壮医药线点灸疗法治疗寻常型银屑病的临床观察

发布时间：2019-06-05 08:30

【摘要】：目的:观察壮医药线点灸结合西医常规疗法治疗寻常型银屑病的临床疗效及安全性,为临床上使用该疗法治疗寻常型银屑病提供依据。方法:首先采用随机数字表法,将50例寻常型银屑病患者随机分为试验组25例,对照组25例。对照组采用西医常规疗法治疗,疗程30天。试验组在对照组的治疗基础上加用壮医药线点灸疗法治疗,壮医药线点灸疗法隔天治疗1次,共治疗15次。疗程结束后,对皮损面积和严重程度(PASI)进行疗效评价,对瘙痒等级、皮肤病生活质量指数量表(DLQI)、汉密顿焦虑量表(HAMA)(包括焦虑心境、紧张、失眠等)进行评价分析。采用实验室安全性评价指标及不良事件发生情况对结局进行安全性评价。结果:经30天治疗后,两组各有25例完成试验。试验组达到临床治愈的0例、显效13例、有效9例、无效3例,有效率88%;对照组达到临床治愈的0例、显效4例、有效10例、无效11例,有效率56%。两组有效率比较,差异有统计学意义(P0.05)。在改善患者皮损面积和严重程度、减轻瘙痒、缓解焦虑、提高患者生活质量方面,试验组优于对照组,两组差异有显著统计学意义(P0.01);两组均未出现安全性指标异常。对照组1例患者出现轻微恶心、腹泻;试验组1例患者点灸一段时间后点灸局部出现浅表的灼伤痕迹伴瘙痒,症状轻微。结论:壮医药线点灸结合西医常规疗法治疗寻常型银屑病在改善患者皮损面积和严重程度、减轻瘙痒、缓解焦虑、提高患者生活质量等方面的临床疗效,优于单独使用西医常规疗法,且无明显不良反应及毒副作用,安全性高。
[Abstract]:Objective: to observe the clinical efficacy and safety of Zhuang medicine line moxibustion combined with routine western medicine therapy in the treatment of psoriasis vulgaris, and to provide evidence for clinical use of this therapy in the treatment of psoriasis vulgaris. Methods: 50 patients with psoriasis vulgaris were randomly divided into experimental group (n = 25) and control group (n = 25). The control group was treated with routine western medicine for 30 days. On the basis of the treatment of the control group, the experimental group was treated with Zhuang medicine line moxibustion therapy, and Zhuang medicine line moxibustion therapy was treated once every other day for a total of 15 times. At the end of the course of treatment, the curative effect of (PASI) on skin lesion area and severity was evaluated. For pruritus grade, skin disease quality of life index scale (DLQI), Hamilton anxiety scale (HAMA) (, including anxiety mood, tension. Insomnia, etc.) for evaluation and analysis. The safety evaluation index of laboratory and the occurrence of adverse events were used to evaluate the safety of the outcome. Results: after 30 days of treatment, 25 cases in each group completed the trial. In the experimental group, 0 cases were clinically cured, 13 cases were markedly effective, 9 cases were effective, 3 cases were ineffective, the effective rate was 88%, while in the control group, 0 cases were clinically cured, 4 cases were markedly effective, 10 cases were effective, 11 cases were ineffective, the effective rate was 56%. There was significant difference in the effective rate between the two groups (P 0.05). The experimental group was superior to the control group in improving the area and severity of skin lesions, reducing pruritus, relieving anxiety and improving the quality of life of the patients, and there was significant difference between the two groups (P 0.01). There was no abnormal safety index between the two groups. One patient in the control group had slight nausea and diarrhea, and one patient in the experimental group had superficial burn marks with pruritus after moxibustion for a period of time, and the symptoms were mild. Conclusion: Zhuang medicine line moxibustion combined with routine western medicine therapy in the treatment of psoriasis vulgaris is effective in improving the area and severity of skin lesions, reducing pruritus, relieving anxiety and improving the quality of life of patients. It is superior to routine western medicine alone, and has no obvious adverse reactions and side effects, and has high safety.
【学位授予单位】：广西中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R29

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