膝骨性关节炎中医证素与WOMAC特征及影像学相关性探讨

发布时间：2019-05-19 17:34

【摘要】：目的:探索骨性关节炎中医证素分布及与WOMAC特征及影像学相关性。方法:2015年1月—2016年12月,纳入医院骨伤科门诊及住院的膝骨性关节炎患者200例。对患者一般资料、中医症候要素、中医证素、WOMAC疼痛问卷、X线、MRI资料进行统计。采用频数分析、logistic回归分析。结果:膝骨性关节炎高频次证素为肾190例,肝178例,脾、胃均为80例;风192例、瘀188例、湿172例、寒139例、阳虚125例;WOMAC疼痛问卷积分与中医证素相关分析中,肝、肾、寒、瘀差异有统计学意义(P0.05);X线Kelgren和Lawrence法分级与中医证素相关分析中,肾、瘀差异有统计学意义(P0.05);MRI软骨损伤Recht标准分级与中医证素相关分析中,肾、瘀差异有统计学意义(P0.05)。结论:中医证素与临床症状及影像学可综合评价研究膝骨性关节炎,可以为更全面进行膝骨性关节炎疾病的中医诊疗提供参考。
[Abstract]:Objective: to explore the distribution of TCM syndrome elements in osteoarthritis and its correlation with WOMAC features and imaging features. Methods: from January 2015 to December 2016, 200 patients with knee osteoarthritis were enrolled in orthopedic department. The general data of patients, TCM syndrome elements, WOMAC pain questionnaire, X-ray and MRI data were statistically analyzed. Frequency analysis and logistic regression analysis were used. Results: there were 190 cases of kidney, 178 cases of liver, 80 cases of spleen and stomach, 192 cases of wind, 188 cases of blood stasis, 172 cases of dampness, 139 cases of cold and 125 cases of yang deficiency. There was significant difference in liver, kidney, cold and blood stasis between WOMAC pain questionnaire score and TCM syndrome element correlation analysis (P 0.05), and there was significant difference in kidney and blood stasis between X-ray Kelgren and Laurence classification and TCM syndrome element correlation analysis (P 0.05), and there was significant difference in liver, kidney, cold and blood stasis between TCM pain questionnaire score and TCM syndrome element correlation analysis (P 0.05). In the correlation analysis between Recht standard grade of MRI cartilage injury and TCM syndrome elements, there was significant difference in kidney and blood stasis (P 0.05). Conclusion: TCM syndrome element, clinical symptoms and imaging can be comprehensively evaluated and studied in knee osteoarthritis, which can provide reference for more comprehensive diagnosis and treatment of knee osteoarthritis.
【作者单位】：浙江中医药大学附属温州中医院骨科;浙江中医药大学附属温州中医院药剂科;福建中医药大学中西医结合研究院;
【基金】：浙江省中医药科技计划项目(2015ZQ031)
【分类号】：R274.9

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