丁元庆教授治疗不寐阴虚血瘀证临床总结及规律探讨
发布时间：2019-06-14 08:15
【摘要】：目的:基于中医传承辅助平台,分析名中医丁元庆教授治疗不寐阴虚血瘀证的临床特点和用药经验,从而丰富和优化基于名医经验的不寐阴虚血瘀证的诊疗方案,为不寐阴虚血瘀证的中医药诊疗思路提供参考。方法:采用关联规则apriori算法、复杂系统熵聚类等无监督数据挖掘方法,分析丁元庆教授治疗不寐阴虚血瘀证的病案及处方,确定处方中各种药物的使用频次及药物之间的关联规则,探析丁元庆教授治疗不寐阴虚血瘀证的用药规律。结果:通过对708例病案进行分析,显示不寐阴虚血瘀证的关键辨证症状为绝经、口干、口苦、大便干、大便不畅、多汗、大便溏泄、坚硬肿块、耳聋耳鸣、体重减轻、暗红舌、红绛舌、齿痕舌、裂纹舌、瘀斑舌、黄苔、薄苔、燥苔、少苔、弦脉、细脉等。对708首处方进行分析,得到丁元庆教授治疗不寐阴虚血瘀证的常用药物为麦冬、酸枣仁、丹参、百合、天麻、珍珠母、竹叶、牛膝、北沙参、玉竹、夏枯草、郁金、天冬、川贝母、当归、茯苓,并通过复杂熵聚类方法挖掘出20个潜在药物组合和10组候选新药队。结论:丁元庆教授治疗不寐阴虚血瘀证强调养阴在先,化瘀凉血继之,兼顾清心、宁心、安神。养阴首重养心阴,安心神,滋补心阴与清心安神兼顾。治疗心阴虚用药主以甘寒。
[Abstract]:Objective: to analyze the clinical characteristics and drug use experience of Professor Ding Yuanqing in the treatment of insomnia yin deficiency and blood stasis syndrome based on the inheritance auxiliary platform of traditional Chinese medicine, so as to enrich and optimize the diagnosis and treatment scheme of insomnia yin deficiency and blood stasis syndrome based on the experience of famous doctors, and to provide reference for the diagnosis and treatment of insomnia yin deficiency and blood stasis syndrome. Methods: unsupervised data mining methods such as association rule apriori algorithm and complex system entropy clustering were used to analyze the medical records and prescriptions of Professor Ding Yuanqing in the treatment of insomnia yin deficiency and blood stasis syndrome, to determine the frequency of use of various drugs in the prescription and the association rules among drugs, and to explore the drug use law of Professor Ding Yuanqing in the treatment of insomnia yin deficiency and blood stasis syndrome. Results: through the analysis of 708 cases, the key syndrome differentiation symptoms of insomnia yin deficiency and blood stasis syndrome were menopausal, dry mouth, bitter mouth, dry stool, unsmooth stool, loose stool, hard mass, deafness tinnitus, weight loss, dark red tongue, red crimson tongue, tooth mark tongue, split tongue, ecchymosis tongue, yellow moss, thin moss, dry moss, less moss, string vein, veinlets and so on. According to the analysis of 708 prescriptions, the common drugs used by Professor Ding Yuanqing in the treatment of insomnia yin deficiency and blood stasis syndrome were as follows: Ophiopogon, jujube kernel, salvia miltiorrhiza, lily, Gastrodia elata, pearl mother, bamboo leaves, Achyranthes bidentata, Phyllostachys pubescens, Yujin, Tiandong, Fritillaria thunbergii, Angelica sinensis and Poria umbellus, and 20 potential drug combinations and 10 groups of candidate new drug teams were excavated by complex entropy clustering method. Conclusion: professor Ding Yuanqing in the treatment of insomnia yin deficiency and blood stasis syndrome emphasizes that nourishing yin first, removing blood stasis and cooling blood, giving consideration to clearing the heart, calming the heart and calming the mind. Nourish yin first nourish heart yin, reassure god, nourish heart yin and clear heart tranquilize mind. The main medicine for treating deficiency of heart yin is sweet cold.
【学位授予单位】：山东中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R249;R256.23
[Abstract]:Objective: to analyze the clinical characteristics and drug use experience of Professor Ding Yuanqing in the treatment of insomnia yin deficiency and blood stasis syndrome based on the inheritance auxiliary platform of traditional Chinese medicine, so as to enrich and optimize the diagnosis and treatment scheme of insomnia yin deficiency and blood stasis syndrome based on the experience of famous doctors, and to provide reference for the diagnosis and treatment of insomnia yin deficiency and blood stasis syndrome. Methods: unsupervised data mining methods such as association rule apriori algorithm and complex system entropy clustering were used to analyze the medical records and prescriptions of Professor Ding Yuanqing in the treatment of insomnia yin deficiency and blood stasis syndrome, to determine the frequency of use of various drugs in the prescription and the association rules among drugs, and to explore the drug use law of Professor Ding Yuanqing in the treatment of insomnia yin deficiency and blood stasis syndrome. Results: through the analysis of 708 cases, the key syndrome differentiation symptoms of insomnia yin deficiency and blood stasis syndrome were menopausal, dry mouth, bitter mouth, dry stool, unsmooth stool, loose stool, hard mass, deafness tinnitus, weight loss, dark red tongue, red crimson tongue, tooth mark tongue, split tongue, ecchymosis tongue, yellow moss, thin moss, dry moss, less moss, string vein, veinlets and so on. According to the analysis of 708 prescriptions, the common drugs used by Professor Ding Yuanqing in the treatment of insomnia yin deficiency and blood stasis syndrome were as follows: Ophiopogon, jujube kernel, salvia miltiorrhiza, lily, Gastrodia elata, pearl mother, bamboo leaves, Achyranthes bidentata, Phyllostachys pubescens, Yujin, Tiandong, Fritillaria thunbergii, Angelica sinensis and Poria umbellus, and 20 potential drug combinations and 10 groups of candidate new drug teams were excavated by complex entropy clustering method. Conclusion: professor Ding Yuanqing in the treatment of insomnia yin deficiency and blood stasis syndrome emphasizes that nourishing yin first, removing blood stasis and cooling blood, giving consideration to clearing the heart, calming the heart and calming the mind. Nourish yin first nourish heart yin, reassure god, nourish heart yin and clear heart tranquilize mind. The main medicine for treating deficiency of heart yin is sweet cold.
【学位授予单位】：山东中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R249;R256.23
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