机械活化增强多孔磷酸钙骨水泥支架的研究

发布时间：2018-06-17 03:45

本文选题：磷酸钙骨水泥 + 球磨　；参考：《无机材料学报》2015年04期

【摘要】：本研究采用球磨对磷酸钙骨水泥(CPC)起始粉末进行机械活化处理,以期改善CPC力学性能,并探讨了其影响机理。采用激光粒度仪、比表面积测量仪和X射线衍射仪(XRD)表征球磨后的CPC粉末(Ball milling CPC,BCPC)。利用发泡法制备多孔BCPC支架,采用万能力学试验机、XRD和扫描电子显微镜(SEM)表征多孔BCPC支架。结果显示,球磨后的BCPC粉末平均粒径减小,比表面积增大,表观密度、堆积密度及紧密密度减小。BCPC支架孔隙率为(77.98?0.58)%,抗压强度为(4.11?0.46)MPa,相比CPC支架的(64.23?2.32)%和(1.99?0.43)MPa有显著提高。SEM结果显示BCPC支架具有数微米和数百微米的两种孔隙结构。XRD结果表明机械活化作用降低了DCPD、?-TCP、Ca CO3和HA的晶粒尺寸和结晶度,促使DCPD向DCPA转化,促进了各相磷酸钙盐的水化和HA的沉积,提高了BCPC支架的力学性能,为增强Ca P基多孔材料的力学性能和扩展其临床应用提供了新途径。
[Abstract]:In order to improve the mechanical properties of calcium phosphate cement (CPC), the mechanical activation of CPC powder by ball milling was studied in order to improve the mechanical properties of CPC, and the mechanism of its influence was discussed. Laser particle size measurement, specific surface area measurement and X-ray diffractometer (XRD) were used to characterize the milled CPC powder. Porous BCPC scaffolds were prepared by foaming method. The porous BCPC scaffolds were characterized by universal mechanical testing machine (XRD) and scanning electron microscope (SEM). The results showed that the average particle size, specific surface area and apparent density of BCPC powder decreased after ball milling. Bulk density and tight density decrease. Porosity of BCPC scaffold is 77.98 / 0.58 and compressive strength is 4.110.46 / MPa. Compared with CPC scaffold, the porosity of BCPC scaffold is significantly increased by 64.23 ~ 2.32% and 1.99 ~ 0.43 MPA. SEM results show that BCPC scaffold has two kinds of pore structures of several microns and hundreds of microns. XRD results show that BCPC scaffold has two kinds of pore structures: several microns and hundreds of microns. The results of XRD show that BCPC scaffolds have two kinds of pore structures. The mechanical activation decreased the grain size and crystallinity of DCPDX TCPC Caco 3 and HA. It promotes the transformation of DCPD to DCPA, promotes the hydration of calcium phosphate and the deposition of HA in all phases, improves the mechanical properties of BCPC scaffolds, and provides a new way to enhance the mechanical properties and expand the clinical application of CP-based porous materials.
【作者单位】：西南交通大学材料科学与工程学院材料先进技术教育部重点实验室;
【基金】：973项目(2012CB933602) 国家自然科学基金(51372210) 教育部博士点基金(20130184110023) 四川省高校科研创新团队建设计划项目(14TD0050)~~
【分类号】：TQ172.1

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