四妙丸合宣痹汤加减治疗痛风80例临床观察

发布时间：2019-05-28 11:38

【摘要】：目的:探讨中医辨证施治痛风的疗效。方法:80名患者分成随机两组,分别采用四妙丸合宣痹汤加减治疗(观察组)和西药常规治疗(对照组)。结果:观察组总疗效优于对照组(P0.05);两组患者血尿酸、关节疼痛度、关节肿胀度等指标治疗前后比较均有明显改善(P0.05),观察组降低血尿酸水平与对照组比较有显著性差异(P0.05);观察组无明显毒副反应发生,而对照组出现了骨髓抑制、肾功能损害、肝功能损害、消化道反应等毒副反应,即观察组药物安全性与对照组比较有显著性差异(P0.05);且观察组停药复发率远低于对照组,两组远期疗效差异具有统计学意义(P0.05)。结论:四妙丸合宣痹汤加减治疗痛风(湿热蕴结型)疗效优于西药常规治疗。
[Abstract]:Objective: to explore the curative effect of TCM syndrome differentiation in the treatment of gout. Methods: eighty patients were randomly divided into two groups and treated with Simiao pills and Xuanbi decoction (observation group) and routine western medicine treatment (control group). Results: the total curative effect of the observation group was better than that of the control group (P 0.05). The indexes of serum uric acid, joint pain and joint swelling in the two groups were significantly improved before and after treatment (P 0.05), and there was significant difference in the decrease of serum uric acid level between the observation group and the control group (P 0.05). There were no obvious side effects in the observation group, but there were some side effects in the control group, such as bone marrow suppression, renal function damage, liver function damage, digestive tract reaction and so on, that is, the drug safety of the observation group was significantly different from that of the control group (P 0.05). The recurrence rate of drug withdrawal in the observation group was much lower than that in the control group, and there was significant difference in the long-term curative effect between the two groups (P 0.05). Conclusion: Simiao pills combined with Xuanbi decoction is superior to routine western medicine in the treatment of gout (dampness-heat accumulation type).
【作者单位】：新建区人民医院中医科;解放军第94医院内一科;
【分类号】：R259

【相似文献】