辨证针刺治疗脾胃气虚型餐后不适综合征的临床疗效观察及人口学特点分析
发布时间：2019-06-21 14:23
【摘要】：目的：评价辨证针刺治疗脾胃气虚型餐后不适综合征(Postprandial Distress Syndrome, PDS)的临床疗效,在研究人口学特征与疾病的相关性的基础上,探讨人口学特征对针刺效应的影响,为辨证针刺治疗PDS的临床运用提供研究依据。方法：1、采用随机对照的研究方法,将97例PDS患者随机分为A组(辨证针刺组)、B组(非经非穴组),根据不同取穴方案,每组受试者每日接受1次时长30分钟的电针治疗,共20次,以尼平消化不良指数(Nepean Dyspepsia Index, NDI)的症状积分表和生活质量评分表为评价指标,分别于入组时、治疗结束、结束后4周随访时评价两组治疗对PDS患者症状和生活质量(Quality of life, QoL)的影响。2、在搜集97例脾胃气虚型PDS受试者的基线资料,通过对基线数据的统计分析,分析其人口学特点的基础上,采用相关性分析,探讨PDS患者人口学特征对针刺效应的影响。结果：1、辨证针刺治疗PDS的临床疗效评价(1)针刺治疗对PDS患者症状的影响：组内比较的结果显示：与针刺前相比,辨证针刺组在治疗后与随访时都呈现了统计学差异(P=0.000)：非经非穴组在治疗后与随访时也都呈现了统计学差异(P=0.000)。组间比较的结果显示：与非经非穴组相比,辨证针刺在入组第4周至第8周之间,均可以显著降低患者上腹部不适、餐后胀满或消化缓慢、腹部胀气、恶心的症状评分,差异具有统计学意义(P0.05)；(2)针刺治疗对PDS患者生活质量的影响：组内比较的结果显示：与针刺前相比,辨证针刺组在治疗后与随访时都呈现了统计学差异(P=0.000)；非经非穴组在治疗后与随访时也都呈现了统计学差异(P=0.000)。组间比较的结果显示：与非经非穴组相比,辨证针刺在入组第4周至第8周之间可以显著改善NDI生活质量评分量表干扰领域、认识和控制领域、食物饮料领域、睡眠领域四个领域的评分,差异具有统计学意义(P0.05)。2、人口学特征对针刺治疗PDS疗效影响研究(1)PDS患者的人口学特点及其与疾病的相关性在所有受试者中,性别上：女性患者占比重较大；年龄上：青年患者占比重较大；职业和教育上：高学历患者、职员和学生占比例较大,均具有统计学差异(P0.05)；年龄与上腹部不适、不按规律进餐和睡眠领域的评分具有显著相关性,有统计学意义(P0.05)。(2)年龄对针刺治疗PDS疗效的影响治疗后,以老年人为对照,青年人和中年人的P值分别为0.011和0.032；在第8周时,青年人和中年人的P值为0.015和0.229,两组均具有统计学差异(P0.05)。结论：1、辨证针刺治疗脾胃气虚型PDS疗效优于非经非穴,辨证针刺和非经非穴均能明显改善受试者的症状和生活质量。2、年龄和性别是PDS发病的重要影响因素,年轻人和女性更容易患PDS,其原因与教育、职业以及性别生理差异有关,并且年龄与上腹部不适、不能按规律进餐的症状评分呈正相关关系。3、年龄是影响针刺治疗PDS疗效的因素。
[Abstract]:Objective: to evaluate the clinical effect of syndrome differentiation acupuncture on postmeal discomfort syndrome (Postprandial Distress Syndrome, PDS) with spleen and stomach qi deficiency type, and to explore the influence of demographic characteristics on acupuncture effect on the basis of studying the correlation between demographic characteristics and diseases, so as to provide research basis for clinical application of syndrome differentiation acupuncture in the treatment of PDS. Methods: 1. 97 patients with PDS were randomly divided into group A (syndrome differentiation acupuncture group), B group). According to different acupoint selection schemes, each group received 30 minutes of electro-acupuncture treatment once a day for 20 times. The symptom score table and quality of life score table of niping dyspepsia index (Nepean Dyspepsia Index, NDI) were used as evaluation indexes, and the treatment ended at the time of admission. The effects of treatment on symptoms and quality of life (Quality of life, QoL) of PDS patients were evaluated at 4 weeks after follow-up. 2. Based on the collection of baseline data of 97 PDS subjects with spleen and stomach qi deficiency type, the demographic characteristics of PDS patients were analyzed by statistical analysis, and the effect of demographic characteristics on acupuncture effect was discussed by correlation analysis. Results: 1. Evaluation of clinical efficacy of syndrome differentiation acupuncture in the treatment of PDS (1) the effect of acupuncture treatment on the symptoms of PDS patients: the results of intra-group comparison showed that compared with before acupuncture, there was significant difference after treatment and follow-up in syndrome differentiation acupuncture group (P 鈮，
本文编号：2504142
[Abstract]:Objective: to evaluate the clinical effect of syndrome differentiation acupuncture on postmeal discomfort syndrome (Postprandial Distress Syndrome, PDS) with spleen and stomach qi deficiency type, and to explore the influence of demographic characteristics on acupuncture effect on the basis of studying the correlation between demographic characteristics and diseases, so as to provide research basis for clinical application of syndrome differentiation acupuncture in the treatment of PDS. Methods: 1. 97 patients with PDS were randomly divided into group A (syndrome differentiation acupuncture group), B group). According to different acupoint selection schemes, each group received 30 minutes of electro-acupuncture treatment once a day for 20 times. The symptom score table and quality of life score table of niping dyspepsia index (Nepean Dyspepsia Index, NDI) were used as evaluation indexes, and the treatment ended at the time of admission. The effects of treatment on symptoms and quality of life (Quality of life, QoL) of PDS patients were evaluated at 4 weeks after follow-up. 2. Based on the collection of baseline data of 97 PDS subjects with spleen and stomach qi deficiency type, the demographic characteristics of PDS patients were analyzed by statistical analysis, and the effect of demographic characteristics on acupuncture effect was discussed by correlation analysis. Results: 1. Evaluation of clinical efficacy of syndrome differentiation acupuncture in the treatment of PDS (1) the effect of acupuncture treatment on the symptoms of PDS patients: the results of intra-group comparison showed that compared with before acupuncture, there was significant difference after treatment and follow-up in syndrome differentiation acupuncture group (P 鈮，
本文编号：2504142
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