对照组与治疗组,各40例。对照组给予常规抗心衰西药治疗,包括血管紧张素转化酶抑制剂(angiotensin converting enzyme inhibitors,ACEI)或血管紧张素Ⅱ受体阻滞剂(angiotensinⅡreceptor blockers,ARB),扩血管药物,β受体阻滞剂,利尿剂,地高辛等;治疗组在常规治疗基础上加用防己黄芪汤合真武汤加减,共4周。观察两组患者治疗前与治疗后中医证候疗效、心功能分级比较、左室舒张末内径(left ventricular end diastole,LVED),左室收缩末内径(left ventricular end of systolic diameter,LVSD),左室射血分数(left ventricular ejection fraction,LVEF)。结果:经过治疗,在中医证候疗效方面,治疗组总有效率82.5%,优于对照组的65%(P0.05);在心功能分级比较方面,治疗组总有效率85%,优于对照组的60%(P0.05);在心功能指标方面,对照组和治疗组LVED和LVSD均降低,LVEF上升(P0.05);治疗组LVED和LVSD均低于对照组,LVEF高于对照组(P0.01)。结论:防己黄芪汤合真武汤加减在改善慢性心力衰竭患者的中医证候、心功能分级、以及改善心功能和心室重构方面具有一定作用。
[Abstract]:Objective: to observe the clinical effect of Fangji Huangqi decoction combined with Zhenwu decoction in the treatment of chronic heart failure with qi deficiency and blood stasis. Methods: 80 patients with chronic heart failure (Qi deficiency and blood stasis type) were randomly divided into control group (n = 40) and treatment group (n = 40). The control group was treated with conventional western medicine against heart failure, including angiotensin converting enzyme inhibitor (angiotensin converting enzyme inhibitors,ACEI or angiotensin II receptor blockers,ARB, vasodilator, 尾 receptor blocker and diuretic. Digoxin, et al. On the basis of routine treatment, the treatment group was treated with Fangji Huangqi decoction and Zhenwu decoction for 4 weeks. The curative effect of TCM syndromes, cardiac function grade, left ventricular end-diastolic diameter (left ventricular end diastole,LVED), left ventricular end-systolic diameter (left ventricular end of systolic diameter,LVSD) and left ventricular ejection fraction (left ventricular ejection fraction,LVEF) were observed before and after treatment. Results: after treatment, the total effective rate of the treatment group was 82.5%, which was better than that of the control group (P 0.05). In the comparison of cardiac function classification, the total effective rate of the treatment group was 85%, which was better than that of the control group (60%). In the heart function index, the LVED and LVSD of the control group and the treatment group were decreased, and the LVEF was increased (P 0.05). LVED and LVSD in the treatment group were lower than those in the control group, and LVEF was higher than that in the control group (P 0.01). Conclusion: Fangji Huangqi decoction and Zhenwu decoction can improve TCM syndrome, cardiac function grade, cardiac function and ventricular remodeling in patients with chronic heart failure.
【作者单位】：牡丹江医学院附属红旗医院;黑龙江中医药大学;
【基金】：黑龙江省卫生厅科研项目(2012-298)
【分类号】：R259

【相似文献】