中草药治疗哮喘的免疫调节作用最新研究进展
发布时间：2019-08-07 10:00
【摘要】：哮喘是由多种免疫细胞参与的慢性呼吸道炎症疾病,常常导致气促、胸闷、咳嗽以及反复发作的喘息等症状,往往出现气流阻塞,影响人体健康。中草药(CHM)用于治疗哮喘已经有上千年的历史,大量研究表明中草药能有效的调节细胞免疫反应减缓哮喘症状。该文综述了近几年来中草药对免疫细胞的调节作用及相关分子机制的研究,包括炎症细胞数量、树突状细胞成熟、辅助性T细胞亚型之间的平衡、调节性T细胞的诱导及胞内信号通路,并展望了未来的研究方向。
[Abstract]:Asthma is a chronic airway inflammation disease, which is involved in many immune cells, which often leads to the symptoms of shortness of breath, chest distress, cough, and wheezing and other symptoms, and the air flow is often blocked and the health of the human body is affected. Chinese herbal medicine (CHM) has been used in the treatment of asthma, and a large number of studies have shown that the Chinese herbal medicine can effectively regulate cellular immune response and slow the symptoms of asthma. The effects of Chinese herbal medicines on immune cells and related molecular mechanisms in recent years have been reviewed, including the number of inflammatory cells, the maturation of dendritic cells, the balance between the helper T-cell subtypes, the induction of regulatory T cells and the intracellular signaling pathway, And the future research direction is also looked forward.
【作者单位】： 新疆生物资源基因工程重点实验室新疆大学生命科学与技术学院;乌鲁木齐市第二十三中学;
【基金】：国家自然科学基金项目(31460241)
【分类号】：R256.12
[Abstract]:Asthma is a chronic airway inflammation disease, which is involved in many immune cells, which often leads to the symptoms of shortness of breath, chest distress, cough, and wheezing and other symptoms, and the air flow is often blocked and the health of the human body is affected. Chinese herbal medicine (CHM) has been used in the treatment of asthma, and a large number of studies have shown that the Chinese herbal medicine can effectively regulate cellular immune response and slow the symptoms of asthma. The effects of Chinese herbal medicines on immune cells and related molecular mechanisms in recent years have been reviewed, including the number of inflammatory cells, the maturation of dendritic cells, the balance between the helper T-cell subtypes, the induction of regulatory T cells and the intracellular signaling pathway, And the future research direction is also looked forward.
【作者单位】： 新疆生物资源基因工程重点实验室新疆大学生命科学与技术学院;乌鲁木齐市第二十三中学;
【基金】：国家自然科学基金项目(31460241)
【分类号】：R256.12
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