李铁教授养阴解毒法治疗特发性血小板减少性紫癜的经验
发布时间：2019-05-30 01:27
【摘要】：特发性血小板减少性紫癜(idiopathic thrombocytopenic purpura,ITP)是一组免疫介导的血小板破坏过多而导致的出血性疾病,其临床表现主要有广泛的皮肤黏膜和内脏出血、血小板减少、骨髓巨核细胞发育成熟障碍、出血时间延长、及血小板膜糖蛋白特异性自身抗体出现等。在中医上可将本病归属“血证”、“发斑”、“肌衄”等范畴。李铁教授认为“热”、“瘀”、“湿”、“虚”是本病发生及进展过程中的主要病机变化,运用养阴解毒法治疗阴虚型的血小板减少性紫癜,并提出了“兼顾清热凉血,配伍活血散血,不离醒脾化湿”的养阴解毒原则。以四草四根汤为基础方,配伍养阴、清热、解毒、祛瘀、化湿等中药。选取门诊27例符合诊断标准的ITP患者,观察李铁教授养阴解毒法治疗ITP的临床疗效。
[Abstract]:Idiopathic Thrombocytopenic Purpura (idiopathic thrombocytopenic purpura,ITP) is a group of hemorrhagic diseases caused by immune-mediated platelet destruction. Its clinical manifestations are extensive skin, mucous membrane and visceral bleeding, and thrombopenia. Bone marrow megakaryocytes developed and matured, bleeding time prolonged, and platelet membrane glycoprotein specific autoantibodies appeared. In traditional Chinese medicine, the disease can be classified into "blood syndrome", "plaque", "muscle bleeding" and other categories. Professor Li Tie believes that "heat", "blood stasis", "dampness" and "deficiency" are the main pathogenesis changes in the occurrence and progress of the disease. The method of nourishing yin and detoxification is used to treat thrombocytopenic purpura of yin deficiency type, and he put forward that "clearing away heat and cooling blood" The principle of nourishing yin and detoxification is compatible with promoting blood circulation and dispersing blood, not leaving the spleen to dissipate dampness. Based on Sicao Sigan decoction, it is compatible with traditional Chinese medicine such as nourishing yin, clearing away heat, detoxifying, removing blood stasis, removing dampness and so on. 27 patients with ITP who met the diagnostic criteria were selected to observe the clinical effect of Professor Li Tie's method of nourishing yin and detoxifying in the treatment of ITP.
【学位授予单位】：辽宁中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R249;R259
，
本文编号：2488389
[Abstract]:Idiopathic Thrombocytopenic Purpura (idiopathic thrombocytopenic purpura,ITP) is a group of hemorrhagic diseases caused by immune-mediated platelet destruction. Its clinical manifestations are extensive skin, mucous membrane and visceral bleeding, and thrombopenia. Bone marrow megakaryocytes developed and matured, bleeding time prolonged, and platelet membrane glycoprotein specific autoantibodies appeared. In traditional Chinese medicine, the disease can be classified into "blood syndrome", "plaque", "muscle bleeding" and other categories. Professor Li Tie believes that "heat", "blood stasis", "dampness" and "deficiency" are the main pathogenesis changes in the occurrence and progress of the disease. The method of nourishing yin and detoxification is used to treat thrombocytopenic purpura of yin deficiency type, and he put forward that "clearing away heat and cooling blood" The principle of nourishing yin and detoxification is compatible with promoting blood circulation and dispersing blood, not leaving the spleen to dissipate dampness. Based on Sicao Sigan decoction, it is compatible with traditional Chinese medicine such as nourishing yin, clearing away heat, detoxifying, removing blood stasis, removing dampness and so on. 27 patients with ITP who met the diagnostic criteria were selected to observe the clinical effect of Professor Li Tie's method of nourishing yin and detoxifying in the treatment of ITP.
【学位授予单位】：辽宁中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R249;R259
，
本文编号：2488389
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